Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rocío Sotillo"'
Autor:
Guillermo de Cárcer, Sharavan Vishaan Venkateswaran, Lorena Salgueiro, Aicha El Bakkali, Kalman Somogyi, Konstantina Rowald, Pablo Montañés, Manuel Sanclemente, Beatriz Escobar, Alba de Martino, Nicholas McGranahan, Marcos Malumbres, Rocío Sotillo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
PLK1 is a mitotic regulator overexpressed in cancer; however, whether this overexpression causally contributes to tumor development is unclear. Here the authors produce an inducible mouse model to overexpress PLK1 and show that actually this can act
Externí odkaz:
https://doaj.org/article/624e442f805148c5bac60f63e764f010
Autor:
Olaf Hardt, Zuzana Storchová, Andreas Bosio, Rocío Sotillo, Charles Swanton, Erich A. Nigg, Conrad von Schubert, Cristina Viganó, David Agorku, Sharavan V. Venkateswaran, Katarzyna Seget, Lalitha S.Y. Nanduri, Patrícia H. Domingues
Expression of CD230 upon serum-starvation in parental and trisomic cells. Representative dot plots of FSC-A vs CD230-A for HCT116 parental and HCT116 trisomic clones - 18/3 cl2 and 21/3 cl1 and 3 - cultured under normal conditions (10% FBS, control)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eaa255ceb509dbfb703b0b818e3d11f
https://doi.org/10.1158/0008-5472.22413861
https://doi.org/10.1158/0008-5472.22413861
Autor:
Olaf Hardt, Zuzana Storchová, Andreas Bosio, Rocío Sotillo, Charles Swanton, Erich A. Nigg, Conrad von Schubert, Cristina Viganó, David Agorku, Sharavan V. Venkateswaran, Katarzyna Seget, Lalitha S.Y. Nanduri, Patrícia H. Domingues
Supplementary Tables S1-S3. Detailed description of antibodies used for the cell surface screenings performed with the initial 300 antibody high-throughput screening panel (S1), the 49-marker validation screening panel (S2), and the 36-marker mouse t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef5bcceba2a0a0efdc5a9761735bde2
https://doi.org/10.1158/0008-5472.22413855
https://doi.org/10.1158/0008-5472.22413855
Autor:
Olaf Hardt, Zuzana Storchová, Andreas Bosio, Rocío Sotillo, Charles Swanton, Erich A. Nigg, Conrad von Schubert, Cristina Viganó, David Agorku, Sharavan V. Venkateswaran, Katarzyna Seget, Lalitha S.Y. Nanduri, Patrícia H. Domingues
Description of the Supplementary Files
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ef92019852f7b871d7f010184ede3f
https://doi.org/10.1158/0008-5472.22413858
https://doi.org/10.1158/0008-5472.22413858
Autor:
Olaf Hardt, Zuzana Storchová, Andreas Bosio, Rocío Sotillo, Charles Swanton, Erich A. Nigg, Conrad von Schubert, Cristina Viganó, David Agorku, Sharavan V. Venkateswaran, Katarzyna Seget, Lalitha S.Y. Nanduri, Patrícia H. Domingues
Aneuploidy is a hallmark of most human tumors, but the molecular physiology of aneuploid cells is not well characterized. In this study, we screened cell surface biomarkers of approximately 300 proteins by multiparameter flow cytometry using multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6395c18abcc5710cf7f7ee01ff061457
https://doi.org/10.1158/0008-5472.c.6508839.v1
https://doi.org/10.1158/0008-5472.c.6508839.v1
Autor:
Marcos Malumbres, Amancio Carnero, Mariano Barbacid, Juan Martín-Caballero, Jesús Ruiz-Cabello, Pierre Dubus, Oliver Renner, Rocío Sotillo
Deregulation of the G1-S transition of the cell cycle is a common feature of human cancer. Tumor-associated alterations in this process frequently affect cyclin-dependent kinases (Cdk), their regulators (cyclins, INK4 inhibitors, or p27Kip1), and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577b4dd7a71768f782a011543d78c462
https://doi.org/10.1158/0008-5472.c.6494652
https://doi.org/10.1158/0008-5472.c.6494652
Autor:
Marcos Malumbres, Amancio Carnero, Mariano Barbacid, Juan Martín-Caballero, Jesús Ruiz-Cabello, Pierre Dubus, Oliver Renner, Rocío Sotillo
Supplementary Table 1 from Cooperation between Cdk4 and p27kip1 in Tumor Development: A Preclinical Model to Evaluate Cell Cycle Inhibitors with Therapeutic Activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930b7bc700744088a13b10e1642ee35c
https://doi.org/10.1158/0008-5472.22365336
https://doi.org/10.1158/0008-5472.22365336
Autor:
Théodora Niault, Khaled Hached, Rocío Sotillo, Peter K Sorger, Bernard Maro, Robert Benezra, Katja Wassmann
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1165 (2007)
The spindle assembly checkpoint (SAC) ensures correct separation of sister chromatids in somatic cells and provokes a cell cycle arrest in metaphase if one chromatid is not correctly attached to the bipolar spindle. Prolonged metaphase arrest due to
Externí odkaz:
https://doaj.org/article/8bd4d848e5924c1cad0b23413be343a5
Autor:
Patrícia H, Domingues, Lalitha S Y, Nanduri, Katarzyna, Seget, Sharavan V, Venkateswaran, David, Agorku, Cristina, Viganó, Conrad, von Schubert, Erich A, Nigg, Charles, Swanton, Rocío, Sotillo, Andreas, Bosio, Zuzana, Storchová, Olaf, Hardt
Publikováno v:
Cancer research. 77(11)
Aneuploidy is a hallmark of most human tumors, but the molecular physiology of aneuploid cells is not well characterized. In this study, we screened cell surface biomarkers of approximately 300 proteins by multiparameter flow cytometry using multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41d60ffb63b3d1f4a0d9e7607a46885f
https://pubmed.ncbi.nlm.nih.gov/28377454
https://pubmed.ncbi.nlm.nih.gov/28377454
Autor:
Marcos, Malumbres, Sarah L, Hunt, Rocío, Sotillo, Javier, Martín, Jun, Odajima, Alberto, Martín, Pierre, Dubus, Sagrario, Ortega, Mariano, Barbacid
Publikováno v:
Advances in experimental medicine and biology. 532
Cell cycle progression requires the co-ordinated activation of several kinases, some of which are activated upon the binding of a cyclin subunit. At least four of these so-called cyclin-dependent kinases, namely Cdk4, Cdk6, Cdk2 and Cdk1, have specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8e697e29540ae2c9dff2872c7994cdc
https://pubmed.ncbi.nlm.nih.gov/12908544
https://pubmed.ncbi.nlm.nih.gov/12908544