Výsledky vyhledávání - "Rod K. Ferrier"

Gastrokine 1 is abundantly and specifically expressed in superficial gastric epithelium, down-regulated in gastric carcinoma, and shows high evolutionary conservation

Autor: Steven Bryce, Sharon Burns, Fiona McGregor, W. Nicol Keith, Ian Downie, Karin A. Oien, Rod K Ferrier, Sharlene Butler

Publikováno v: The Journal of Pathology. 203:789-797

Through previous large-scale gene expression profiling we identified a transcript that was abundant in normal stomach and down-regulated in gastric cancer. Genes expressed at similar levels included gastrin, MUC5 and pS2, which are important in gastr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648d3adb68f7e127213b94fe02e0f342
https://doi.org/10.1002/path.1583

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In healthy volunteers, immunohistochemistry supports squamous to columnar metaplasia as mechanism of expansion of cardia, aggravated by central obesity

Autor: Scott L. Hanvey, Clare Orange, Elaine V. Robertson, Mohammad H. Derakhshan, Angela A. Wirz, James J. Going, Yeong Yeh Lee, Rod K. Ferrier, Stuart Ballantyne, Kenneth E.L. McColl, Tim Harvey

Publikováno v: Gut. 64(11)

Introduction Recently, we showed that the length of cardiac mucosa in healthy volunteers correlated with age and obesity. We have now examined the immunohistological characteristics of this expanded cardia to determine whether it may be due to column

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba529165b392d0146c667c3543b2f3f
https://pubmed.ncbi.nlm.nih.gov/25809636

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Hepatocyte proliferation and serum hepatocyte growth factor levels in patients with alcoholic hepatitis

Autor: Ian C. McKay, Kenneth J. Hillan, R.N.M. MacSween, Rod K. Ferrier, George L. A. Bird, Gregory L. Bennett, Martin C. Logan

Publikováno v: Journal of Hepatology. 24:385-390

Hepatocyte growth factor is thought to be important in stimulating growth of the liver following injury. In this study we have measured serum levels of hepatocyte growth factor together with hepatocyte proliferation in liver biopsies, by detection of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7929b9fb4fd007da2982af26f4f510da
https://doi.org/10.1016/s0168-8278(96)80157-7

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The Effects of ZENECA ZD8731, an Angiotensin II Antagonist, on Renin Expression by Juxtaglomerular Cells in the Rat: Comparison of Protein and mRNA Expression as Detected by Immunohistochemistry and In Situ Hybridization

Autor: Kenneth J. Hillan, Susan E. Doughty, Rod K. Ferrier, David G. Jackson

Publikováno v: Toxicologic Pathology. 23:256-261

Changes in the mRNA and protein expression of renin-secreting cells in the juxtaglomerular apparatus (JGA) were examined in the rat following administration of ZENECA ZD8731, an angiotensin II receptor antagonist. Doses of 0 or 90 mg/kg were administ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d77bbbd7cfc2f9614e55bb24c38590
https://doi.org/10.1177/019262339502300303

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PTH-192 Gastric adenocarcinoma of diffuse type develops on a healthy-looking mucosal background, unlike intestinal type gastric adenocarcinoma

Autor: Mohammad H. Derakhshan, Rod K. Ferrier, James J. Going, T Iwata, Clare Orange, X Zhang

Publikováno v: Gut. 64:A493.2-A494

Introduction Intestinal type gastric adenocarcinoma develops in an inflammatory and atrophic background with profound loss of secretory cells. Little is known about background gastric mucosa in diffuse type adenocarcinoma. Method Total gastrectomy sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80af6878bae1c5360e7aaa4a233be879
https://doi.org/10.1136/gutjnl-2015-309861.1080

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DEMONSTRATION OF RENIN GENE EXPRESSION IN NEPHROBLASTOMA BYIN SITU HYBRIDIZATION

Autor: George B. M. Lindop, Rod K. Ferrier, Alan G. Howatson, Kathryn J. McKENZIE

Publikováno v: The Journal of Pathology. 180:71-73

Most patients with nephroblastoma have high levels of plasma renin and some are hypertensive. Blood pressure falls after removal of the affected kidney, suggesting that nephroblastoma is associated with renin production either by the tumour or by the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d521f793900918b2dbd535365a455584
https://doi.org/10.1002/(sici)1096-9896(199609)180:1<71::aid-path634>3.0.co

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Sa1867 Evidence of Two Aetiologies of Gastroesophageal Junctional Cancers Based on Gastric Parietal Cell Density

Autor: James J. Going, Clare Orange, Tim Harvey, Matthew Forshaw, Rod K. Ferrier, Elaine V. Robertson, Kenneth E.L. McColl, Mohammad H. Derakhshan

Publikováno v: Gastroenterology. 146:S-316

Introduction Serum pepsinogen I:II ratio, a surrogate marker of atrophic gastritis, suggests that some adenocarcinomas at the gastroesophageal junction (GOJ) develop on a background of atrophic gastritis, similar to non-cardia gastric cancer, while o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::984d0881bdfdc843f2140e3847af3b59
https://doi.org/10.1016/s0016-5085(14)61136-7

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Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease

Autor: Rod K. Ferrier, Sherman Fong, H H Chiu, Kenneth J. Hillan, Amar P. Dhillon, G. L. A. Bird, Mark Renz, Linda D. Ferrell, Kelly E. Hagler, Roderick N. M. MacSween, Anne M. Ryan

Publikováno v: Liver. 19(6)

Aims/Background: The integrin alpha 4 beta 7 and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) are involved in normal recirculation of lymphocytes between the blood and the tissues of the gastrointestinal tract. In this study we have examined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fdea5b2a8185f428043feab594d46b
https://pubmed.ncbi.nlm.nih.gov/10661685

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Characterization of the expression of DMPK and SIX5 in the human eye and implications for pathogenesis in myotonic dystrophy

Autor: Rod K. Ferrier, Brian J. Clark, Keith J. Johnson, Catherine L Winchester, Adriana Sermoni

Publikováno v: Human molecular genetics. 8(3)

The pathogenic mechanisms underlying myotonic dystrophy (DM), which results from a (CTG) n repeat expansion mutation in the 3'-untranslated region (3'-UTR) of the myotonic dystrophy protein kinase gene ( DMPK ), remain obscure. The multisystemic natu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9bbaf4dc8c8f8edd731395e769a0727
https://pubmed.ncbi.nlm.nih.gov/9949207

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