Tocilizumab versus anakinra in COVID-19: results from propensity score matching

Autor: Robin Arcani, Florian Correard, Pierre Suchon, Gilles Kaplanski, Rodolphe Jean, Raphael Cauchois, Marine Leprince, Vincent Arcani, Julie Seguier, Benjamin De Sainte Marie, Baptiste Andre, Marie Koubi, Pascal Rossi, Stéphane Gayet, Nirvina Gobin, Victoria Garrido, Joris Weiland, Elisabeth Jouve, Anne-Laure Couderc, Patrick Villani, Aurélie Daumas

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundTocilizumab and anakinra are anti-interleukin drugs to treat severe coronavirus disease 2019 (COVID-19) refractory to corticosteroids. However, no studies compared the efficacy of tocilizumab versus anakinra to guide the choice of the thera

Externí odkaz: https://doaj.org/article/4fc10343fb484f138e16cd6442659fb8

Aortitis is an under-recognized manifestation of antiphospholipid syndrome: A case report and literature review

Autor: Thomas Escoda, Julia George, Pierre-André Jarrot, Rodolphe Jean, Karin Mazodier, Frederick Sanderson, Pascale Poullin, Ludivine Saby, Noémie Jourde-Chiche, Gilles Kaplanski, Laurent Chiche

Publikováno v: Lupus. 31:744-753

Aortitis is a classic manifestation of large vessel vasculitis. Antiphospholipid syndrome (APS), sometimes known as Hughes syndrome, is an acquired autoimmune disorder that manifests clinically as recurrent venous or arterial thrombosis. Patients wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f5a3667681179b9825b4f62cba1b53
https://doi.org/10.1177/09612033221091142

Clinical characteristics and outcomes of patients with haematologic malignancies and COVID-19 suggest that prolonged SARS-CoV-2 carriage is an important issue

Autor: Régis Costello, J Colle, Raphael Cauchois, Gilles Kaplanski, Pierre-André Jarrot, Anne-Laure Couderc, Julie Lachamp, Rodolphe Jean, Antoine Tichadou, Geoffroy Venton, Arthur Boyer, Robin Arcani, Laure Farnault, Marie Koubi

Publikováno v: Annals of Hematology
Annals of Hematology, 2021, 100 (11), pp.2799-2803. ⟨10.1007/s00277-021-04656-z⟩

Specificities of COVID-19 disease course in patients with haematologic malignancies are still poorly studied. So, we aimed to compare patients with haematologic malignancies to patients without malignancies, matched by sex and age and hospitalised fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db594c32fefd8d8fedc30ea450578b7
https://doi.org/10.1007/s00277-021-04656-z

Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

Autor: Raphael Cauchois, Karin Mazodier, Valery Benjamin Blasco, David Delarbre, Marie Koubi, Vincent Pestre, Pierre André Jarrot, Cecile Manet, Julien Carvelli, Louis Fouche, Charleric Bornet, Charles A. Dinarello, Gilles Kaplanski, Rodolphe Jean, Vanessa Pauly

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences USA, 117, 18951-18953
Proceedings of the National Academy of Sciences USA, 117, 32, pp. 18951-18953

Around the tenth day after diagnosis, ∼20% of patients with coronavirus disease 2019 (COVID-19)−associated pneumonia evolve toward severe oxygen dependence (stage 2b) and acute respiratory distress syndrome (stage 3) associated with systemic infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67891f485ec171bbbcad87a111c8e541
http://europepmc.org/articles/PMC7430998

Syndrome catastrophique des antiphospholipides traité par éculizumab : à propos de deux cas

Autor: Karin Mazodier, Gilles Kaplanski, A. Le Roux, Rodolphe Jean, V. Roumieu, R. Cauchois

Publikováno v: La Revue de Médecine Interne. 42:A356-A357

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80034397891af717536f884b92e40b3b
https://doi.org/10.1016/j.revmed.2021.10.028