Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rocky Diegmiller"'
Autor:
Rocky Diegmiller, Laurent Salphati, Bruno Alicke, Timothy R. Wilson, Thomas J. Stout, Marc Hafner
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 9, Pp 1183-1193 (2022)
Abstract A major challenge in oncology drug development is to elucidate why drugs that show promising results in cancer cell lines in vitro fail in mouse studies or human trials. One of the fundamental steps toward solving this problem is to better p
Externí odkaz:
https://doaj.org/article/a27b16f4e3af4e099d40f81f20515d08
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 2, p e1010875 (2023)
From insects to mammals, oocytes and sperm develop within germline cysts comprising cells connected by intercellular bridges (ICBs). In numerous insects, formation of the cyst is accompanied by growth of the fusome-a membranous organelle that permeat
Externí odkaz:
https://doaj.org/article/187de88fa1344fd6b087477f6b939520
Autor:
Rocky Diegmiller, Lun Zhang, Marcio Gameiro, Justinn Barr, Jasmin Imran Alsous, Paul Schedl, Stanislav Y Shvartsman, Konstantin Mischaikow
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008711 (2021)
Since the seminal 1961 paper of Monod and Jacob, mathematical models of biomolecular circuits have guided our understanding of cell regulation. Model-based exploration of the functional capabilities of any given circuit requires systematic mapping of
Externí odkaz:
https://doaj.org/article/62be1c007851437bbadeaa8318e00f40
Publikováno v:
Interface Focus
Small cell clusters exhibit numerous phenomena typically associated with complex systems, such as division of labour and programmed cell death. A conserved class of such clusters occurs during oogenesis in the form of germline cysts that give rise to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084fbdbf2f331b5eea271b1dea44390d
https://europepmc.org/articles/PMC9184967/
https://europepmc.org/articles/PMC9184967/
Publikováno v:
PLOS Computational Biology. 19:e1010875
From insects to mammals, oocytes ad sperm develop within germline cysts comprising cells connected by intercellular bridges (ICBs). In numerous insects, formation of the cyst is accompanied by growth of the fusome – a membranous that permeates the
Autor:
Tomer Stern, Rocky Diegmiller, Caroline A. Doherty, Jasmin Imran Alsous, Stanislav Y. Shvartsman
Publikováno v:
Development
Size is a fundamental feature of living entities and is intimately tied to their function. Scaling laws, which can be traced to D'Arcy Thompson and Julian Huxley, have emerged as a powerful tool for studying regulation of the growth dynamics of organ
Publikováno v:
Biophys J
Problems with networks of coupled oscillators arise in multiple contexts, commonly leading to the question about the dependence of network dynamics on network structure. Previous work has addressed this question in Drosophila oogenesis, in which stab
Autor:
Justinn Barr, Konstantin Mischaikow, Paul Schedl, Stanislav Y. Shvartsman, Rocky Diegmiller, Jasmin Imran Alsous, Marcio Gameiro, Lun Zhang
Publikováno v:
PLoS Computational Biology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Computational Biology, Vol 17, Iss 2, p e1008711 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Computational Biology, Vol 17, Iss 2, p e1008711 (2021)
Since the seminal 1961 paper of Monod and Jacob, mathematical models of biomolecular circuits have guided our understanding of cell regulation. Model-based exploration of the functional capabilities of any given circuit requires systematic mapping of
Publikováno v:
Biophysical journal. 115(1)
Intracellular symmetry breaking plays a key role in wide range of biological processes, both in single cells and in multicellular organisms. An important class of symmetry-breaking mechanisms relies on the cytoplasm/membrane redistribution of protein
Autor:
Avathamsa Athirasala, Joe Swift, Jerome Irianto, Dennis E. Discher, Kyle R. Spinler, Rocky Diegmiller, Irena L. Ivanovska, Jae-Won Shin, Takamasa Harada, P.C. Dave P. Dingal
Publikováno v:
The Journal of Cell Biology
Lamins impede 3D migration but also promote survival against migration-induced stresses.
Cell migration through solid tissue often involves large contortions of the nucleus, but biological significance is largely unclear. The nucleoskeletal prot
Cell migration through solid tissue often involves large contortions of the nucleus, but biological significance is largely unclear. The nucleoskeletal prot