Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rochelle M. Evans"'
Publikováno v:
Journal of the Endocrine Society
Abstract: Resistance to Thyroid Hormone α (RTHα), a reduced sensitivity to thyroid hormone (T3) in peripheral tissues, is caused by mutations in thyroid hormone receptor α (TRα), a nuclear receptor that regulates gene expression when bound to T3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20a0a4563b6adcf804ca1b2a35f7fdc
https://doi.org/10.1210/js.2019-sat-559
https://doi.org/10.1210/js.2019-sat-559
Autor:
Rochelle M. Evans, Lizabeth A. Allison, Cyril S. Anyetei-Anum, Amanda M. Back, Vincent R. Roggero
Publikováno v:
Mol Cell Endocrinol
The thyroid hormone receptor (TR) undergoes nucleocytoplasmic shuttling, but is primarily nuclear-localized and mediates expression of genes involved in development and homeostasis. Given the proximity of TR acetylation and sumoylation sites to nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326d5fee3cbda630a1dc43fcfbab1e31
https://pubmed.ncbi.nlm.nih.gov/31319097
https://pubmed.ncbi.nlm.nih.gov/31319097
Autor:
Vincent R. Roggero, Rochelle M. Evans, Xiaopeng Sun, Caroline J. Lebegue, Matthew R. Femia, Jibo Zhang, Lizabeth A. Allison
Publikováno v:
J Cell Biochem
The thyroid hormone receptors (TRs) mediate thyroid hormone (T(3))-dependent gene expression. The nuclear import and export signals that direct TR shuttling are well characterized, but little is known about factors modulating nuclear retention. We us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91577cc1ad19f2d155dfd61b85dcf0b
https://pubmed.ncbi.nlm.nih.gov/31692077
https://pubmed.ncbi.nlm.nih.gov/31692077