Výsledky vyhledávání - "Rocio Rosas Alonso"

Akademický článek

Advancing pharmacogenetic testing in a tertiary hospital: a retrospective analysis after 10 years of activity

Autor: Stefan Stewart, Jose Manuel Dodero-Anillo, Javier Guijarro-Eguinoa, Pedro Arias, Arturo Gómez López De Las Huertas, Enrique Seco-Meseguer, Irene García-García, Elena Ramírez García, Carlos Rodríguez-Antolín, Antonio J. Carcas, Sonia Rodriguez-Novoa, Rocio Rosas-Alonso, Alberto M. Borobia

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

The field of pharmacogenetics (PGx) holds great promise in advancing personalized medicine by adapting treatments based on individual genetic profiles. Despite its benefits, there are still economic, ethical and institutional barriers that hinder its

Externí odkaz: https://doaj.org/article/8d142befa8af47ffaafc39bc0315062c

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Identification of miR-151a as a novel endogenous control for small extracellular vesicle cargo normalization in human cancer

Autor: Miranda Burdiel, Julia Jimenez, Carlos Rodriguez-Antolin, Alvaro Garcia-Guede, Olga Pernia, Ana Sastre, Rocio Rosas-Alonso, Julian Colmenarejo, Carmen Rodriguez-Jiménez, Maria Dolores Diestro, Virginia Martinez-Marin, Oliver Higuera, Patricia Cruz, Itsaso Losantos-Garcia, Olga Vera, Hector Peinado, Javier de Castrro, Inmaculada Ibañez de Caceres

Background: Small extracellular vesicles (sEVs) in the blood of cancer patients contain higher amounts of tumor markers than those identified as free-circulating. miRNAs have significant biomedical relevance due to their high stability and feasible d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b60dab3b4f5d41f89a7fffd37ae2d66b
https://doi.org/10.21203/rs.3.rs-2731367/v1

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Impact of dose adjustment of fluoropyrimidines on toxicity in patients with DPD-deficient colorectal cancer: A single-center experience

Autor: Daniel Martinez-Perez, Ismael Ghanem, Rocio Rosas-Alonso, Pedro Arias, Sonia Rodriguez-Novoa, Alberto Borobia, David Viñal, Iciar Ruiz-Gutierrez, Diego Jiménez-Bou, Nuria Rodriguez Salas, Jaime Feliu Batlle

Publikováno v: Journal of Clinical Oncology. 41:94-94

94 Background: Fluoropyrimidines (FPs) are the chemotherapy backbone for most patients with CRC. FPs are metabolized by dihydropyrimidine dehydrogenase (DPD). Current guidelines recommend measuring DPD activity before chemotherapy administration to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::927ba8726181a1b535a3b92f0de5f9a4
https://doi.org/10.1200/jco.2023.41.4_suppl.94

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Additional file 2 of Clinical validation of a novel quantitative assay for the detection of MGMT methylation in glioblastoma patients

Autor: Rocio Rosas-Alonso, Colmenarejo-Fernandez, Julian, Pernia, Olga, Rodriguez-Antolín, Carlos, Esteban, Isabel, Ghanem, Ismael, Sanchez-Cabrero, Dario, Losantos-Garcia, Itsaso, Palacios-Zambrano, Sara, Moreno-Bueno, Gema, Castro, Javier De, Martinez-Marin, Virginia, Ibanez-De-Caceres, Inmaculada

Additional file 2: Supplementary Figure 2. Examples of MSP and dp_qMSP amplifications from the same samples. A MSP samples are shown in duplicate U: Unmethylated reaction, M: methylated reaction, C- : Unmethylated control sample and C+: IVD control s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242dc3dc30c10b9d491d36c952e65085

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Additional file 1 of Clinical validation of a novel quantitative assay for the detection of MGMT methylation in glioblastoma patients

Additional file 1: Supplementary Figure 1. Uncropped gel from Fig. 2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1079b61f88f7e377dd088f5c1d5921b6

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Additional file 3 of Clinical validation of a novel quantitative assay for the detection of MGMT methylation in glioblastoma patients

Additional file 3: Supplementary Figure 3. Agarose gel with the MGMT promoter amplification of five samples with discrepancies between MSP and dp_qMSP. It has been performed in a collaborative center (MD Anderson Madrid) with an alternative methodolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ec6e7df11d687fb257904fadfa3a9e

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Next generation sequencing (NGS) as a useful tool to identify clinically meaningful somatic and germinal variants in the early stages of non-small-cell lung cancer (NSCLC)

Autor: Virginia Martínez, Angela Del Pozo Mate, Prudencio Diaz Agero, Patricia Cruz, Inmaculada Ibáñez de Cáceres, Kristina Ibáñez, Julián Nevado Blanco, Javier de Castro, Oliver Higuera Gómez, Olga Pernía, Rocio Rosas Alonso, Carlos Rodríguez Antolín, Elena Vallespin Garcia

Publikováno v: Journal of Clinical Oncology. 34:e20068-e20068

e20068Background: This is an innovative project that aims to implement NGS to detect new genetic alterations in the early stages of NSCLC and their potential role as biomarkers of the tumoral evolu...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cdb417c8856b40254961d82637a891fb
https://doi.org/10.1200/jco.2016.34.15_suppl.e20068

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