Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Rodney B. Luwor"'
Autor:
Bo Li PhD, Bo Gao Bachelor, Hong-Jian Zhu PhD, Rodney B. Luwor PhD, Jing Lu PhD, Lu Zhang Master, Bo Kong Master
Publikováno v:
Technology in Cancer Research & Treatment, Vol 23 (2024)
Introduction: The independent diagnostic value of inflammatory markers neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) and the diagnostic efficacy of NLR, derived neutrophil to lymphocyte ratio (dNLR), PLR, and lymphocyte-
Externí odkaz:
https://doaj.org/article/9877e10344934f10a427bfc93b7713bd
Reduced T and NK Cell Activity in Glioblastoma Patients Correlates with TIM-3 and BAT3 Dysregulation
Autor:
Farah Ahmady, Peter Curpen, Louis Perriman, Adilson Fonseca Teixeira, Siqi Wu, Hong-Jian Zhu, Arpita Poddar, Aparna Jayachandran, George Kannourakis, Rodney B. Luwor
Publikováno v:
Cells, Vol 13, Iss 21, p 1777 (2024)
Inhibitory receptors are critical for regulating immune cell function. In cancer, these receptors are often over-expressed on the cell surface of T and NK cells, leading to reduced anti-tumor activity. Here, through the analysis of 11 commonly studie
Externí odkaz:
https://doaj.org/article/d967a9d4ac04450a94dbe014016bc1eb
Autor:
Kieran W Benn, Patrick H Yuan, Harvey K Chong, Stanley S Stylii, Rodney B Luwor, Christopher R French
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0309438 (2024)
Gliomas are highly malignant brain tumours that remain refractory to treatment. Treatment is typically surgical intervention followed by concomitant temozolomide and radiotherapy; however patient prognosis remains poor. Voltage gated ion channels hav
Externí odkaz:
https://doaj.org/article/14a59a14d726402b96acfdb4158a01d4
Autor:
Sarah F. Stuart, Peter Curpen, Adele J. Gomes, Michelle C. Lan, Shuai Nie, Nicholas A. Williamson, George Kannourakis, Andrew P. Morokoff, Adrian A. Achuthan, Rodney B. Luwor
Publikováno v:
Brain Sciences, Vol 14, Iss 1, p 89 (2024)
Glioblastoma is highly proliferative and invasive. However, the regulatory cytokine networks that promote glioblastoma cell proliferation and invasion into other areas of the brain are not fully defined. In the present study, we define a critical rol
Externí odkaz:
https://doaj.org/article/67b463ca5fd74a849d24bbbf4752968b
Publikováno v:
Cells, Vol 13, Iss 2, p 192 (2024)
Background: Glioblastoma is characterised by extensive infiltration into the brain parenchyma, leading to inevitable tumor recurrence and therapeutic failure. Future treatments will need to target the specific biology of tumour recurrence, but our cu
Externí odkaz:
https://doaj.org/article/959993cf85e84517a64d3e2785b4e150
Autor:
Clarissa A. Whitehead, Hong P.T. Nguyen, Andrew P. Morokoff, Rodney B. Luwor, Lucia Paradiso, Andrew H. Kaye, Theo Mantamadiotis, Stanley S. Stylli
Publikováno v:
Translational Oncology, Vol 11, Iss 6, Pp 1406-1418 (2018)
The most common primary central nervous system tumor in adults is the glioblastoma multiforme (GBM). The highly invasive nature of GBM cells is a significant factor resulting in the inevitable tumor recurrence and poor patient prognosis. Tumor cells
Externí odkaz:
https://doaj.org/article/f12dddd8362b479aa8ff965b8d2781c6
Publikováno v:
Biophys J
Adherens junctions physically link two cells at their contact interface via extracellular binding between cadherin molecules and intracellular interactions between cadherins and the actin cytoskeleton. Cadherin and actomyosin cytoskeletal dynamics ar
Autor:
Sarah F. Stuart, Ayenachew Bezawork-Geleta, Zammam Areeb, Juliana Gomez, Vanessa Tsui, Ahmad Zulkifli, Lucia Paradiso, Jordan Jones, Hong P. T. Nguyen, Tracy L. Putoczki, Paul V. Licciardi, George Kannourakis, Andrew P. Morokoff, Adrian A. Achuthan, Rodney B. Luwor
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3356
Volume 24
Issue 4
Pages: 3356
Glioblastoma cells adapt to changes in glucose availability through metabolic plasticity allowing for cell survival and continued progression in low-glucose concentrations. However, the regulatory cytokine networks that govern the ability to survive
Autor:
Chenkai Ma, Hong P T Nguyen, Rodney B Luwor, Stanley S Stylli, Andrew Gogos, Lucia Paradiso, Andrew H Kaye, Andrew P Morokoff
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0189452 (2018)
Glioma is the most common malignant intracranial tumour. Recently, several publications have suggested that miRNAs can be used as potential diagnostic biomarkers of glioma. Here we performed a meta-analysis to identify the diagnostic accuracy of diff
Externí odkaz:
https://doaj.org/article/1d42c5e38fd649a5870464787d3b1aae