Zobrazeno 1 - 10
of 545
pro vyhledávání: '"Rodríguez-Sinovas A"'
Autor:
David Aluja, Sara Delgado-Tomás, Jose A. Barrabés, Elisabet Miró-Casas, Marisol Ruiz-Meana, Antonio Rodríguez-Sinovas, Begoña Benito, Jinxi Wang, Long-Sheng Song, Ignacio Ferreira-González, Javier Inserte
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110935- (2024)
Summary: Cysteine proteases calpains contribute to heart failure (HF), but it remains unknown whether their inhibition provides any benefit compared to standard pharmacological treatment for HF. Here, we characterize the pharmacological properties of
Externí odkaz:
https://doaj.org/article/aa17149d910f495a8019f1ee9514b55b
Autor:
Aluja, David, Delgado-Tomás, Sara, Barrabés, Jose A., Miró-Casas, Elisabet, Ruiz-Meana, Marisol, Rodríguez-Sinovas, Antonio, Benito, Begoña, Wang, Jinxi, Song, Long-Sheng, Ferreira-González, Ignacio, Inserte, Javier
Publikováno v:
In iScience 18 October 2024 27(10)
Autor:
Gabriel Jakobsson, Praveen Papareddy, Henrik Andersson, Megan Mulholland, Ravi Bhongir, Irena Ljungcrantz, Daniel Engelbertsen, Harry Björkbacka, Jan Nilsson, Adrian Manea, Heiko Herwald, Marisol Ruiz-Meana, Antonio Rodríguez-Sinovas, Michelle Chew, Alexandru Schiopu
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-16 (2023)
Abstract Background and Aims The triggering factors of sepsis-induced myocardial dysfunction (SIMD) are poorly understood and are not addressed by current treatments. S100A8/A9 is a pro-inflammatory alarmin abundantly secreted by activated neutrophil
Externí odkaz:
https://doaj.org/article/f78a88129a0f43719448e956af50193c
Autor:
Lídia Puertas-Umbert, Saray Varona, Carme Ballester-Servera, Judith Alonso, Silvia Aguiló, Mar Orriols, Ernesto Martínez-Martínez, Antonio Rodríguez-Sinovas, José Martínez-González, Cristina Rodríguez
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 639-642 (2023)
Externí odkaz:
https://doaj.org/article/9cdd1bceae394f07acdd3e83cd20720c
Autor:
Carme Ballester-Servera, Judith Alonso, Laia Cañes, Paula Vázquez-Sufuentes, Lídia Puertas-Umbert, Amaya Fernández-Celis, Manel Taurón, Antonio Rodríguez-Sinovas, Natalia López-Andrés, Cristina Rodríguez, José Martínez-González
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115469- (2023)
Extracellular matrix (ECM) is an active player in cardiovascular calcification (CVC), a major public health issue with an unmet need for effective therapies. Lysyl oxidase (LOX) conditions ECM biomechanical properties; thus, we hypothesized that LOX
Externí odkaz:
https://doaj.org/article/f223b753541d45cab74884dcd8ab2643
Autor:
Ballester-Servera, Carme, Alonso, Judith, Cañes, Laia, Vázquez-Sufuentes, Paula, Puertas-Umbert, Lídia, Fernández-Celis, Amaya, Taurón, Manel, Rodríguez-Sinovas, Antonio, López-Andrés, Natalia, Rodríguez, Cristina, Martínez-González, José
Publikováno v:
In Biomedicine & Pharmacotherapy November 2023 167
Autor:
Marta Consegal, Ignasi Barba, Bruno García del Blanco, Imanol Otaegui, José F. Rodríguez-Palomares, Gerard Martí, Bernat Serra, Neus Bellera, Manuel Ojeda-Ramos, Filipa Valente, Maria Ángeles Carmona, Elisabet Miró-Casas, Antonia Sambola, Rosa María Lidón, Jordi Bañeras, José Antonio Barrabés, Cristina Rodríguez, Begoña Benito, Marisol Ruiz-Meana, Javier Inserte, Ignacio Ferreira-González, Antonio Rodríguez-Sinovas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Succinate is enhanced during initial reperfusion in blood from the coronary sinus in ST-segment elevation myocardial infarction (STEMI) patients and in pigs submitted to transient coronary occlusion. Succinate levels might have a prognostic
Externí odkaz:
https://doaj.org/article/6643e3d444344302890ed52ff655574b
Autor:
Laura Valls-Lacalle, Marta Consegal, Freddy G. Ganse, Laia Yáñez-Bisbe, Javier Pastor, Marisol Ruiz-Meana, Javier Inserte, Begoña Benito, Ignacio Ferreira-González, Antonio Rodríguez-Sinovas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4366 (2024)
Succinate dehydrogenase inhibition with malonate during initial reperfusion reduces myocardial infarct size in both isolated mouse hearts subjected to global ischemia and in in situ pig hearts subjected to transient coronary ligature. However, the lo
Externí odkaz:
https://doaj.org/article/8490184789814664942df26ad31fedbe
Akademický článek
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Autor:
Laia Yáñez-Bisbe, Mar Moya, Antonio Rodríguez-Sinovas, Marisol Ruiz-Meana, Javier Inserte, Marta Tajes, Montserrat Batlle, Eduard Guasch, Aleksandra Mas-Stachurska, Elisabet Miró, Nuria Rivas, Ignacio Ferreira González, Anna Garcia-Elias, Begoña Benito
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1541 (2024)
TRPV4 channels, which respond to mechanical activation by permeating Ca2+ into the cell, may play a pivotal role in cardiac remodeling during cardiac overload. Our study aimed to investigate TRPV4 involvement in pathological and physiological remodel
Externí odkaz:
https://doaj.org/article/8d0d2e6ac1ca4c28b16f11b375971ae5