Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Roderic Guigo"'
Autor:
Emeline Favreau, Alessandro Cini, Daisy Taylor, Francisco Câmara Ferreira, Michael A. Bentley, Federico Cappa, Rita Cervo, Eyal Privman, Jadesada Schneider, Denis Thiéry, Rahia Mashoodh, Christopher D. R. Wyatt, Robert L. Brown, Alexandrina Bodrug-Schepers, Nancy Stralis-Pavese, Juliane C. Dohm, Daniel Mead, Heinz Himmelbauer, Roderic Guigo, Seirian Sumner
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Hornets are the largest of the social wasps, and are important regulators of insect populations in their native ranges. Hornets are also very successful as invasive species, with often devastating economic, ecological and societal effects. U
Externí odkaz:
https://doaj.org/article/ab4084123ddc413e83e3c3d008bbeae0
Autor:
Blanca Rodríguez-Fernández, Juan Domingo Gispert, Roderic Guigo, Arcadi Navarro, Natalia Vilor-Tejedor, Marta Crous-Bou
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4251-4256 (2022)
Telomere length (TL) is a biomarker of biological aging. Shorter telomeres have been associated with mortality and increased rates of age-related diseases. However, observational studies are unable to conclude whether TL is causally associated with t
Externí odkaz:
https://doaj.org/article/b8667d4c18d946fb939813a9d2ea83e1
Autor:
Iman Sadeghi, Juan D. Gispert, Emilio Palumbo, Manuel Muñoz-Aguirre, Valentin Wucher, Valeria D'Argenio, Gabriel Santpere, Arcadi Navarro, Roderic Guigo, Natàlia Vilor-Tejedor
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4549-4561 (2022)
Neurodegenerative and neuropsychiatric disorders (ND-NPs) are multifactorial, polygenic and complex behavioral phenotypes caused by brain abnormalities. Large-scale collaborative efforts have tried to identify the genetic architecture of these condit
Externí odkaz:
https://doaj.org/article/aedc58d2e187429084e7189989cf72bb
Autor:
Natalia Vilor-Tejedor, Iacopo Ciampa, Grégory Operto, Carles Falcón, Marc Suárez-Calvet, Marta Crous-Bou, Mahnaz Shekari, Eider M. Arenaza-Urquijo, Marta Milà-Alomà, Oriol Grau-Rivera, Carolina Minguillon, Gwendlyn Kollmorgen, Henrik Zetterberg, Kaj Blennow, Roderic Guigo, José Luis Molinuevo, Juan Domingo Gispert, for the ALFA study
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Background Perivascular spaces (PVS) have an important role in the elimination of metabolic waste from the brain. It has been hypothesized that the enlargement of PVS (ePVS) could be affected by pathophysiological mechanisms involved in Alzh
Externí odkaz:
https://doaj.org/article/3363e3bb6bce440f889f942c7aff53db
Autor:
Maroun Bou Sleiman, Michael Vincent Frochaux, Tommaso Andreani, Dani Osman, Roderic Guigo, Bart Deplancke
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-19 (2020)
Abstract Background RNA splicing is a key post-transcriptional mechanism that generates protein diversity and contributes to the fine-tuning of gene expression, which may facilitate adaptation to environmental challenges. Here, we employ a systems ap
Externí odkaz:
https://doaj.org/article/3d9ca418408842eca65439d8d29521d4
Autor:
Roderic Guigo, Michiel de Hoon
Publikováno v:
F1000Research, Vol 7 (2018)
At the beginning of this century, the Human Genome Project produced the first drafts of the human genome sequence. Following this, large-scale functional genomics studies were initiated to understand the molecular basis underlying the translation of
Externí odkaz:
https://doaj.org/article/9d91f357689843b9a09ee8be84da01d0
Autor:
Carlos Pulido-Quetglas, Estel Aparicio-Prat, Carme Arnan, Taisia Polidori, Toni Hermoso, Emilio Palumbo, Julia Ponomarenko, Roderic Guigo, Rory Johnson
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 3, p e1005341 (2017)
CRISPR-Cas9 technology can be used to engineer precise genomic deletions with pairs of single guide RNAs (sgRNAs). This approach has been widely adopted for diverse applications, from disease modelling of individual loci, to parallelized loss-of-func
Externí odkaz:
https://doaj.org/article/625ef4ed10824d3d8ced8510c0d3e706
Autor:
Marco Mariotti, Perry G Ridge, Yan Zhang, Alexei V Lobanov, Thomas H Pringle, Roderic Guigo, Dolph L Hatfield, Vadim N Gladyshev
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33066 (2012)
Selenium is an essential trace element in mammals due to its presence in proteins in the form of selenocysteine (Sec). Human genome codes for 25 Sec-containing protein genes, and mouse and rat genomes for 24.We characterized the selenoproteomes of 44
Externí odkaz:
https://doaj.org/article/5e4a9ae10fbd418b943eb7f0295a4369
Autor:
Sílvia Carbonell-Sala, Tamara Perteghella, Julien Lagarde, Hiromi Nishiyori, Emilio Palumbo, Carme Arnan, Hazuki Takahashi, Piero Carninci, Barbara Uszczynska-Ratajczak, Roderic Guigó
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Long-read RNA sequencing is essential to produce accurate and exhaustive annotation of eukaryotic genomes. Despite advancements in throughput and accuracy, achieving reliable end-to-end identification of RNA transcripts remains a challenge f
Externí odkaz:
https://doaj.org/article/6f0dff57dab14db685b630a7d127b446
Autor:
Adam Frankish, Sílvia Carbonell-Sala, Mark Diekhans, Irwin Jungreis, Jane E Loveland, Jonathan M Mudge, Cristina Sisu, James C Wright, Carme Arnan, If Barnes, Abhimanyu Banerjee, Ruth Bennett, Andrew Berry, Alexandra Bignell, Carles Boix, Ferriol Calvet, Daniel Cerdán-Vélez, Fiona Cunningham, Claire Davidson, Sarah Donaldson, Cagatay Dursun, Reham Fatima, Stefano Giorgetti, Carlos Garcıa Giron, Jose Manuel Gonzalez, Matthew Hardy, Peter W Harrison, Thibaut Hourlier, Zoe Hollis, Toby Hunt, Benjamin James, Yunzhe Jiang, Rory Johnson, Mike Kay, Julien Lagarde, Fergal J Martin, Laura Martínez Gómez, Surag Nair, Pengyu Ni, Fernando Pozo, Vivek Ramalingam, Magali Ruffier, Bianca M Schmitt, Jacob M Schreiber, Emily Steed, Marie-Marthe Suner, Dulika Sumathipala, Irina Sycheva, Barbara Uszczynska-Ratajczak, Elizabeth Wass, Yucheng T Yang, Andrew Yates, Zahoor Zafrulla, Jyoti S Choudhary, Mark Gerstein, Roderic Guigo, Tim J P Hubbard, Manolis Kellis, Anshul Kundaje, Benedict Paten, Michael L Tress, Paul Flicek
Publikováno v:
Frankish, Adam; Carbonell-Sala, Sílvia; Diekhans, Mark; Jungreis, Irwin; Loveland, Jane E; Mudge, Jonathan M; Sisu, Cristina; Wright, James C; Arnan, Carme; Barnes, If; Banerjee, Abhimanyu; Bennett, Ruth; Berry, Andrew; Bignell, Alexandra; Boix, Carles; Calvet, Ferriol; Cerdán-Vélez, Daniel; Cunningham, Fiona; Davidson, Claire; Donaldson, Sarah; ... (2023). GENCODE: reference annotation for the human and mouse genomes in 2023. Nucleic acids research, 51(D1), D942-D949. Oxford University Press 10.1093/nar/gkac1071
Data availability: No new data were generated or analysed in support of this research. Copyright © The Author(s) 2022. GENCODE produces high quality gene and transcript annotation for the human and mouse genomes. All GENCODE annotation is supported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10247881d8c4fbceb604577e5be9e5ad