3,5-disubstituted pyridines with potent activity against drug-resistant Mycobacterium tuberculosis clinical isolates.

Autor: Sangu KG; Department of Natural Products & Medicinal Chemistry, CSIR - Indian Institute of Chemical Technology, Tarnaka, Hyderabad, 500 007, India.; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201 002, India., Azger Dusthackeer VN; Department of Bacteriology, National Institute for Research in Tuberculosis, Chennai, 600 031, India., Singh VK; Department of Natural Products & Medicinal Chemistry, CSIR - Indian Institute of Chemical Technology, Tarnaka, Hyderabad, 500 007, India., Maykalwar S; Department of Natural Products & Medicinal Chemistry, CSIR - Indian Institute of Chemical Technology, Tarnaka, Hyderabad, 500 007, India.; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201 002, India., Krishna EV; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201 002, India.; Department of Applied Biology, CSIR - Indian Institute of Chemical Technology, Tarnaka, Hyderabad, 500 007, India., Angayarkanni B; Department of Bacteriology, National Institute for Research in Tuberculosis, Chennai, 600 031, India., Maitra R; Department of Molecular Microbiology & Immunology, CSIR - Central Drug Research Institute, Sitapur Road, Janakipuram Extension, Lucknow, Uttar Pradesh, 226 031, India., Chopra S; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201 002, India.; Department of Molecular Microbiology & Immunology, CSIR - Central Drug Research Institute, Sitapur Road, Janakipuram Extension, Lucknow, Uttar Pradesh, 226 031, India., Misra S; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201 002, India.; Department of Applied Biology, CSIR - Indian Institute of Chemical Technology, Tarnaka, Hyderabad, 500 007, India., Rode HB; Department of Natural Products & Medicinal Chemistry, CSIR - Indian Institute of Chemical Technology, Tarnaka, Hyderabad, 500 007, India.; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, 201 002, India.

Publikováno v: Future medicinal chemistry [Future Med Chem] 2024 Oct 03, pp. 1-19. Date of Electronic Publication: 2024 Oct 03.

Iron mediated reductive cyclization/oxidation for the generation of chemically diverse scaffolds: An approach in drug discovery.

Autor: Karale UB; Department of Natural Products and Medicinal Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201 002, India., Shinde A; Department of Natural Products and Medicinal Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India., Gaikwad VR; Department of Natural Products and Medicinal Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India., Kalari S; Department of Natural Products and Medicinal Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201 002, India., Gourishetti K; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201 002, India; Department of Applied Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India., Radhakrishnan M; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201 002, India; Department of Applied Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India., Poornachandra Y; Department of Applied Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India., Amanchy R; Department of Applied Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India., Chakravarty S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201 002, India; Department of Applied Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India., Andugulapati SB; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201 002, India; Department of Applied Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India., Rode HB; Department of Natural Products and Medicinal Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201 002, India. Electronic address: haridas.rode@iict.res.in.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2023 Oct; Vol. 139, pp. 106698. Date of Electronic Publication: 2023 Jun 23.

Synthesis and evaluation of novel almazole D analogs as anticancer agents.

Autor: Oluyori AP; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India.; Department of Physical Sciences, Landmark University, Omu Aran, Kwara State, Nigeria.; Landmark University Sustainable Development Goal 3, Good Health and Well-Being, Nigeria, Omu Aran, Kwara., Harini T; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, India., Sangu KG; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, India., Krishna EV; Department of Applied Biology, Microbiology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India., Jadav SS; Department of Applied Biology, Microbiology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India., Misra S; Department of Applied Biology, Microbiology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India., Rode HB; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, India.

Publikováno v: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2022 Nov; Vol. 355 (11), pp. e2200102. Date of Electronic Publication: 2022 Aug 01.

Selectfluor-Mediated Synthesis of β-Acyl Allyl Sulfones/β-Acyl Allyl Benzotriazoles from Ketones/Acetylenes, Aryl Sulfinates/Benzotriazole, and DMSO as a Dual-Carbon Synthon.

Autor: Kalari S; Department of Organic Synthesis and Process Chemistry, CSIR─Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201002, India., Karale UB; Department of Organic Synthesis and Process Chemistry, CSIR─Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201002, India., Rode HB; Department of Organic Synthesis and Process Chemistry, CSIR─Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201002, India.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2022 Mar 04; Vol. 87 (5), pp. 2435-2445. Date of Electronic Publication: 2022 Jan 13.

Methylene-Tethered Arylsulfonation and Benzotriazolation of Aryl/Heteroaryl C-H Bonds with DMSO as a One-Carbon Surrogate.

Autor: Kalari S; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201 002, India., Shinde AU; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India., Rode HB; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201 002, India.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2021 Dec 17; Vol. 86 (24), pp. 17684-17695. Date of Electronic Publication: 2021 Dec 01.