Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Roderich Roemhild"'
Autor:
Aditi Batra, Roderich Roemhild, Emilie Rousseau, Sören Franzenburg, Stefan Niemann, Hinrich Schulenburg
Publikováno v:
eLife, Vol 10 (2021)
Evolutionary adaptation is a major source of antibiotic resistance in bacterial pathogens. Evolution-informed therapy aims to constrain resistance by accounting for bacterial evolvability. Sequential treatments with antibiotics that target different
Externí odkaz:
https://doaj.org/article/663307e161784e63bba23b20f9e20b9c
Autor:
Roderich Roemhild, Dan I Andersson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009172 (2021)
Externí odkaz:
https://doaj.org/article/0bd94d9b8d0f403d91e4c9f251b2fdb1
Publikováno v:
PLoS Biology, Vol 18, Iss 9, p e3000856 (2020)
Antibiotic combination therapies are important for the efficient treatment of many types of infections, including those caused by antibiotic-resistant pathogens. Combination treatment strategies are typically used under the assumption that synergies
Externí odkaz:
https://doaj.org/article/b14d784b405d41fc8380ad34ff9a7191
Publikováno v:
PLoS Biology, Vol 18, Iss 1, p e3000612 (2020)
Antibiotic resistance increasingly limits the success of antibiotic treatments, and physicians require new ways to achieve efficient treatment despite resistance. Resistance mechanisms against a specific antibiotic class frequently confer increased s
Externí odkaz:
https://doaj.org/article/e865493985314f5fa2eea8dc6e51481c
Publikováno v:
Nature reviews. Microbiology. 20(8)
Several promising strategies based on combining or cycling different antibiotics have been proposed to increase efficacy and counteract resistance evolution, but we still lack a deep understanding of the physiological responses and genetic mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c78d33eb1c9443b7e4b30ae473e643
https://pubmed.ncbi.nlm.nih.gov/35241807
https://pubmed.ncbi.nlm.nih.gov/35241807
Autor:
Hinrich Schulenburg, Roderich Roemhild
Publikováno v:
Evolution, Medicine, and Public Health. 2019:37-45
The spread of antibiotic resistance is a global challenge that is fueled by evolution and ecological processes. Therefore, the design of new sustainable therapy should take account of these underlying processes-as proposed within the field of evoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6228dc3c2b64ffa08eb54104e07b1057
https://doi.org/10.1093/emph/eoz008
https://doi.org/10.1093/emph/eoz008
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Evolution is at the core of the impending antibiotic crisis. Sustainable therapy must thus account for the adaptive potential of pathogens. One option is to exploit evolutionary trade-offs, like collateral sensitivity, where evolved resistance to one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4dc9bf11ff5a8d327ea65d8c888bead
https://hdl.handle.net/21.11116/0000-0005-17EE-621.11116/0000-0005-17F0-2
https://hdl.handle.net/21.11116/0000-0005-17EE-621.11116/0000-0005-17F0-2
Evolution is at the core of the impending antibiotic crisis. Sustainable therapy must thus account for the adaptive potential of pathogens. One option is to exploit evolutionary trade-offs, like collateral sensitivity, where evolved resistance to one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2b86f4ba8e4d3d2ad4fd016afd5358
Publikováno v:
Evolution, Medicine, and Public Health
The spread of antibiotic resistance is a global challenge that is fueled by evolution and ecological processes. Therefore, the design of new sustainable therapy should take account of these underlying processes—as proposed within the field of evolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4fd59740e019f05f574ebda06d30cd1
https://pubmed.ncbi.nlm.nih.gov/30906555
https://pubmed.ncbi.nlm.nih.gov/30906555