Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Rodney E, Phillips"'
Autor:
John Frater, Luke A. Granger, Jonathan Weber, Giuseppe Tambussi, David A. Cooper, José M. Miró, Martin Fisher, Gita Ramjee, Isabella Huettner, Julie Fox, Abdel Babiker, Sarah Fidler, Pontiano Kaleebu, Katie J. Doores, Rodney E. Phillips, Franka Debeljak, Mauro Schechter
Publikováno v:
AIDS (London, England)
OBJECTIVE: Development of immunogens that elicit an anti-HIV-1 broadly neutralizing antibody (bnAb) response will be a key step in the development of an effective HIV-1 vaccine. Although HIV-1 bnAb epitopes have been identified and mechanisms of acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0199d9b820b892fbab475f16c31cb00
http://hdl.handle.net/10044/1/101938
http://hdl.handle.net/10044/1/101938
Autor:
Hannah E Roberts, Jacob Hurst, Nicola Robinson, Helen Brown, Peter Flanagan, Laura Vass, Sarah Fidler, Jonathan Weber, Abdel Babiker, Rodney E Phillips, Angela R McLean, John Frater, SPARTAC trial investigators
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004914 (2015)
The existence of viral variants that escape from the selection pressures imposed by cytotoxic T-lymphocytes (CTLs) in HIV-1 infection is well documented, but it is unclear when they arise, with reported measures of the time to escape in individuals r
Externí odkaz:
https://doaj.org/article/fb909ad37e3f4906b5258b1013251d66
Autor:
James P Williams, Jacob Hurst, Wolfgang Stöhr, Nicola Robinson, Helen Brown, Martin Fisher, Sabine Kinloch, David Cooper, Mauro Schechter, Giuseppe Tambussi, Sarah Fidler, Mary Carrington, Abdel Babiker, Jonathan Weber, Kersten K Koelsch, Anthony D Kelleher, Rodney E Phillips, John Frater, on behalf of the SPARTAC trial investigators
Publikováno v:
eLife, Vol 3 (2014)
In HIV-1 infection, a population of latently infected cells facilitates viral persistence despite antiretroviral therapy (ART). With the aim of identifying individuals in whom ART might induce a period of viraemic control on stopping therapy, we hypo
Externí odkaz:
https://doaj.org/article/f1d39ff322244001a168899e1e5fad2c
Autor:
Wolfgang Stöhr, Sarah Fidler, Myra McClure, Jonathan Weber, David Cooper, Gita Ramjee, Pontiano Kaleebu, Giuseppe Tambussi, Mauro Schechter, Abdel Babiker, Rodney E Phillips, Kholoud Porter, John Frater
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78287 (2013)
OBJECTIVE:A minority of HIV-1 positive individuals treated with antiretroviral therapy (ART) in primary HIV-1 infection (PHI) maintain viral suppression on stopping. Whether this is related to ART duration has not been explored. DESIGN:And Methods: U
Externí odkaz:
https://doaj.org/article/59898a28b5d541c8adf63f832f2f7de2
Autor:
Lyle W Murray, Iman Satti, J Meyerowitz, Jacob Hurst, Matthew Jones, James E. Ussher, Rodney E. Phillips, Dominique Goedhals, John Frater, Cloete van Vuuren, Christian B. Willberg, Helen McShane
Publikováno v:
The Journal of Infectious Diseases. 217:1782-1792
Background Human immunodeficiency virus (HIV)-infected individuals have a higher risk of developing active tuberculosis (TB) than HIV-uninfected individuals, but the mechanisms underpinning this are unclear. We hypothesized that depletion of specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f163d7e4bf711aa749544bbb7ab4079
https://doi.org/10.1093/infdis/jiy052
https://doi.org/10.1093/infdis/jiy052
Autor:
Helen R Fryer, John Frater, Anna Duda, Mick G Roberts, SPARTAC Trial Investigators, Rodney E Phillips, Angela R McLean
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001196 (2010)
During infection with human immunodeficiency virus (HIV), immune pressure from cytotoxic T-lymphocytes (CTLs) selects for viral mutants that confer escape from CTL recognition. These escape variants can be transmitted between individuals where, depen
Externí odkaz:
https://doaj.org/article/98bae1164c074097b19e006d6645ab7c
Autor:
Angela R. McLean, Sarah Fidler, Kuan-Hsiang Gary Huang, Gil McVean, Philip J. R. Goulder, John Frater, Duncan S. Palmer, Cloete van Vuuren, Rodney E. Phillips, Dominique Goedhals, Roger L. Shapiro, Annette Oxenius, Isaac Turner
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications, 10 (1)
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications, 10 (1)
Differences among hosts, resulting from genetic variation in the immune system or heterogeneity in drug treatment, can impact within-host pathogen evolution. Genetic association studies can potentially identify such interactions. However, extensive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45882c947b54abf5d3b7293afc0719f4
Autor:
John, Frater, Fiona, Ewings, Jacob, Hurst, Helen, Brown, Nicola, Robinson, Sarah, Fidler, Abdel, Babiker, Jonathan, Weber, Kholoud, Porter, Rodney E, Phillips, C, Boocock
Publikováno v:
AIDS. 28:699-708
Objectives Immune factors determining clinical progression following HIV-1 infection remain unclear. The SPARTAC trial randomized 366 participants in primary HIV infection (PHI) to different short-course therapies. The aim of this study was to invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6089ccee49f56d10d8022006657c016
https://doi.org/10.1097/qad.0000000000000130
https://doi.org/10.1097/qad.0000000000000130
Autor:
Quentin A. Pankhurst, Helen C. Christian, James P. Williams, Andrew K. Sewell, Paul Southern, Anya Lissina, John Frater, Rodney E. Phillips
Publikováno v:
International Journal of Nanomedicine
Scopus-Elsevier
International Journal of Nanomedicine, Vol 2013, Iss default, Pp 2543-2554 (2013)
Scopus-Elsevier
International Journal of Nanomedicine, Vol 2013, Iss default, Pp 2543-2554 (2013)
James P Williams,1 Paul Southern,2 Anya Lissina,3 Helen C Christian,4 Andrew K Sewell,3 Rodney Phillips,1,5,6 Quentin Pankhurst,2 John Frater1,5,6 1Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford, UK; 2Davy-Faraday Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e202b3270c13591b1b4434c792e0a2c9
http://europepmc.org/articles/PMC3726440
http://europepmc.org/articles/PMC3726440
OBJECTIVE: To determine the cause of hyperglycemia in childhood diarrhea. METHODS: During an 8-month period, patients admitted to a diarrhea treatment center in Bangladesh had their blood glucose concentrations determined. Sixteen patients aged 2 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf189a554fd7d708d1c03125fd08a73
https://doi.org/10.1016/s0022-3476(97)70309-3
https://doi.org/10.1016/s0022-3476(97)70309-3