Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Roderick Clifton‐Bligh"'
Autor:
Ayanthi Wijewardene, Matti Gild, Lyndal Tacon, Venessa Tsang, Anthony J Gill, Anthony Robert Glover, Mark Sywak, Stan Sidhu, Bruce Robinson, Paul Roach, Geoffrey Schembri, Jeremy Hoang, Roderick Clifton-Bligh
Publikováno v:
Endocrine Connections, Vol 13, Iss 11, Pp 1-7 (2024)
Background: Noise, an unwanted variability in judgment, is ubiquitous in medicine, including in the prescription of radioactive iodine (RAI). Building upon our recently developed predictive risk model, we created an online clinical support tool to fa
Externí odkaz:
https://doaj.org/article/2f1faf20e1fd48eea8c1b375e35cdf9b
Autor:
Katherine Wu, Shejil Kumar, Ed Hsiao, Ian Kerridge, Min Ru Qiu, Rhonda Siddall, Roderick Clifton-Bligh, Anthony J Gill, Matti L Gild
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2024)
RET mutations are implicated in 60% of medullary thyroid cancer (MTC) cases. The RET-selective tyrosine kinase inhibitor selpercatinib is associated with unprecedented efficacy compared to previous multi-kinase treatments. Langerhans cell histiocytos
Externí odkaz:
https://doaj.org/article/aea4fae95cdc4b6b8b641b561091a060
Autor:
Peter Y.F. Zeng, Stephenie D. Prokopec, Stephen Y. Lai, Nicole Pinto, Michelle A. Chan-Seng-Yue, Roderick Clifton-Bligh, Michelle D. Williams, Christopher J. Howlett, Paul Plantinga, Matthew J. Cecchini, Alfred K. Lam, Iram Siddiqui, Jianxin Wang, Ren X. Sun, John D. Watson, Reju Korah, Tobias Carling, Nishant Agrawal, Nicole Cipriani, Douglas Ball, Barry Nelkin, Lisa M. Rooper, Justin A. Bishop, Cathie Garnis, Ken Berean, Norman G. Nicolson, Paul Weinberger, Ying C. Henderson, Christopher M. Lalansingh, Mao Tian, Takafumi N. Yamaguchi, Julie Livingstone, Adriana Salcedo, Krupal Patel, Frederick Vizeacoumar, Alessandro Datti, Liu Xi, Yuri E. Nikiforov, Robert Smallridge, John A. Copland, Laura A. Marlow, Martin D. Hyrcza, Leigh Delbridge, Stan Sidhu, Mark Sywak, Bruce Robinson, Kevin Fung, Farhad Ghasemi, Keith Kwan, S. Danielle MacNeil, Adrian Mendez, David A. Palma, Mohammed I. Khan, Mushfiq Shaikh, Kara M. Ruicci, Bret Wehrli, Eric Winquist, John Yoo, Joe S. Mymryk, James W. Rocco, David Wheeler, Steve Scherer, Thomas J. Giordano, John W. Barrett, William C. Faquin, Anthony J. Gill, Gary Clayman, Paul C. Boutros, Anthony C. Nichols
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113826- (2024)
Summary: Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are unknown. We sequenced tumor DNA from 329 regions of thyroid
Externí odkaz:
https://doaj.org/article/c5a6abf2e7ba48ce977235cab50cb266
Autor:
Sunita M. C. De Sousa, Angeline Shen, Christopher J. Yates, Roderick Clifton-Bligh, Stephen Santoreneos, James King, John Toubia, Giampaolo Trivellin, Andrea G. Lania, Constantine A. Stratakis, David J. Torpy, Hamish S. Scott
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionGermline loss-of-function variants in PAM, encoding peptidylglycine α-amidating monooxygenase (PAM), were recently discovered to be enriched in conditions of pathological pituitary hypersecretion, specifically: somatotrophinoma, corticot
Externí odkaz:
https://doaj.org/article/8744933f161647be97ed9c22bd62f41e
Autor:
Eleanor White, Bridget Abbott, Geoffrey Schembri, Anthony Glover, Roderick Clifton-Bligh, Matti L. Gild
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundActive surveillance (AS) is an alternative to surgery in select patients with very low risk papillary thyroid cancer (PTC). Many clinicians feel ill-equipped in selecting appropriate patients. We aimed to 1) Develop an evidence-based web de
Externí odkaz:
https://doaj.org/article/1aa80ab6cfbe4a559bc3657744422733
Publikováno v:
JBMR Plus, Vol 7, Iss 9, Pp n/a-n/a (2023)
ABSTRACT Hypervitaminosis D as a cause of hypercalcemia may be due to vitamin D intoxication, granulomatous diseases, or abnormalities of vitamin D metabolism. The CYP24A1 gene encodes for the 24‐hydroxylase enzyme, which is responsible for the cat
Externí odkaz:
https://doaj.org/article/6b379878253e48f9ac3247f97783ebba
Autor:
Magnus Zethoven, Luciano Martelotto, Andrew Pattison, Blake Bowen, Shiva Balachander, Aidan Flynn, Fernando J. Rossello, Annette Hogg, Julie A. Miller, Zdenek Frysak, Sean Grimmond, Lauren Fishbein, Arthur S. Tischler, Anthony J. Gill, Rodney J. Hicks, Patricia L. M. Dahia, Roderick Clifton-Bligh, Karel Pacak, Richard W. Tothill
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Pheochromocytomas and paragangliomas (PCPG) are rare neuroendocrine tumours. Here, the authors use single-nuclei and bulk-tissue RNA-seq to characterise PCPG tumours and their microenvironments and reveal molecular subtypes as well as expression patt
Externí odkaz:
https://doaj.org/article/acb443b3a4054e5aa516e6bf96075901
Autor:
Dominic Hauck, Liza Nery, Rachel O'Connell, Roderick Clifton-Bligh, Amanda Mather, Christian M. Girgis
Publikováno v:
Bone Reports, Vol 16, Iss , Pp 101178- (2022)
Chronic Kidney Disease Stage 5 (CKD-5) imparts a 4-fold increase in minimal trauma fracture with a substantial increase in mortality following hip fracture. Bone disease in CKD is complex, characterised by abnormal levels of PTH, calcium, phosphate,
Externí odkaz:
https://doaj.org/article/dc7913c28e794a43aabc0106204970a5
Autor:
Ashlesha Akella, Avinash Kumar Singh, Daniel Leong, Sara Lal, Phillip Newton, Roderick Clifton-Bligh, Craig Steven Mclachlan, Sylvia Maria Gustin, Shamona Maharaj, Ty Lees, Zehong Cao, Chin-Teng Lin
Publikováno v:
IEEE Journal of Translational Engineering in Health and Medicine, Vol 9, Pp 1-9 (2021)
Objective: Mental stress is a major problem in our society and has become an area of interest for many psychiatric researchers. One primary research focus area is the identification of bio-markers that not only identify stress but also predict the co
Externí odkaz:
https://doaj.org/article/6e134d33489b46a28b44589b4385daef
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2020)
Lymphocytic hypophysitis is a rare neuroendocrine disease characterised by an autoimmune inflammatory disorder of the pituitary gland. We report a 50-year-old woman who presented with headaches and bilateral sixth cranial nerve palsies. MRI of the pi
Externí odkaz:
https://doaj.org/article/b1d5a11424c34ed9a8625d0dfc00767b