Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rodolphe Vatinel"'
Autor:
Loïc Tomas, Rodolphe Vatinel, Craig S. Harris, Veronique Parnet, Gilles Ouvry, Catherine Raffin, Bénédicte Drean, Claire Bouix-Peter, Kana Kunihiro, Guillaume Lafitte, Branislav Musicki, Jean-François Fournier, Frédéric Gaigne, Romain Pierre, Céline Bonneaud
Publikováno v:
Tetrahedron Letters. 58:3757-3759
The preparation of the boroxole motif traditionally relies on a 3-step process and the use of n -butyl lithium that can limit substrate scope. Herein during our exploration toward novel RORγ inhibitors, we identified a convenient one-pot preparation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::391ca91636278c61a11cf3907054cbb2
https://doi.org/10.1016/j.tetlet.2017.08.011
https://doi.org/10.1016/j.tetlet.2017.08.011
Autor:
Etienne Thoreau, Craig S. Harris, David Froude, Franck Bihl, Gilles Ouvry, Delphine Spiesse, Patricia Rossio, Christophe Feret, Emmanuel Vial, Laurent F. Hennequin, Jonathan Pascau, Coralie Pascau, Romain Pierre, Claire Defoin-Platel, Nathalie Taquet, Catherine Hervouet, Veronique Parnet, Olivier Christin, Guillaume Lafitte, Sophie Deret, Catherine Raffin, Claire Bouix-Peter, Anne-Pascale Luzy, Feriel Hacini-Rachinel, Branislav Musicki, Danielle Orfila, Rodolphe Vatinel
Publikováno v:
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, 2018, 28 (8), pp.1269-1273. ⟨10.1016/j.bmcl.2018.03.041⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2018, 28 (8), pp.1269-1273. ⟨10.1016/j.bmcl.2018.03.041⟩
Bioorganic and Medicinal Chemistry Letters, 2018, 28 (8), pp.1269-1273. ⟨10.1016/j.bmcl.2018.03.041⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2018, 28 (8), pp.1269-1273. ⟨10.1016/j.bmcl.2018.03.041⟩
Progress in the identification of suitable RORγ inverse agonists as clinical candidates has been hampered by the high lipophilicity that seems required for high potency on this nuclear receptor. In this context, we decided to focus on the replacemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fa57781e16cd4033a4b4d8d851561b
https://hal.science/hal-02526180
https://hal.science/hal-02526180
Autor:
Coralie Pascau, Nicolas Atrux-Tallau, Laurent F. Hennequin, Christophe Feret, Gilles Ouvry, Feriel Hacini-Rachinel, Craig S. Harris, Claire Defoin-Platel, Nathalie Taquet, Sophie Deret, Mathieu Forissier, Hélène Huguet, Etienne Thoreau, Benjamin Ozello, Olivier Christin, Emmanuel Vial, Guillaume Lafitte, Danielle Orfila, Isabelle Carlavan, Franck Bihl, David Froude, Jean-François Fournier, Denis Duvert, Anne-Pascale Luzy, Delphine Spiesse, Patricia Rossio, Marie-Josée Cuadrado, Jonathan Pascau, Catherine Raffin, Aline Bondu, Claire Bouix-Peter, Catherine Hervouet, Guillaume Peluchon, Veronique Parnet, David Piwnica, Branislav Musicki, Rodolphe Vatinel, Romain Pierre
Publikováno v:
ChemMedChem
ChemMedChem, 2018, 13 (4), pp.321-337. ⟨10.1002/cmdc.201700758⟩
ChemMedChem, Wiley-VCH Verlag, 2018, 13 (4), pp.321-337. ⟨10.1002/cmdc.201700758⟩
ChemMedChem, 2018, 13 (4), pp.321-337. ⟨10.1002/cmdc.201700758⟩
ChemMedChem, Wiley-VCH Verlag, 2018, 13 (4), pp.321-337. ⟨10.1002/cmdc.201700758⟩
With possible implications in multiple autoimmune diseases, the retinoic acid receptor-related orphan receptor RORγ has become a sought-after target in the pharmaceutical industry. Herein are described the efforts to identify a potent RORγ inverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad689ccdeaf5f01fb20f8a6ff41d3b4a
https://hal.science/hal-02526191
https://hal.science/hal-02526191