Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rod Bronson"'
Autor:
James D. Griffin, Nathanael S. Gray, Ellen Weisberg, Richard Stone, Zheng Zhao, Wooyoung Hur, Robert J. Smith, Erik Nelson, Amanda L. Christie, John F. Daley, Constantine S. Mitsiades, Ilene Galinsky, Rod Bronson, Qingsong Liu, Andrew L. Kung, Martin Sattler, Takaomi Sanda
Publikováno v:
Leukemia. 26:2233-2244
Acute myeloid leukemia (AML) progenitors are frequently characterized by activating mutations in the receptor tyrosine kinase Fms-like tyrosine kinase-3 (FLT3). Protein tyrosine kinases are integral components of signaling cascades that have a role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33f1c91be9bb1d16f66a370008238260
https://doi.org/10.1038/leu.2012.96
https://doi.org/10.1038/leu.2012.96
Autor:
Amanda L. Christie, Rod Bronson, Ellen Weisberg, Irene M. Ghobrial, James D. Griffin, Abdel Kareem Azab, Andrew L. Kung, Paul W. Manley
Publikováno v:
Leukemia. 26:985-990
Drug resistance is a growing area of concern. It has been shown that a small, residual pool of leukemic CD34+ progenitor cells can survive in the marrow microenvironment of chronic myeloid leukemia (CML) patients after years of kinase inhibitor treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b565349816aefd7972ed99495935c8b
https://doi.org/10.1038/leu.2011.360
https://doi.org/10.1038/leu.2011.360
Autor:
James A. Swenberg, Mats Stridsberg, Kevin Flurkey, David E. Harrison, J. McKee Alderman, Sneha B. Naik, Linhong Jing, Urmila Srinivas, Terry P. Combs, Xian Chen, Natasha L. Brooks, Jonathan M. Gutierrez, Carol E. Parker, Simon Klebanov, Rod Bronson, Kristen B. Ziara, Gunnar Boysen
Publikováno v:
Experimental Gerontology. 44:26-33
Pit1 null (Snell dwarf) and Proph1 null (Ames dwarf) mutant mice lack GH, PRL and TSH. Snell and Ames dwarf mice also exhibit reduced IGF-I, resistance to cancer and a longer lifespan than control mice. Endogenous glucose production during fasting is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c9462a27a0b0b955bd742ec2a11579
https://doi.org/10.1016/j.exger.2008.05.014
https://doi.org/10.1016/j.exger.2008.05.014
Autor:
Matthew K. Waldor, Gang Fang, Jennifer M. Ritchie, Stavroula K. Hatzios, Eric E. Schadt, Rod Bronson, Brigid M. Davis, Diana Munera
Publikováno v:
Nature communications
The outbreak of diarrhoea and haemolytic uraemic syndrome that occurred in Germany in 2011 was caused by a Shiga toxin-producing enteroaggregative Escherichia coli (EAEC) strain. The strain was classified as EAEC owing to the presence of a plasmid (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b114b0fd8fa80232f3d2d84dc387af
https://doi.org/10.1038/ncomms4080
https://doi.org/10.1038/ncomms4080
Autor:
Louis N. Martin, Peter J. Dailey, Harold M. McClure, Michael F. Greene, Rod Bronson, Timothy W. Baba, Dominique G. Penninck, Nancy B. Ray, Vladimir Liska, Anis H. Khimani, Ruth M. Ruprecht
Publikováno v:
Nature Medicine. 5:194-203
A substantial risk in using live attenuated, multiply deleted viruses as vaccines against AIDS is their potential to induce AIDS. A mutant of the simian immunodeficiency virus (SIV) with large deletions in nef and vpr and in the negative regulatory e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9273f84c65916cc8c8a9bfbb412996e1
https://doi.org/10.1038/5557
https://doi.org/10.1038/5557
Publikováno v:
Blood. 90:4610-4619
Jaundiced mice, ja/ja, suffer from a severe hemolytic anemia caused by a complete deficiency of erythroid β-spectrin. We used these mice as a model to investigate the pathophysiological consequences of the deficiency, including the effects in the no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dd34d8b74e97c744d37840ccc2fa7e
https://doi.org/10.1182/blood.v90.11.4610
https://doi.org/10.1182/blood.v90.11.4610
Publikováno v:
Proceedings of the National Academy of Sciences. 94:12880-12885
All nucleated cells make phosphatidylcholine via the CDP-choline pathway. Liver has an alternative pathway in which phosphatidylcholine is made by methylation of phosphatidylethanolamine catalyzed by phosphatidylethanolamine N -methyltransferase (PEM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8335cd9d5e73f810a5e1f064a8cd8c
https://doi.org/10.1073/pnas.94.24.12880
https://doi.org/10.1073/pnas.94.24.12880
Autor:
Yong Seok Jeong, Rod Bronson, Timothy W. Baba, Dominique Pennick, Michael F. Greene, Ruth M. Ruprecht
Publikováno v:
Science. 267:1820-1825
Adult macaques do not develop disease after infection with a nef deletion mutant of the simian immunodeficiency virus (SIV) and are protected against challenge with pathogenic virus. This finding led to the proposal to use nef-deleted viruses as live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee7bc36aa0a476b6f552817f9fa657b
https://doi.org/10.1126/science.7892606
https://doi.org/10.1126/science.7892606
Autor:
Joshua Leeman, Michael Berman, Yi Luo, Sara Abromson-Leeman, Rod Bronson, Rebecca J Leeman, Martin E. Dorf
Two distinct clinical phenotypes of experimental autoimmune encephalomyelitis are observed in BALB interferon-gamma knockout mice immunized with encephalitogenic peptides of myelin basic protein. Conventional disease, characterized by ascending weakn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09e18fb056b9cd699abf4e128b3e3b2
https://europepmc.org/articles/PMC1618652/
https://europepmc.org/articles/PMC1618652/
Autor:
Stefan Przyborski, Jacqueline H. Finger, Susan L. Ackerman, Rod Bronson, Belinda S. Harris, Kenneth O. Johnson
Migrating axons require the correct presentation of guidance molecules, often at multiple choice points, to find their target. Netrin 1, a bifunctional cue involved in both attracting and repelling axons, is involved in many cell migration and axon p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4a8c139c0da05c8de354f0596c0dd4
https://europepmc.org/articles/PMC6758749/
https://europepmc.org/articles/PMC6758749/