Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Rod Rassekh"'
Autor:
Rebecca Ronsley, Celine D. Hounjet, Sylvia Cheng, Shahrad Rod Rassekh, Walter J. Duncan, Christopher Dunham, Jane Gardiner, Arvindera Ghag, Jeffrey P. Ludemann, David Wensley, Wingfield Rehmus, Michael A. Sargent, Juliette Hukin
Publikováno v:
Cancer Medicine, Vol 10, Iss 11, Pp 3556-3564 (2021)
Abstract Purpose To describe a series of children with extensive PNF or treatment refractory PLGG treated on a compassionate basis with trametinib. Methods We report on six patients with NF‐1 treated with trametinib on a compassionate basis at Brit
Externí odkaz:
https://doaj.org/article/778056853ba44d84ae5379fbb35ac161
Autor:
Rebecca Ronsley, Shahrad Rod Rassekh, Adam Fleming, Brianna Empringham, William Jennings, Carol Portwine, Sarah Burrow, Shayna Zelcer, Donna L. Johnston, Lehana Thabane, M. Constantine Samaan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract While children with brain tumors are surviving at record rates, survivors are at risk of cardiovascular disease and type 2 diabetes mellitus; these conditions may be driven by excess body fat. Adiponectin in an adipokine that is inversely as
Externí odkaz:
https://doaj.org/article/29199f71613041b7a3dd85f406e5a55e
A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol
Autor:
Anshika Jain, Ryan Huang, Jasmine Lee, Natasha Jawa, Yong Jin Lim, Mike Guron, Sharon Abish, Paul C. Boutros, Michael Brudno, Bruce Carleton, Geoffrey D. E. Cuvelier, Lakshman Gunaratnam, Cheryl Ho, Khosrow Adeli, Sara Kuruvilla, Giles Lajoie, Geoffrey Liu, Paul C. Nathan, Shahrad Rod Rassekh, Michael Rieder, Sushrut S. Waikar, Stephen A. Welch, Matthew A. Weir, Eric Winquist, David S. Wishart, Alexandra P. Zorzi, Tom Blydt-Hansen, Michael Zappitelli, Bradley Urquhart
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 8 (2021)
Background: Cisplatin, a chemotherapy used to treat solid tumors, causes acute kidney injury (AKI), a known risk factor for chronic kidney disease and mortality. AKI diagnosis relies on biomarkers which are only measurable after kidney damage has occ
Externí odkaz:
https://doaj.org/article/15b7986c609a42cb8982f5a706c42a37
Publikováno v:
Therapeutic Drug Monitoring. 45:337-344
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Clinical significance in a randomized controlled trial (RCT) can be determined using the minimal clinically important difference (MCID), which should inform the delta value used to determine sample size. The primary objective was
Externí odkaz:
https://doaj.org/article/8fddcfa264424f1b84f0cb3784803a51
Autor:
Kuan-Wen Wang, Russell J. de Souza, Adam Fleming, Donna L. Johnston, Shayna M. Zelcer, Shahrad Rod Rassekh, Sarah Burrow, Lehana Thabane, M. Constantine Samaan
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Children with brain tumors (CBT) are at higher risk of cardiovascular disease and type 2 diabetes compared to the general population, in which birth weight is a risk factor for these diseases. However, this is not known in CBT. The primary a
Externí odkaz:
https://doaj.org/article/fe91679aaf0d470f9e55db4385badbf6
Publikováno v:
Pediatric Nephrology. 38:1667-1685
Autor:
Richard J Huntsman, Jesse Elliott, Evan Lewis, Charlotte Moore-Hepburn, Jane Alcorn, Holly Mansell, Juan P Appendino, Richard E Bélanger, Scott Corley, Bruce Crooks, Anne Marie M Denny, Yaron Finkelstein, Allen Finley, Ryan Fung, Andrea Gilpin, Catherine Litalien, Julia Jacobs, Timothy F Oberlander, Ashley Palm, Jacob Palm, Monika Polewicz, Declan Quinn, S Rod Rassekh, Alexander Repetski, Michael J Rieder, Amy Robson-McKay, Blair Seifert, Alan Shackelford, Hal Siden, Michael Szafron, Geert ‘t Jong, Régis Vaillancourt, Lauren E Kelly
Publikováno v:
Paediatrics & Child Health.
Medical cannabis (MC) may offer therapeutic benefits for children with complex neurological conditions and chronic diseases. In Canada, parents, and caregivers frequently report encountering barriers when accessing MC for their children. These includ
Autor:
Sandra E. Dunn, Christopher Dunham, Sheila K. Singh, Paul Northcott, Stephen Yip, Rod Rassekh, Juliette Hukin, Ash Singhal, Michael D. Taylor, Eric Bouffet, Vijay Ramaswamy, Cynthia Hawkins, Aru Narendran, Katrina O'Halloran, Chitra Venugopal, Abbas Fotovati, Rachel Berns, Mary Rose Pambid, Branavan Manoranjan, Colleen Foster, Cathy Lee, Joanna Triscott
Medulloblastoma is the most common malignant brain tumor in children. This disease is heterogeneous and is composed of four subtypes of medulloblastoma [WNT, Sonic Hedgehog (SHH), Group 3, and Group 4]. An immediate goal is to identify novel molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2676c0f11180d32a7b8ade9835657025
https://doi.org/10.1158/0008-5472.c.6505601
https://doi.org/10.1158/0008-5472.c.6505601
Autor:
Sandra E. Dunn, Christopher Dunham, Sheila K. Singh, Paul Northcott, Stephen Yip, Rod Rassekh, Juliette Hukin, Ash Singhal, Michael D. Taylor, Eric Bouffet, Vijay Ramaswamy, Cynthia Hawkins, Aru Narendran, Katrina O'Halloran, Chitra Venugopal, Abbas Fotovati, Rachel Berns, Mary Rose Pambid, Branavan Manoranjan, Colleen Foster, Cathy Lee, Joanna Triscott
PDF file - 80K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1105923776f2fa6159acbf1c2f1d4367
https://doi.org/10.1158/0008-5472.22400492.v1
https://doi.org/10.1158/0008-5472.22400492.v1