Zobrazeno 1 - 10
of 360
pro vyhledávání: '"Rocio Garcia Carbonero"'
Autor:
Maria Carmen Riesco-Martinez, Jaume Capdevila, Vicente Alonso, Paula Jimenez-Fonseca, Alex Teule, Enrique Grande, Isabel Sevilla, Marta Benavent, Teresa Alonso-Gordoa, Ana Custodio, Beatriz Anton-Pascual, Jorge Hernando, Eduardo Polo, Oscar Alfredo Castillo-Trujillo, Arantza Lamas-Paz, Ana Teijo, Yolanda Rodriguez-Gil, Beatriz Soldevilla, Rocio Garcia-Carbonero
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The prognosis of patients with advanced high-grade (G3) digestive neuroendocrine neoplasms (NENs) is rather poor. The addition of immune checkpoint inhibition to platinum-based chemotherapy may improve survival. NICE-NEC (NCT03980925) is a s
Externí odkaz:
https://doaj.org/article/6981a3198f934da4bebd41d0dfe4b108
Autor:
Marco Donatello Delcuratolo, Andrea Modrego-Sánchez, Maristella Bungaro, Beatriz Antón-Pascual, Santiago Teran, Valentina Dipace, Silvia Novello, Rocio Garcia-Carbonero, Francesco Passiglia, Cristina Graválos-Castro
Publikováno v:
Journal of Molecular Pathology, Vol 4, Iss 3, Pp 128-155 (2023)
Colorectal cancer is one of the most prevalent cancers nowadays. In the metastatic setting, diagnosis and treatment have relied on tumor tissue analysis. However, the different limitations of this approach have recently opened the door to the introdu
Externí odkaz:
https://doaj.org/article/ef5052c039fe40a7b4f817d3098b8874
Autor:
Ariana Huebner, James R. M. Black, Francesca Sarno, Roberto Pazo, Ignacio Juez, Laura Medina, Rocio Garcia-Carbonero, Carmen Guillén, Jaime Feliú, Carolina Alonso, Carlota Arenillas, Ana Belén Moreno-Cárdenas, Helena Verdaguer, Teresa Macarulla, Manuel Hidalgo, Nicholas McGranahan, Rodrigo A. Toledo
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Liquid biopsies and the dynamic tracking of somatic mutations within circulating tumour DNA (ctDNA) can provide insight into the dynamics of cancer evolution and the intra-tumour heterogeneity that fuels treatment resistance. Howe
Externí odkaz:
https://doaj.org/article/21716a2b02ec46eb8dbe1a817c4a0bab
Autor:
Beatriz Soldevilla, Alberto Lens‐Pardo, Paula Espinosa‐Olarte, Carlos Carretero‐Puche, Sonia Molina‐Pinelo, Carlos Robles, Marta Benavent, Lourdes Gomez‐Izquierdo, Marta Fierro‐Fernández, Patricia Morales‐Burgo, Paula Jimenez‐Fonseca, Beatriz Anton‐Pascual, Yolanda Rodriguez‐Gil, Ana Teijo‐Quintans, Anna La Salvia, Beatriz Rubio‐Cuesta, Maria C. Riesco‐Martínez, Rocio Garcia‐Carbonero
Publikováno v:
Molecular Oncology, Vol 17, Iss 4, Pp 582-597 (2023)
Neuroendocrine neoplasms (NENs) are mutationally quiet (low number of mutations/Mb), and epigenetic mechanisms drive their development and progression. We aimed at comprehensively characterising the microRNA (miRNA) profile of NENs, and exploring dow
Externí odkaz:
https://doaj.org/article/96f622ea83a04182b9b9cbef9fb1d2ac
Autor:
Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Joan Maurel, Rocio Garcia-Carbonero, Jaume Capdevila, Laura G-Pastrián, Marta Mendiola, Cristina Peña, Rocío López-Vacas, Miriam Cuatrecasas, Pilar García-Alfonso, Ricardo Ramos-Ruiz, Carlos Llorens, Ismael Ghanem, Carles Conill, Victoria Heredia-Soto, Ángel Campos-Barros, Juan Ángel Fresno Vara, Jaime Feliu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Squamous cell carcinoma is the most frequent histologic type of anal carcinoma. The standard of care since the 1970s has been a combination of 5-fluorouracil, mitomycin C, and radiotherapy. This treatment is very effective in T1/T2 tumors (a
Externí odkaz:
https://doaj.org/article/d4fe26f9fdff4908953ce34c605cf410
Autor:
Jaime Feliu, Rocio Garcia‐Carbonero, Jaume Capdevila, Inmaculada Guasch, Vicente Alonso‐Orduna, Carlos Lopez, Pilar Garcia‐Alfonso, Carmen Castanon, Isabel Sevilla, Laura Cerezo, Carles Conill, Begona Quintana‐Angel, Maria E. Sanchez, Ismael Ghanem, Marta Martin‐Richard, Miriam Lopez‐Gomez, Ana Leon, Monica Caro, Teresa Fernandez, Joan Maurel
Publikováno v:
Cancer Medicine, Vol 9, Iss 3, Pp 1008-1016 (2020)
Abstract Aim VITAL, a phase II single‐arm study, aimed to evaluate efficacy and safety of panitumumab addition to 5‐fluorouracil (5‐FU), mitomycin‐C (MMC) and radiotherapy (RT) in patients with localized squamous cell carcinoma of the anal ca
Externí odkaz:
https://doaj.org/article/f408da2c06104b189853b1f8992e4d37
Autor:
Gabriel Capellá, Francisco X Real, Marta Gil-Martin, Rocio Garcia-Carbonero, Rafael Moreno, Ramon Alemany, Martí Farrera-Sal, Ramon Salazar, Teresa Macarulla, Jaime Martinez de Villarreal, Natalia del Pozo, Carmen Guillén-Ponce, Miriam Bazan-Peregrino, Rafael Álvarez, Ana Mato-Berciano, Emma Blasi, Carmen Blasco, Manel Cascallo, Maria C Riesco-Martinez, Helena Verdaguer, Maria Victoria Maliandi, Silvia Torres-Manjon, Marcel Costa, Noemí Vidal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background VCN-01 is an oncolytic adenovirus (Ad5 based) designed to replicate in cancer cells with dysfunctional RB1 pathway, express hyaluronidase to enhance virus intratumoral spread and facilitate chemotherapy and immune cells extravasation into
Externí odkaz:
https://doaj.org/article/f20744c4524742ac8290f86ad68345d4
Autor:
Gabriel Capellá, Rocio Garcia-Carbonero, Rafael Moreno, Ramon Alemany, Alba Rodriguez-Garcia, Ramon Salazar, Mireia M Ginestà, Miriam Bazan-Peregrino, Berta Laquente, Rafael Álvarez, Ana Mato-Berciano, Marta Gimenez-Alejandre, Sara Morgado, Maria V Maliandi, M Carmen Riesco, Mercedes Perez-Carreras, Joan B Gornals, Susana Prados, Sofía Perea, Emma Blasi, Carmen Blasco, Manel Cascallo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/206a9610f35f4268937ff976dcfa5681
Autor:
Antoine Hollebecque, Rocio Garcia-Carbonero, Do-Youn Oh, Emiliano Calvo, Davide Melisi, Teresa Macarulla, Valeria Merz, Erkut Borazanci, Anna Varghese, Camilla Zecchetto, Yumin Zhao, Ivelina Gueorguieva, Michael Man, Shawn T Estrem, Karim A Benhadji, Emin Avsar, Susan C Guba
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background We assessed the safety, efficacy, and pharmacokinetics of the transforming growth factor beta (TGFβ) receptor inhibitor galunisertib co-administered with the anti-programmed death-ligand 1 (PD-L1) antibody durvalumab in recurrent/refracto
Externí odkaz:
https://doaj.org/article/c175cf79b75445f3ae95a488c7252728
Autor:
Cédric Nesti, Konstantin Bräutigam, Marta Benavent, Laura Bernal, Hessa Boharoon, Johan Botling, Antonin Bouroumeau, Iva Brcic, Maximilian Brunner, Guillaume Cadiot, Maria Camara, Emanuel Christ, Thomas Clerici, Ashley K Clift, Hamish Clouston, Lorenzo Cobianchi, Jarosław B Ćwikła, Kosmas Daskalakis, Andrea Frilling, Rocio Garcia-Carbonero, Simona Grozinsky-Glasberg, Jorge Hernando, Valérie Hervieu, Johannes Hofland, Pernille Holmager, Frediano Inzani, Henning Jann, Paula Jimenez-Fonseca, Enes Kaçmaz, Daniel Kaemmerer, Gregory Kaltsas, Branislav Klimacek, Ulrich Knigge, Agnieszka Kolasińska-Ćwikła, Walter Kolb, Beata Kos-Kudła, Catarina Alisa Kunze, Stefania Landolfi, Stefano La Rosa, Carlos López López, Kerstin Lorenz, Maurice Matter, Peter Mazal, Claudia Mestre-Alagarda, Patricia Morales del Burgo, Els J M Nieveen van Dijkum, Kira Oleinikov, Lorenzo A Orci, Francesco Panzuto, Marianne Pavel, Marine Perrier, Henrik Mikael Reims, Guido Rindi, Anja Rinke, Maria Rinzivillo, Xavier Sagaert, Ilker Satiroglu, Andreas Selberherr, Alexander R Siebenhüner, Margot E T Tesselaar, Michael J Thalhammer, Espen Thiis-Evensen, Christos Toumpanakis, Timon Vandamme, José G van den Berg, Alessandro Vanoli, Marie-Louise F van Velthuysen, Chris Verslype, Stephan A Vorburger, Alessandro Lugli, John Ramage, Marcel Zwahlen, Aurel Perren, Reto M Kaderli
Publikováno v:
The Lancet Oncology, 24(2), 187-194. Lancet Publishing Group
The lancet oncology
The lancet oncology
BACKGROUND Awareness of the potential global overtreatment of patients with appendiceal neuroendocrine tumours (NETs) of 1-2 cm in size by performing oncological resections is increasing, but the rarity of this tumour has impeded clear recommendation