Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Rodolphe Perrot"'
Autor:
Norraseth Kaeokhamloed, Emillie Roger, Jérôme Béjaud, Nolwenn Lautram, Florence Manero, Rodolphe Perrot, Marie Briet, Chadi Abbara, Samuel Legeay
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 595 (2021)
Standard models used for evaluating the absorption of nanoparticles like Caco-2 ignore the presence of vascular endothelium, which is a part of the intestinal multi-layered barrier structure. Therefore, a coculture between the Caco-2 epithelium and H
Externí odkaz:
https://doaj.org/article/d205ce3c2445475c8ccc39dac900cb2c
Autor:
Rodolphe Perrot, Jean-Jacques Helesbeux, Denis Séraphin, Marie Kempf, Pascal Richomme, Khaled Alsabil, Guillaume Viault, Alexia Ville
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (5), pp.881-890. ⟨10.1002/cmdc.202000792⟩
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (5), pp.881-890. ⟨10.1002/cmdc.202000792⟩
New 5-substituted vitamin E derivatives were semisynthesized, and their antibacterial activity against human Gram-positive and Gram-negative pathogens was evaluated. Several vitamin E analogues were active against methicillin-resistant Staphylococcus
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance
Autor:
Jade Aurrière, David Goudenege, Simone A. Baechler, Shar-Yin N. Huang, Naig Gueguen, Valerie Desquiret-Dumas, Floris Chabrun, Rodolphe Perrot, Arnaud Chevrollier, Majida Charif, Olivier R Baris, Yves Pommier, Guy Lenaers, Salim Khiati
Publikováno v:
Mitochondrion
Cancer/Testis Antigens (CTAs) represent a group of proteins whose expression under physiological conditions is restricted to testis but activated in many human cancers. Also, it was observed that co-expression of multiple CTAs worsens the patient pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4445dd0759229db7bb393ef2f5aad4df
https://europepmc.org/articles/PMC9057655/
https://europepmc.org/articles/PMC9057655/
Publikováno v:
Microscopy Research and Technique. 82:2072-2078
Death of osteocytes is synonymous of bone death. Aseptic osteonecrosis of the femoral head is a lesion characterized by the death of osteocytes occurring after major vascular changes. The evolution may lead to hip osteoarthritis, which requires total
Autor:
Franck Geneviève, Marion Pitorre, Jean-Pierre Benoit, Valérie Moal, Karolina Frankova, Nolwenn Lautram, Rodolphe Perrot, Jérôme Bejaud, Claire Gazaille, Jérémie Riou, Le Thuy Trang Pham, Guillaume Bastiat
Publikováno v:
Materials Science and Engineering: C
Materials Science and Engineering: C, Elsevier, 2021, 126, pp.112188. ⟨10.1016/j.msec.2021.112188⟩
Materials Science and Engineering: C, Elsevier, 2021, 126, pp.112188. ⟨10.1016/j.msec.2021.112188⟩
Nanoparticle-loaded hydrogels are attractive pharmaceutical drug delivery systems that combine the advantages of both hydrogel (local administration and/or sustained drug release) and nanoparticle (stealthiness, targeting and decreased toxicity). The
Autor:
Philippe Menei, Laurence Sindji, Maximiliano Luis Cacicedo, Claudia N. Montero-Menei, Florence Franconi, Guillermo R. Castro, Audrey Rousseau, Lila Autier, Anne Clavreul, Rodolphe Perrot
Publikováno v:
Acta Biomaterialia
Acta Biomaterialia, 2019, ⟨10.1016/j.actbio.2018.11.027⟩
Acta Biomaterialia, Elsevier, 2019, ⟨10.1016/j.actbio.2018.11.027⟩
Acta Biomaterialia, 2019, ⟨10.1016/j.actbio.2018.11.027⟩
Acta Biomaterialia, Elsevier, 2019, ⟨10.1016/j.actbio.2018.11.027⟩
Glioblastoma (GB) is a highly infiltrative tumor, recurring, in 90% of cases, within a few centimeters of the surgical resection cavity, even with adjuvant chemo/radiotherapy. Residual GB cells left in the margins or infiltrating the brain parenchyma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529570ca8fb49cbda77155f7c2ebc490
https://www.sciencedirect.com/science/article/abs/pii/S1742706118306810
https://www.sciencedirect.com/science/article/abs/pii/S1742706118306810
Publikováno v:
BONE
BONE, Elsevier, 2016, 90, pp.99-106. ⟨10.1016/j.bone.2016.06.008⟩
BONE, Elsevier, 2016, 90, pp.99-106. ⟨10.1016/j.bone.2016.06.008⟩
International audience; Diabetes mellitus is considered to be an independent risk factor for bone fragility fractures. Reductions in bone mass, observed only with type 1 diabetes mellitus, as well as modifications of bone microarchitectures and tissu
Publikováno v:
Journal of endocrinology
Journal of endocrinology, 2018, 239 (2), pp.215-227. ⟨10.1530/JOE-18-0214⟩
Journal of endocrinology, 2018, 239 (2), pp.215-227. ⟨10.1530/JOE-18-0214⟩
Glucose-dependent insulinotropic polypeptide (GIP) has been recognized in the last decade as an important contributor of bone remodelling and is necessary for optimal bone quality. However, GIP receptors are expressed in several tissues in the body a
Autor:
Valérie Desquiret-Dumas, Stéphanie Chupin, Rodolphe Perrot, Naïg Gueguen, Dominique Bonneau, David C. Logan, Ilaria Dalla Rosa, Vincent Procaccio, David Goudenège, Jamal Wakim, Morgane Le Mao, Guy Lenaers, Juan Manuel Chao de la Barca, Pascal Reynier, Florence Manero, Salim Khiati, Arnaud Chevrollier
Publikováno v:
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2017, 130 (11), pp.1940-1951. ⟨10.1242/jcs.201616⟩
Journal of Cell Science, Company of Biologists, 2017, 130 (11), pp.1940-1951. ⟨10.1242/jcs.201616⟩
Mitochondrial dynamics and distribution are critical for supplying ATP in response to energy demand. CLUH is a protein involved in mitochondrial distribution whose dysfunction leads to mitochondrial clustering, the metabolic consequences of which rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03a48acb56ac1fd1027af21d6d69708
https://hal.archives-ouvertes.fr/hal-01601889
https://hal.archives-ouvertes.fr/hal-01601889
Autor:
Alessandro Didonna, Saleemulla Mahammad, Boris Grin, Jean-Pierre Julien, Edward R. Kuczmarski, Pascale Bomont, S. N. Prasanna Murthy, Robert D. Goldman, Rodolphe Perrot, Eitan Israeli, Puneet Opal
Publikováno v:
Journal of Clinical Investigation. 123:1964-1975
Giant axonal neuropathy (GAN) is an early-onset neurological disorder caused by mutations in the GAN gene (encoding for gigaxonin), which is predicted to be an E3 ligase adaptor. In GAN, aggregates of intermediate filaments (IFs) represent the main p