Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5- HT1A receptor activation.

Autor: Bolognini, D¹, Rock, EM², Cluny, NL³, Cascio, MG¹, Limebeer, CL², Duncan, M⁴, Stott, CG⁴, Javid, FA⁵, Parker, LA², Pertwee, RG¹

Publikováno v: British Journal of Pharmacology. Mar2013, Vol. 168 Issue 6, p1456-1470. 15p. 1 Diagram, 1 Chart, 8 Graphs.

Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus.

Autor: Rock, EM¹, Bolognini, D², Limebeer, CL¹, Cascio, MG², Anavi-Goffer, S², Fletcher, PJ³, Mechoulam, R⁴, Pertwee, RG², Parker, LA¹

Publikováno v: British Journal of Pharmacology. Apr2012, Vol. 165 Issue 8, p2620-2634. 15p. 2 Black and White Photographs, 9 Graphs.

Erratum: The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat (Psychopharmacology DOI: 10.1007/s00213-007-0970-1)

Autor: Rock, EM, Limebeer, CL, Mechoulam, R, Piomelli, D, Parker, LA

Publikováno v: Rock, EM; Limebeer, CL; Mechoulam, R; Piomelli, D; & Parker, LA. (2011). Erratum: The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat (Psychopharmacology DOI: 10.1007/s00213-007-0970-1). Psychopharmacology, 216(1), 149. doi: 10.1007/s00213-011-2332-2. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1r98m0t6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::d2a7b801e2f1033cd7f1561ef208392b
http://www.escholarship.org/uc/item/1r98m0t6

The anti-nausea effects of CB1 agonists are mediated by an action at the visceral insular cortex.

Autor: Limebeer CL, Rock EM, Mechoulam R, Parker LA, Limebeer, C L, Rock, E M, Mechoulam, R, Parker, L A

Publikováno v: British Journal of Pharmacology; Nov2012, Vol. 167 Issue 5, p1126-1136, 11p

Cannabinoids suppress acute and anticipatory nausea in preclinical rat models of conditioned gaping.

Autor: Parker, LA, Rock, EM, Sticht, MA, Wills, KL, Limebeer, CL

Publikováno v: Clinical Pharmacology & Therapeutics; Jun2015, Vol. 97 Issue 6, p559-561, 3p