Výsledky vyhledávání - "Rodolphe Roggero"

Automated Monitoring of Phosphatidylcholine Biosyntheses in Plasmodium falciparum by Electrospray Ionization Mass Spectrometry through Stable Isotope Labeling Experiments

Autor: Jean-Louis Aubagnac, Jean Martinez, Rachel Cerdan, Christine Enjalbal, Henri Vial, Rodolphe Roggero

Publikováno v: Analytical Chemistry. 76:4515-4521

The metabolic pathways contributing to phosphatidylcholine biosyntheses in Plasmodium falciparum, the malaria-causing parasite, was explored by electrospray ionization mass spectrometry. Phosphatidylcholine produced by the CDP-choline pathway and by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03af6ddf6296cad9f60b04fb64365034
https://doi.org/10.1021/ac049759+

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Binding of Human Immunodeficiency Virus Type 1 gp120 to CXCR4 Induces Mitochondrial Transmembrane Depolarization and Cytochromec-Mediated Apoptosis Independently of Fas Signaling

Autor: Christian Devaux, Martine Biard-Piechaczyk, Rodolphe Roggero, Véronique Robert-Hebmann, Sara Jaleco, Steve Harrington, Joachim Roland, Laurence Vergne

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2001, 75 (16), pp.7637--7650

Apoptosis of CD4+T lymphocytes, induced by contact between human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (gp120) and its receptors, could contribute to the cell depletion observed in HIV-infected individuals. CXCR4 appears to play

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e7d232dfd78238f1b5807f778c8da6
https://doi.org/10.1128/jvi.75.16.7637-7650.2001

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Unraveling the mode of action of the antimalarial choline analog G25 in Plasmodium falciparum and Saccharomyces cerevisiae

Autor: Eric Richier, Michèle Calas, Henri Vial, Mihaela Minca, Rachel Zufferey, Choukri Ben Mamoun, Rodolphe Roggero

Publikováno v: Antimicrobial agents and chemotherapy. 48(8)

Pharmacological studies have indicated that the choline analog G25 is a potent inhibitor of Plasmodium falciparum growth in vitro and in vivo. Although choline transport has been suggested to be the target of G25, the exact mode of action of this com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075545cf9a17713b3c42b1a6ad0a8915
https://pubmed.ncbi.nlm.nih.gov/15273086

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