Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rodrick P. Taylor"'
Publikováno v:
Current Signal Transduction Therapy. 5:3-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edcd4470e46ba218052c797bf2be90dd
https://doi.org/10.2174/157436210790226474
https://doi.org/10.2174/157436210790226474
Publikováno v:
Journal of Biological Chemistry. 284:3425-3432
O-Linked N-acetylglucosamine (O-GlcNAc) is a post-translational modification of proteins that functions as a nutrient sensing mechanism. We have previously shown a significant induction of O-GlcNAc modification under conditions of glucose deprivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b497631a5d0bb230b1931af09a22555a
https://doi.org/10.1074/jbc.m803198200
https://doi.org/10.1074/jbc.m803198200
Autor:
Donald A. McClain, Rodrick P. Taylor, William Fuller, Marla J. Yazzie, Yudi Soesanto, Glendon J. Parker, Mark Hazel
Publikováno v:
Journal of Biological Chemistry. 283:6050-6057
O-Linked N-acetylglucosamine (O-GlcNAc) is a post-translational modification of proteins that functions as a nutrient sensing mechanism. Here we report on regulation of O-GlcNAcylation over a broad range of glucose concentrations. We have discovered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b4d9111de2fd93a8ce364c1db91a9b
https://doi.org/10.1074/jbc.m707328200
https://doi.org/10.1074/jbc.m707328200
Publikováno v:
Journal of Biological Chemistry. 279:20636-20642
Glycogen synthase is post-translationally modified by both phosphate and O-linked N-acetylglucosamine (O-GlcNAc). In 3T3-L1 adipocytes exposed to high concentrations of glucose, O-GlcNAc contributes to insulin resistance of glycogen synthase. We soug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bb500d97146fa64a0391cd398056291
https://doi.org/10.1074/jbc.m312139200
https://doi.org/10.1074/jbc.m312139200
Publikováno v:
Journal of Biological Chemistry. 278:10022-10027
We have investigated the mechanism by which high concentrations of glucose inhibit insulin stimulation of glycogen synthase. In NIH-3T3-L1 adipocytes cultured in low glucose (LG; 2.5 mm), the half-maximal activation concentration (A(0.5)) of glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00a33dcf7fed2839ff5b290a5621179
https://doi.org/10.1074/jbc.m207787200
https://doi.org/10.1074/jbc.m207787200
Autor:
Bai Luo, J. Scott Gabrielsen, Deborah Jones, Glendon J. Parker, Yudi Soesanto, Rodrick P. Taylor, Donald A. McClain
The hexosamine biosynthesis pathway (HBP) regulates the posttranslational modification of nuclear and cytoplasmic protein by O-linked N-acetylglucosamine ( O-GlcNAc). Numerous studies have demonstrated that, in hyperglycemic conditions, excessive glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f309c4400de71554039783ba2037fcc2
https://europepmc.org/articles/PMC2575895/
https://europepmc.org/articles/PMC2575895/
Publikováno v:
Diabetes; Jun2003 Supplement, Vol. 52, pA675-A730, 56p, 1 Chart