Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rodney L. Robison"'
Publikováno v:
Toxicology. 101:157-166
The tolerability and potential target organ toxicity of rhIL-6 administered subcutaneously (s.c.) with rhGM-CSF or rhG-CSF were investigated in healthy nonhuman primates. Fifteen Rhesus monkeys were randomized to receive one of the following five reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de66605fbb6ab26d62a645569927cf03
https://doi.org/10.1016/0300-483x(95)03081-p
https://doi.org/10.1016/0300-483x(95)03081-p
Autor:
Suzanne R. Thornton, Kenneth D. Nitschke, Wendy K. Sherman, David A. Penney, Raymond E. Schroeder, Dean E. Rodwell, Rodney L. Robison
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 68(1)
Vinyl chloride (VC) exposure is primarily via inhalation in the workplace. The primary target organ of VC toxicity is the liver and occupational exposure to VC leads to hepatic angiosarcoma. However, based on epidemiological studies, researchers have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c85d0df7d6dd88536edf5c73f42da9e
https://pubmed.ncbi.nlm.nih.gov/12075123
https://pubmed.ncbi.nlm.nih.gov/12075123
Publikováno v:
Toxicologic pathology. 25(3)
A rare spontaneous tumor was detected in the kidney of an 11-mo-old beagle dog. The tumor was a well-circumscribed cortical mass and was composed of a heterogeneous population of connective tissue cell types. While the primary cell type was a spindle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d366abde05483097faf3c2fe6d841a
https://pubmed.ncbi.nlm.nih.gov/9210265
https://pubmed.ncbi.nlm.nih.gov/9210265
Autor:
Laurie A. Myers, Howard A. Hartman, Morton Evans, Robert G. Engstrom, Francis L. S. Tse, Rodney L. Robison
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 29(1)
Fluvastatin is a potent synthetic competitive inhibitor of beta-hydroxy-beta-methyl-glutaryl-coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme in the biosynthetic pathway for hepatic cholesterol synthesis. The therapeutic indication is reducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca87bd125e601081eb61f53fd2b4a19
https://pubmed.ncbi.nlm.nih.gov/8838639
https://pubmed.ncbi.nlm.nih.gov/8838639
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 23(1)
The HMG-CoA reductase inhibitors are a new and novel class of cholesterol-lowering agents which are widely used worldwide. Fluvastatin is the first entirely synthetic compound in this class and is structurally distinct from fungal metabolite derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48919bb941dac60f555b2e6348fe40ac
https://pubmed.ncbi.nlm.nih.gov/7958569
https://pubmed.ncbi.nlm.nih.gov/7958569
Autor:
Robert J. Van Ryzin, Robert E. Bagdon, Raymond E. Stoll, Rodney L. Robison, Richard D. Jensen
Publikováno v:
Fundamental and Applied Toxicology. 4:394-405
The benzodiazepine temazepam was given to Charles River CD rats for 2 years in the diet at dosages of 10, 40, and 160 mg/kg day. An 18-month study was performed in Charles River CD-1 mice via dietary admixture at dosages of 10, 80, and 160 mg/kg/day.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7cae29689366242a5ec8bb2b91d887a
https://doi.org/10.1016/0272-0590(84)90197-0
https://doi.org/10.1016/0272-0590(84)90197-0
Autor:
George E. Visscher, Rodney L. Robison
Publikováno v:
The Bulletin of the Society of Pharmacological and Environmental Pathologists. 6:7-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9bf9410c2abcb656cd416870a2ab47f
https://doi.org/10.1177/019262337800600204
https://doi.org/10.1177/019262337800600204
Autor:
George E. Visscher, Robert G. Engstrom, Howard A. Hartman, Stanley A. Roberts, Frances H. Ballard, Rodney L. Robison
Publikováno v:
Toxicologic pathology. 13(4)
Numerous amphiphilic cationic drugs cause generalized phospholipidosis in animals; one of these drugs is the Sandoz compound 200–125, a psychotropic agent. During a 6-month toxicity study in Charles River CD rats, a dramatic increase in foamy macro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c631756a5e59e1d9542f4b46652181
https://pubmed.ncbi.nlm.nih.gov/3834585
https://pubmed.ncbi.nlm.nih.gov/3834585