Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Rocio Rodriguez-Melendez"'
Publikováno v:
The Journal of Nutrition. 140:1546-1551
Holocarboxylase synthetase (HCS) catalyzes the covalent binding of biotin to carboxylases and histones. In mammals, the expression of HCS depends on biotin, but the mechanism of regulation is unknown. Here we tested the hypothesis that microRNA (miR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74f96098db64d6dac881049c28b962e7
https://doi.org/10.3945/jn.110.126359
https://doi.org/10.3945/jn.110.126359
Publikováno v:
The Journal of Nutritional Biochemistry. 17:250-256
Eukaryotes convert riboflavin to flavin adenine dinucleotide, which serves as a coenzyme for glutathione reductase and other enzymes. Glutathione reductase mediates the regeneration of reduced glutathione, which plays an important role in scavenging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90d49a2a5a4557b41cbbe78f2a81604
https://doi.org/10.1016/j.jnutbio.2005.05.004
https://doi.org/10.1016/j.jnutbio.2005.05.004
Publikováno v:
The Journal of Nutrition. 135:1659-1666
Biotin affects the abundance of mRNA coding for approximately 10% of genes expressed in human-derived hepatocarcinoma (HepG2) cells. Here, we determined whether effects of biotin on gene expression are associated with changes in the abundance of dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c7c4e6b4b65055cbae63e8c8e5e1c6c
https://doi.org/10.1093/jn/135.7.1659
https://doi.org/10.1093/jn/135.7.1659
Publikováno v:
The Journal of Nutrition. 134:2222-2228
DNA microarray studies provided evidence that biotin supplementation increases the abundance of mRNA encoding cytochrome P(450) 1B1 (CYP1B1) in human lymphocytes. CYP1B1 hydroxylates procarcinogens, generating electrophilic mutagens. Here, we sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490d412adaac440c6b23f7a927b68b7b
https://doi.org/10.1093/jn/134.9.2222
https://doi.org/10.1093/jn/134.9.2222
Publikováno v:
International Journal for Vitamin and Nutrition Research. 74:209-216
Members of the NF-kappaB family of transcription factors cause transcriptional activation of anti-apoptotic genes. Here we determined whether survival of biotin-deficient cells is mediated by nuclear translocation of NF-kappaB. Human T (Jurkat) cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3400fbba5fca01e9791c81c1e9a5f8
https://doi.org/10.1024/0300-9831.74.3.209
https://doi.org/10.1024/0300-9831.74.3.209
Publikováno v:
The Journal of Nutritional Biochemistry. 14:680-690
In mammals, biotin serves as coenzyme for four carboxylases, which play essential roles in the metabolism of glucose, amino acids, and fatty acids. Biotin deficiency causes decreased rates of cell proliferation, impaired immune function, and abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa6f6a534abf3bff5387b026652ae84
https://doi.org/10.1016/j.jnutbio.2003.07.001
https://doi.org/10.1016/j.jnutbio.2003.07.001
Publikováno v:
The Journal of Nutrition. 133:1259-1264
In mammals, biotin serves as a coenzyme for carboxylases such as propionyl-CoA carboxylase. The expression of genes encoding interleukin-2 (IL-2) and IL-2 receptor (IL-2R)gamma also depends on biotin. Biotin metabolites are structurally similar to bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567a90fb021ddbbb2849f620d1d1fa45
https://doi.org/10.1093/jn/133.5.1259
https://doi.org/10.1093/jn/133.5.1259
Holocarboxylase synthetase (HLCS) catalyzes the covalent binding of biotin to both carboxylases in extranuclear structures and histones in cell nuclei, thereby mediating important roles in intermediary metabolism, gene regulation, and genome stabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c611ea0671f5f9c5c945a9acc92d029
https://europepmc.org/articles/PMC3159853/
https://europepmc.org/articles/PMC3159853/
Publikováno v:
The Journal of nutritional biochemistry. 23(6)
Holocarboxylase synthetase (HCS) plays an essential role in catalyzing the biotinylation of carboxylases and histones. Biotinylated carboxylases are important for the metabolism of glucose, lipids and leucine; biotinylation of histones plays importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9f56458f377208af76ac245ab7e5af
https://pubmed.ncbi.nlm.nih.gov/21764280
https://pubmed.ncbi.nlm.nih.gov/21764280
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21f5c7e653b256accd9035fd07cd4509
https://doi.org/10.1096/fasebj.24.1_supplement.550.2
https://doi.org/10.1096/fasebj.24.1_supplement.550.2