Zobrazeno 1 - 10
of 3 680
pro vyhledávání: '"Rodent model"'
Publikováno v:
Beni-Suef University Journal of Basic and Applied Sciences, Vol 13, Iss 1, Pp 1-10 (2024)
Abstract Background Cytokines, known for their pro- and anti-inflammatory roles, are also key regulators of sleep–wake cycles. Classical pro-inflammatory cytokines, such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-α), are associat
Externí odkaz:
https://doaj.org/article/0492925591314506be0393f404fb00a0
Publikováno v:
Redox Biology, Vol 77, Iss , Pp 103402- (2024)
Oxidative stress is a crucial concept in redox biology, and significant progress has been made in recent years. Excessive levels of reactive oxygen species (ROS) can lead to oxidative damage, heightening vulnerability to various diseases. By contrast
Externí odkaz:
https://doaj.org/article/c331cf4fe9e54bcf8a41064e1d5bd4e3
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract The glymphatic system plays an important role in the transportation of cerebrospinal fluid (CSF) and the clearance of metabolite waste in brain. However, current imaging modalities for studying the glymphatic system are limited. Herein, we a
Externí odkaz:
https://doaj.org/article/43989d34056a4c65b38f666eb3b4349b
Autor:
Megan E. Rosa‐Caldwell, Lauren Breithaupt, Ursula B. Kaiser, Eliza Garland, Sheridyn Pinkham, Madisyn Hancock, Sophie L. Jalkut, Seward B. Rutkove
Publikováno v:
Physiological Reports, Vol 12, Iss 12, Pp n/a-n/a (2024)
Abstract Current rodent models of anorexia nervosa (AN) often have accelerated weight loss that often do not allow for investigation of physiological ramifications of prolonged low weight status characteristic of AN. The purpose of this project was t
Externí odkaz:
https://doaj.org/article/f872ac7fe8124790a1838f1bc2019526
Autor:
Sofia Spataro, Bohumil Maco, Stéphane Escrig, Louise Jensen, Lubos Polerecky, Graham Knott, Anders Meibom, Bernard L. Schneider
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract In Parkinson’s disease, pathogenic factors such as the intraneuronal accumulation of the protein α-synuclein affect key metabolic processes. New approaches are required to understand how metabolic dysregulations cause degeneration of vuln
Externí odkaz:
https://doaj.org/article/4df05915fb974e5a96d48ef8028a1f10
Publikováno v:
Microorganisms, Vol 12, Iss 8, p 1537 (2024)
Peri-implantitis (PI) is a current concern whose understanding and resolution are ongoing. We aimed to evaluate in vivo a new treatment with antibacterial properties, based on bacterial lysates obtained from the strains of Aggregatibacter actinomycet
Externí odkaz:
https://doaj.org/article/df7135e6cef74c468d956a3041774f9b
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Arteriovenous fistulas (AVFs) have long been used as dialysis access in patients with end-stage renal disease; however, their maturation and long-term patency still fall short of clinical needs. Rodent models are irreplaceable to facilitate the study
Externí odkaz:
https://doaj.org/article/f44228f743b143698e2fb958a86e0a3c
Autor:
Sebastian Billig, Marc Hein, Celine Kirchner, David Schumacher, Moriz Aljoscha Habigt, Mare Mechelinck, Dieter Fuchs, Uwe Klinge, Alexander Theißen, Christian Beckers, Christian Bleilevens, Rafael Kramann, Moritz Uhlig
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 876 (2024)
Background: Previous studies have shown cardiac abnormalities in acute liver injury, suggesting a potential role in the associated high mortality. Methods: We designed an experimental study exploring the short-term effects of acute cholestasis-induce
Externí odkaz:
https://doaj.org/article/fca834b394cb4b9f8df1b39aafc30183
Publikováno v:
Tzu-Chi Medical Journal, Vol 35, Iss 1, Pp 18-23 (2023)
Cerebrospinal fluid (CSF) and its drainage are crucial in clearing metabolic waste and maintaining the microenvironment of the central nervous system for proper functioning. Normal-pressure hydrocephalus (NPH) is a serious neurological disorder of th
Externí odkaz:
https://doaj.org/article/98b499b02a44447c8e94db5bfa175763
Autor:
Jennifer D. Sokolowski, Sauson Soldozy, Khadijeh A. Sharifi, Pedro Norat, Kathryn N. Kearns, Lei Liu, Ashley M. Williams, Kaan Yağmurlu, Panagiotis Mastorakos, G. Wilson Miller, M. Yashar S. Kalani, Min S. Park, Ryan T. Kellogg, Petr Tvrdik
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Stroke remains a major burden on patients, families, and healthcare professionals, despite major advances in prevention, acute treatment, and rehabilitation. Preclinical basic research can help to better define mechanisms contributing to stroke patho
Externí odkaz:
https://doaj.org/article/f27a5a27e1ab4c8cad22c1e02a0929a5