Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rodolphe Besancenot"'
Autor:
Rodolphe Besancenot, Ronan Chaligné, Carole Tonetti, Florence Pasquier, Caroline Marty, Yann Lécluse, William Vainchenker, Stefan N Constantinescu, Stéphane Giraudier
Publikováno v:
PLoS Biology, Vol 8, Iss 9 (2010)
Thrombopoietin (TPO) via signaling through its cognate receptor MPL is a key cytokine involved in the regulation of megakaryocyte differentiation leading to platelet production. Mature megakaryocytes are polyploid cells that have arrested DNA replica
Externí odkaz:
https://doaj.org/article/699000c55e93404f939b77a32cd5c850
Autor:
Nobutaka Fujii, Monika Wittner, Giovanni Barosi, Shinya Oishi, Fawzia Louache, Rodolphe Besancenot, Isabelle Plo, Yanyan Zhang, Eric Solary, William Vainchenker, Hadjer Abdelouahab, Vincent Ribrag
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2017, 8 (33), ⟨10.18632/oncotarget.10789⟩
Oncotarget, Impact journals, 2017, 8 (33), ⟨10.18632/oncotarget.10789⟩
// Hadjer Abdelouahab 1, 2, 3, 4 , Yanyan Zhang 1, 3, 4 , Monika Wittner 1, 3, 4 , Shinya Oishi 6 , Nobutaka Fujii 6 , Rodolphe Besancenot 1, 3, 4 , Isabelle Plo 1, 3, 4, 7, 8 , Vincent Ribrag 1, 3, 4 , Eric Solary 1, 3, 4 , William Vainchenker 1, 3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd6ab0480c4c5f4f373ef044f9c7f13
https://hal.archives-ouvertes.fr/hal-02380531
https://hal.archives-ouvertes.fr/hal-02380531
Autor:
Damien Roos-Weil, Philippe Rameau, Stéphane Giraudier, Florence Pasquier, Christophe Willekens, Eric Solary, Hadjer Abdelouahab, William Vainchenker, Rodolphe Besancenot, Stefan N. Constantinescu, Jean-Baptiste Micol, Carole Tonetti, Yann Lécluse, Catherine Lacout
Publikováno v:
Blood. 124:2104-2115
Megakaryopoiesis is a 2-step differentiation process, regulated by thrombopoietin (TPO), on binding to its cognate receptor myeloproliferative leukemia (MPL). This receptor associates with intracytoplasmic tyrosine kinases, essentially janus kinase 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd79a5a49bc1a4f4f182e8d2487ea99
https://doi.org/10.1182/blood-2014-03-559815
https://doi.org/10.1182/blood-2014-03-559815
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 197:395-406
Each day, 2x10(11) platelets are produced in the human body by a highly regulated mechanism. The biology of platelet formation is unique, as platelets arise from cytoplasmic fragmentation of their marrow precursor, the megakaryocyte (MK). MKs are gia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faae6d5a63d482847d6cbfa204761713
https://doi.org/10.1016/s0001-4079(19)31594-8
https://doi.org/10.1016/s0001-4079(19)31594-8
Autor:
Alexandra Dusa, Pierre J. Courtoy, Stefan N. Constantinescu, Stéphane Giraudier, Rodolphe Besancenot, Judith Staerk, Laurent Knoops, Michael Girardot, Christian Pecquet, William Vainchenker, Carmen C. Diaconu, Yohan Royer, Caroline Marty, Jean-Philippe Defour, Jean-Luc Villeval
Publikováno v:
Blood. 119:4625-4635
The constitutively active JAK2 V617F mutant is the major determinant of human myeloproliferative neoplasms (MPNs). We show that coexpression of murine JAK2 V617F and the murine thrombopoietin (Tpo) receptor (TpoR, c-MPL) in hematopoietic cell lines o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68aaf903c4c0fc4bdad33a81de9e3d28
https://doi.org/10.1182/blood-2011-08-372524
https://doi.org/10.1182/blood-2011-08-372524
Publikováno v:
Revue Francophone des Laboratoires. 2011:41-46
Resume Les syndromes myeloproliferatifs classiques (polyglobulie de Vaquez, thrombocytemie essentielle et myelofibrose primitive, sont des pathologies clonales caracterisees par une production excessive de cellules myeloides matures. La parente entre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bc887e5fdbfcee8de770352dbb0bf97
https://doi.org/10.1016/s1773-035x(11)71003-6
https://doi.org/10.1016/s1773-035x(11)71003-6
Autor:
Frédéric Mazurier, Ronan Chaligne, Frédéric Larbret, Jean Pierre Le Couédic, Yann Lécluse, Stéphane Giraudier, Rodolphe Besancenot, Chloé James, Fanny Fava, William Vainchenker, Karim Maloum, Carole Tonetti, Isabelle Godin
Publikováno v:
Blood. 110:3735-3743
The MPL (W515L and W515K) mutations have been detected in granulocytes of patients suffering from certain types of primitive myelofibrosis (PMF). It is still unknown whether this molecular event is also present in lymphoid cells and therefore potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31d2a169a888152cefd795cd83bbd59
https://doi.org/10.1182/blood-2007-05-089003
https://doi.org/10.1182/blood-2007-05-089003
Publikováno v:
Bulletin de l'Academie nationale de medecine. 197(2)
Each day, 2x10(11) platelets are produced in the human body by a highly regulated mechanism. The biology of platelet formation is unique, as platelets arise from cytoplasmic fragmentation of their marrow precursor, the megakaryocyte (MK). MKs are gia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91a0b7f95067089fe5b9acd41145bd64
https://pubmed.ncbi.nlm.nih.gov/24919369
https://pubmed.ncbi.nlm.nih.gov/24919369
Autor:
William Vainchenker, Caroline Marty, Rodolphe Besancenot, Stéphane Giraudier, Yann Lécluse, Ronan Chaligne, Florence Pasquier, Carole Tonetti, Stefan N. Constantinescu
Publikováno v:
PLoS Biology
PLoS Biology, Public Library of Science, 2010, 8 (9), epub ahead of print. ⟨10.1371/journal.pbio.1000476⟩
PLoS Biology, 2010, 8 (9), epub ahead of print. ⟨10.1371/journal.pbio.1000476⟩
PLoS Biology, Vol. 8, no.9, p. 0 (2010)
PLoS Biology, Vol 8, Iss 9 (2010)
PLoS Biology, Public Library of Science, 2010, 8 (9), epub ahead of print. ⟨10.1371/journal.pbio.1000476⟩
PLoS Biology, 2010, 8 (9), epub ahead of print. ⟨10.1371/journal.pbio.1000476⟩
PLoS Biology, Vol. 8, no.9, p. 0 (2010)
PLoS Biology, Vol 8, Iss 9 (2010)
During normal megakaryocyte development, in response to thrombopoetin, mature cells enter a senescence-like state in which they shed platelets; this state, characterized by cell cycle arrest, is defective in malignant megakaryocytes.
Thrombopoie
Thrombopoie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bf34176d8ddac6a89c2c926dc893e7
https://www.hal.inserm.fr/inserm-00707240/file/journal.pbio.1000476.pdf
https://www.hal.inserm.fr/inserm-00707240/file/journal.pbio.1000476.pdf
Autor:
Stéphane Giraudier, Carole Tonetti, Jean-Jacques Kiladjian, Rodolphe Besancenot, Gérard Socié, Dominique Bordessoule, Ronan Chaligne, William Vainchenker, Caroline Marty
Publikováno v:
Leukemia
Leukemia, 2009, 23 (6), pp.1186-90. ⟨10.1038/leu.2009.22⟩
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2009, 23 (6), pp.1186-90. ⟨10.1038/leu.2009.22⟩
Leukemia, 2009, 23 (6), pp.1186-90. ⟨10.1038/leu.2009.22⟩
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2009, 23 (6), pp.1186-90. ⟨10.1038/leu.2009.22⟩
SOCS3 inhibits TPO-stimulated, but not spontaneous, megakaryocytic growth in primary myelofibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43a0976e71a7b0bc8ff02968a71d618
https://hal.archives-ouvertes.fr/hal-00453235
https://hal.archives-ouvertes.fr/hal-00453235