Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Rodolpho C Braga"'
Autor:
Bruno J Neves, Rodolpho C Braga, Vinicius M Alves, Marília N N Lima, Gustavo C Cassiano, Eugene N Muratov, Fabio T M Costa, Carolina Horta Andrade
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 2, p e1007025 (2020)
Malaria is an infectious disease that affects over 216 million people worldwide, killing over 445,000 patients annually. Due to the constant emergence of parasitic resistance to the current antimalarial drugs, the discovery of new drug candidates is
Externí odkaz:
https://doaj.org/article/9db59f29aff44242bd02821ded76b5c5
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 1, p e3435 (2015)
Morbidity and mortality caused by schistosomiasis are serious public health problems in developing countries. Because praziquantel is the only drug in therapeutic use, the risk of drug resistance is a concern. In the search for new schistosomicidal d
Externí odkaz:
https://doaj.org/article/2da02339d91d4fb483b590ad5f679ffc
Autor:
José T. Moreira-Filho, Rodolpho C. Braga, Jade Milhomem Lemos, Vinicius M. Alves, Joyce V.V.B. Borba, Wesley S. Costa, Nicole Kleinstreuer, Eugene N. Muratov, Carolina Horta Andrade, Bruno J. Neves
Publikováno v:
Artificial Intelligence in the Life Sciences, Vol 1, Iss , Pp 100013- (2021)
Chemically induced toxicity is the leading cause of recent extinction of honey bees. In this regard, we developed an innovative artificial intelligence-based web app (BeeToxAI) for assessing the acute toxicity of chemicals to Apis mellifera. Initiall
Externí odkaz:
https://doaj.org/article/59a44a6d504f4ad5a3edf955f3796145
Autor:
Vinicius M Alves, Joyce V B Borba, Rodolpho C Braga, Daniel R Korn, Nicole Kleinstreuer, Kevin Causey, Alexander Tropsha, Diego Rua, Eugene N Muratov
Publikováno v:
Toxicological Sciences. 189:250-259
In the United States, a pre-market regulatory submission for any medical device that comes into contact with either a patient or the clinical practitioner must include an adequate toxicity evaluation of chemical substances that can be released from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b113c1a12bf4444b824bf83640b5e985
https://doi.org/10.1093/toxsci/kfac078
https://doi.org/10.1093/toxsci/kfac078
Autor:
Bruno J. Neves, Rodolpho C. Braga, Cleber C. Melo-Filho, José Teófilo Moreira-Filho, Eugene N. Muratov, Carolina Horta Andrade
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Virtual screening (VS) has emerged in drug discovery as a powerful computational approach to screen large libraries of small molecules for new hits with desired properties that can then be tested experimentally. Similar to other computational approac
Externí odkaz:
https://doaj.org/article/5434a00ab8f94cd9ba56f3f898f63730
Autor:
Joyce V B, Borba, Vinicius M, Alves, Rodolpho C, Braga, Daniel R, Korn, Kirsten, Overdahl, Arthur C, Silva, Steven U S, Hall, Erik, Overdahl, Nicole, Kleinstreuer, Judy, Strickland, David, Allen, Carolina Horta, Andrade, Eugene N, Muratov, Alexander, Tropsha
Publikováno v:
Environmental health perspectives. 130(2)
Modern chemical toxicology is facing a growing need to Reduce, Refine, and Replace animal tests (Russell 1959) for hazard identification. The most common type of animal assays for acute toxicity assessment of chemicals used as pesticides, pharmaceuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51dd5b03bd93a1ed610b67ddd698ad64
https://pubmed.ncbi.nlm.nih.gov/35192406
https://pubmed.ncbi.nlm.nih.gov/35192406
Autor:
Joyce V.B. Borba, Vinicius M. Alves, Rodolpho C. Braga, Daniel R. Korn, Kirsten Overdahl, Arthur C. Silva, Steven U.S. Hall, Erik Overdahl, Nicole Kleinstreuer, Judy Strickland, David Allen, Carolina Horta Andrade, Eugene N. Muratov, Alexander Tropsha
Publikováno v:
Environmental Health Perspectives. 130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f0f136bafd0b592783ce92e58d0a5f9
https://doi.org/10.1289/ehp9341
https://doi.org/10.1289/ehp9341
Autor:
Carolina Horta Andrade, Wesley S. Costa, José T. Moreira-Filho, Nicole Kleinstreuer, Jade Milhomem Lemos, Vinicius M. Alves, Bruno J. Neves, Rodolpho C. Braga, Joyce V. V. B. Borba, Eugene N. Muratov
Publikováno v:
Artificial Intelligence in the Life Sciences, Vol 1, Iss, Pp 100013-(2021)
Chemically induced toxicity is the leading cause of recent extinction of honey bees. In this regard, we developed an innovative artificial intelligence-based web app (BeeToxAI) for assessing the acute toxicity of chemicals to Apis mellifera. Initiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a3d80d8ad5f685bc34e6fdaf761fc5
http://www.sciencedirect.com/science/article/pii/S2667318521000131
http://www.sciencedirect.com/science/article/pii/S2667318521000131
Autor:
Paulo Sérgio Taube, Rodolpho C. Braga, Kauê Santana da Costa, João Marcos Pereira Galúcio, Clauber Henrique Souza da Costa, Élcio Leal
Publikováno v:
Anais do I Congresso de Engenharia de Biotecnologia.
Introdução: O Nipah (NiV) é um vírus zoonótico emergente pertencente à família Paramyxoviridae que está envolvido com doenças respiratórias e neurológicas fatais em humanos. O NiV representa um desafio para a saúde pública com o risco po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6e6e05bc83518b14ed4c7d8dcfabaf8
https://doi.org/10.51189/rema/1388
https://doi.org/10.51189/rema/1388
Autor:
Bruno J. Neves, Carolina Horta Andrade, Cleber C. Melo-Filho, Juliana Rodrigues, Rodolpho C. Braga, Pedro Cravo, Diego Cabral Silva
Publikováno v:
Current Medicinal Chemistry. 26:4355-4379
Only ~1% of all drug candidates against Neglected Tropical Diseases (NTDs) have reached clinical trials in the last decades, underscoring the need for new, safe and effective treatments. In such context, drug repositioning, which allows finding novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e669b6e95e733eb4d247b52f56480ff2
https://doi.org/10.2174/0929867325666180309114824
https://doi.org/10.2174/0929867325666180309114824