N,N-Dialkyl-dipeptidylamines as novel N-type calcium channel blockers

Autor: Hu, L.-Y., Ryder, T. R., Rafferty, M. F., Cody, W. L., Lotarski, S. M., Miljanich, G. P., Millerman, E., Rock, D. M., Song, Y., Stoehr, S. J.

Publikováno v: Bioorganic & Medicinal Chemistry Letters; 1999, Vol. 9 Issue: 6 p907-912, 6p

4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine:  A Novel, Potent, and Selective NR1/2B NMDA Receptor Antagonist

Autor: Zhou, Z.-L., Cai, S. X., Whittemore, E. R., Konkoy, C. S., Espitia, S. A., Tran, M., Rock, D. M., Coughenour, L. L., Hawkinson, J. E., Boxer, P. A., Bigge, C. F., Wise, L. D., Weber, E., Woodward, R. M., Keana, J. F. W.

Publikováno v: Journal of Medicinal Chemistry; July 29, 1999, Vol. 42 Issue: 15 p2993-3000, 8p

The polyamine spermine has multiple actions on N-methyl-D-aspartate receptor single-channel currents in cultured cortical neurons.

Autor: Rock, D M, Macdonald, R L

Publikováno v: Molecular Pharmacology; January 1992, Vol. 41 Issue: 1 p83-88, 6p

Gabapentin actions on ligand- and voltage-gated responses in cultured rodent neurons

Autor: Rock, D. M., Kelly, K. M., Macdonald, R. L.

Publikováno v: Epilepsy Research; 1993, Vol. 16 Issue: 2 p89-89, 1p

Structure-activity relationship at the leucine side chain in a series of N,N-dialkyldipeptidyl-amines as N-type calcium channel blockers.

Autor: Ryder TR; Department of Chemistry, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, Ann Arbor, MI 48105, USA., Hu LY, Rafferty MF, Lotarski SM, Rock DM, Stoehr SJ, Taylor CP, Weber ML, Miljanich GP, Millerman E, Szoke BG

Publikováno v: Drug design and discovery [Drug Des Discov] 2000; Vol. 16 (4), pp. 317-22.