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Autor:
Angélica Lozano-Lunar, Rocio Otero, José Ignacio Álvarez, José Ramón Jiménez, José María Fernández-Rodríguez
Publikováno v:
Applied Clay Science. 238:106938
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd983661ae158ffd5eca947c5b9d28c
https://doi.org/10.1016/j.clay.2023.106938
https://doi.org/10.1016/j.clay.2023.106938
Autor:
Juan Corredoira Sánchez, Blanca Ayuso García, Eva María Romay Lema, María José García-Pais, Ana I. Rodríguez-Macias, Patricia Capón González, Rocio Otero López, Ramón Rabuñal Rey, Pilar Alonso García
Publikováno v:
Enfermedades Infecciosas y Microbiología Clínica.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8836d10bb5c6f41567d748890af2cd
https://doi.org/10.1016/j.eimc.2022.06.010
https://doi.org/10.1016/j.eimc.2022.06.010
Autor:
Sachiko Yamada, Nobutaka Numoto, Makoto Makishima, Antonio Mouriño, Hiroaki Tokiwa, Teikichi Ikura, Michiyasu Ishizawa, Nobutoshi Ito, Rocio Otero
Publikováno v:
Journal of Medicinal Chemistry. 61:6658-6673
Both 25R- and 25S-25-adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D3 (4a and 4b) were stereoselectively synthesized by a Pd(0)-catalyzed ring closure and Suzuki–Miyaura coupling between enol-triflate 7 and alkenyl-boronic ester 8. The 25S i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cac2611a5462b634aa76a0d7ecd7e02
https://doi.org/10.1021/acs.jmedchem.8b00427
https://doi.org/10.1021/acs.jmedchem.8b00427
Autor:
Rocio Otero, Patricia González-Berdullas, Miguel A. Maestro, Rita Sigüeiro, Julian Loureiro, Antonio Mouriño
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 173:86-88
A new approach to 19-nor-A-ring phosphine oxide 5 together with a convergent synthesis of the vitamin D3 analogue 1α,25-dihydroxy-19-norvitamin D3 (3) have been developed. The 19-nor-A-ring is constructed from (S)-carvone. The triene system is assem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78785d8c2d2eaeb3ff191eb1c063318b
https://doi.org/10.1016/j.jsbmb.2016.08.008
https://doi.org/10.1016/j.jsbmb.2016.08.008
Autor:
Rocio, Otero, Michiyasu, Ishizawa, Nobutaka, Numoto, Teikichi, Ikura, Nobutoshi, Ito, Hiroaki, Tokiwa, Antonio, Mouriño, Makoto, Makishima, Sachiko, Yamada
Publikováno v:
Journal of medicinal chemistry. 61(15)
Both 25 R- and 25 S-25-adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0f8ef41e112695914688d49af2a4e2d
https://pubmed.ncbi.nlm.nih.gov/29989817
https://pubmed.ncbi.nlm.nih.gov/29989817
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 148:31-33
The first synthesis of 1α,25-dihydroxy-3-epi-vitamin D2 is described. Key steps of the synthesis entail the construction of the triene unit by a Pd-catalyzed ring closure of an enol-triflate (A-ring fragment) followed by a Suzuki–Miyaura coupling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4016543d4f200493f3d6da12513bed0a
https://doi.org/10.1016/j.jsbmb.2014.10.008
https://doi.org/10.1016/j.jsbmb.2014.10.008
Autor:
Rita Sigüeiro, Samuel Seoane, Rocio Otero, Miguel A. Maestro, Anna Y. Belorusova, Antonio Mouriño, Natacha Rochel, Roman Perez-Fernandez
Publikováno v:
Chemical Science
Chemical Science, The Royal Society of Chemistry, 2016, 7 (2), pp.1033-1037. ⟨10.1039/c5sc03084f⟩
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Chemical Science, The Royal Society of Chemistry, 2016, 7 (2), pp.1033-1037. ⟨10.1039/c5sc03084f⟩
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
The vitamin D nuclear receptor (VDR) is a potential target for cancer therapy. It is expressed in many tumors and its ligand shows anticancer actions. To combine these properties with the application of boron neutron capture therapy (BNCT), we design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736ff7ed88d402a091423d79ab703555
https://hal.archives-ouvertes.fr/hal-03679159
https://hal.archives-ouvertes.fr/hal-03679159
Autor:
T. Regueira, Borja López-Pérez, Roman Perez-Fernandez, Miguel A. Maestro, Rita Sigüeiro, Patricia González-Berdullas, A. Álvarez, Samuel Seoane, Rocio Otero, A. Mouriño, Diego M. Carballa
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 144:204-206
An efficient convergent synthesis of nonadeuterated 1α,25-dihydroxyvitamin D2 (1) by Pd(0)-catalyzed coupling between the boronate ester (upper fragment) and the enol triflate (A-ring fragment) is described. This article is part of a Special Issue e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30242309f44ea5636e2c5ae17f8a0fd8
https://doi.org/10.1016/j.jsbmb.2013.10.025
https://doi.org/10.1016/j.jsbmb.2013.10.025
Publikováno v:
ChemInform. 46
The first synthesis of 1α,25-dihydroxy-3-epi-vitamin D2 is described. Key steps of the synthesis entail the construction of the triene unit by a Pd-catalyzed ring closure of an enol-triflate (A-ring fragment) followed by a Suzuki–Miyaura coupling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c396b9f3700bdd1f1171f220590ce336
https://doi.org/10.1002/chin.201521294
https://doi.org/10.1002/chin.201521294