Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rochelle D. Vergroesen"'
Autor:
Rochelle D. Vergroesen, Linda M. Slot, Barbera D. C. van Schaik, Marvyn T. Koning, Theo Rispens, Antoine H. C. van Kampen, René E. M. Toes, Hans U. Scherer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Many autoimmune diseases are hallmarked by autoreactive B and plasma cell responses that are directly or indirectly involved in disease pathogenesis. These B-cell responses show large variability between diseases, both in terms of the secreted autoan
Externí odkaz:
https://doaj.org/article/c7729ac6a2de4397b5caba227729b47e
Autor:
Linda M Slot, Rochelle D Vergroesen, Priscilla F Kerkman, Ellen Staudinger, Sanne Reijm, Hugo J van Dooren, Ellen I H van der Voort, Tom W J Huizinga, René E M Toes, Hans U Scherer
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247847 (2021)
Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting 1% of the world population. RA is associated with the presence of autoantibodies, of which anti-citrullinated protein antibodies (ACPA) are most prominent. ACPA are produced by citru
Externí odkaz:
https://doaj.org/article/f4bdb0806e0240eab920cc577bc62025
Autor:
Theresa Kissel, Changrong Ge, Lise Hafkenscheid, Joanneke C. Kwekkeboom, Linda M. Slot, Marco Cavallari, Yibo He, Karin A. van Schie, Rochelle D. Vergroesen, Arieke S.B. Kampstra, Sanne Reijm, Gerrie Stoeken-Rijsbergen, Carolien Koeleman, Lennard M. Voortman, Laura H. Heitman, Bingze Xu, Ger J.M. Pruijn, Manfred Wuhrer, Theo Rispens, Tom W.J. Huizinga, Hans Ulrich Scherer, Michael Reth, Rikard Holmdahl, Rene E.M. Toes
Publikováno v:
Science Advances, 8, 6, pp. 1-21
Science Advances, 8, 1-21
Science advances, 8(6):abm1759. American Association for the Advancement of Science
Kissel, T, Ge, C, Hafkenscheid, L, Kwekkeboom, J C, Slot, L M, Cavallari, M, He, Y, van Schie, K A, Vergroesen, R D, Kampstra, A S B, Reijm, S, Stoeken-Rijsbergen, G, Koeleman, C, Voortman, L M, Heitman, L H, Xu, B, Pruijn, G J M, Wuhrer, M, Rispens, T, Huizinga, T W J, Scherer, H U, Reth, M, Holmdahl, R & Toes, R E M 2022, ' Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation ', Science Advances, vol. 8, no. 6, abm1759 . https://doi.org/10.1126/sciadv.abm1759
Science Advances, 8(6). AMER ASSOC ADVANCEMENT SCIENCE
Science Advances, 8(6), 1-21
Science Advances, 8, 1-21
Science advances, 8(6):abm1759. American Association for the Advancement of Science
Kissel, T, Ge, C, Hafkenscheid, L, Kwekkeboom, J C, Slot, L M, Cavallari, M, He, Y, van Schie, K A, Vergroesen, R D, Kampstra, A S B, Reijm, S, Stoeken-Rijsbergen, G, Koeleman, C, Voortman, L M, Heitman, L H, Xu, B, Pruijn, G J M, Wuhrer, M, Rispens, T, Huizinga, T W J, Scherer, H U, Reth, M, Holmdahl, R & Toes, R E M 2022, ' Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation ', Science Advances, vol. 8, no. 6, abm1759 . https://doi.org/10.1126/sciadv.abm1759
Science Advances, 8(6). AMER ASSOC ADVANCEMENT SCIENCE
Science Advances, 8(6), 1-21
The hallmark autoantibodies in rheumatoid arthritis are characterized by variable domain glycans (VDGs). Their abundant occurrence results from the selective introduction of N-linked glycosylation sites during somatic hypermutation, and their presenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0208285deb500549af186c437aedd773
https://repository.ubn.ru.nl/handle/2066/248660
https://repository.ubn.ru.nl/handle/2066/248660
Autor:
M. Reth, E W N Levarht, Hans Scherer, J.C. Kwekkeboom, J. W. Drijfhout, Holger Bang, Sanne Reijm, Gerrie Stoeken-Rijsbergen, Arieke S. B. Kampstra, George M.C. Janssen, P.A. van Veelen, Marco Cavallari, Corrie M. Wortel, Rem Toes, Twj Huizinga, Theresa Kissel, Rochelle D Vergroesen, Kimberly M. Bonger, Linda M. Slot
Publikováno v:
Annals of the rheumatic diseases, 79(4):216499, 472-480. BMJ Publishing Group
Annals of the Rheumatic Diseases, 79, 472-480
Annals of the Rheumatic Diseases, 79, 4, pp. 472-480
Annals of the Rheumatic Diseases, 79(4), 472-480. BMJ PUBLISHING GROUP
Annals of the rheumatic disease
Annals of the Rheumatic Diseases, 79, 472-480
Annals of the Rheumatic Diseases, 79, 4, pp. 472-480
Annals of the Rheumatic Diseases, 79(4), 472-480. BMJ PUBLISHING GROUP
Annals of the rheumatic disease
ObjectiveAutoantibodies against antigens carrying distinct post-translational modifications (PTMs), such as citrulline, homocitrulline or acetyllysine, are hallmarks of rheumatoid arthritis (RA). The relation between these anti-modified protein antib
Autor:
Paul W. H. I. Parren, Marvyn T. Koning, Cornelis A.M. van Bergen, Hendrik Veelken, Rochelle D Vergroesen, Szymon M. Kielbasa, Ignis J. M. Trollmann, Rik Rademaker, René E. M. Toes, Esther M. Vletter, Hans Scherer
Publikováno v:
European Journal of Immunology, 50(12), 2099-2101. WILEY
European Journal of Immunology
European Journal of Immunology
RAG complexes recognise (cryptic) RSS sites both in and outside immunoglobulin sites. Excision circles may be reinserted into V(D)J rearrangements as long templated insertions to diversify the adaptive immune repertoire. We show that such VDJ with te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcbb361f7f579fb52625475d67e59c5
https://hdl.handle.net/1887/3182537
https://hdl.handle.net/1887/3182537
Autor:
Marvyn T. Koning, Cornelis P. Tensen, Edwin Quinten, Maarten H. Vermeer, Hailiang Mei, Cornelis A.M. van Bergen, Willem H. Zoutman, Hendrik Veelken, Rochelle D Vergroesen, Szymon M. Kielbasa, Rein Willemze, Patty M. Jansen
Publikováno v:
Journal of Investigative Dermatology, 139(10), 2195-2203
Primary cutaneous follicle center lymphoma (PCFCL) is a rare mature B-cell lymphoma with an unknown etiology. PCFCL resembles follicular lymphoma (FL) by cytomorphologic and microarchitectural criteria. FL B cells are selected for N-linked glycosylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d918eb1ce836973e4bcc5f7b817c86c7
https://hdl.handle.net/1887/120368
https://hdl.handle.net/1887/120368
Autor:
Ellen Staudinger, Tom W J Huizinga, Linda M. Slot, Hugo J. van Dooren, Hans Scherer, Rochelle D Vergroesen, Ellen I. H. van der Voort, René E. M. Toes, Sanne Reijm, Priscilla F Kerkman
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0247847 (2021)
PLoS ONE, 16(3). PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 16, Iss 3, p e0247847 (2021)
PLoS ONE, 16(3). PUBLIC LIBRARY SCIENCE
Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting 1% of the world population. RA is associated with the presence of autoantibodies, of which anti-citrullinated protein antibodies (ACPA) are most prominent. ACPA are produced by citru
Autor:
R.E.M. Toes, Twj Huizinga, Linda M. Slot, F.S. van de Bovenkamp, Marvyn T. Koning, T. Rispens, Hans Scherer, Rochelle D Vergroesen
Publikováno v:
FRIDAY, 15 JUNE 2018.
Background Anti-citrullinated protein antibodies (ACPA) represent the most specific biomarker in Rheumatoid Arthritis (RA) and have been associated with RA pathogenesis. ACPA-IgG are heavily N-glycosylated in the variable domain. Recently, we showed
Autor:
Hans Scherer, Christine A Grooff, Rochelle D Vergroesen, Marvyn T. Koning, Hendrik Veelken, Lise Hafkenscheid, Ellen I. H. van der Voort, Tom W J Huizinga, Linda M. Slot, Theo Rispens, George Zervakis, René E. M. Toes
Publikováno v:
Annals of the rheumatic diseases, 77, 956-958. BMJ Publishing Group
Annals of the Rheumatic Diseases, 77(6), 955
Annals of the Rheumatic Diseases, 77(6), 955
The majority of patients with rheumatoid arthritis (RA) harbours IgG antibodies targeting citrullinated protein antigens (ACPA). Recently, we showed that >90% of ACPA-IgG in serum are glycosylated in the variable domain.1 N -linked glycosylation requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd04bc107c0cfed21c792a5442b5e04c
https://pure.amc.nl/en/publications/bcell-receptor-sequencing-of-anticitrullinated-protein-antibody-acpa-iggexpressing-b-cells-indicates-a-selective-advantage-for-the-introduction-of-nglycosylation-sites-during-somatic-hypermutation(8a88ed58-a7c4-4881-acd2-16fcf236fe10).html
https://pure.amc.nl/en/publications/bcell-receptor-sequencing-of-anticitrullinated-protein-antibody-acpa-iggexpressing-b-cells-indicates-a-selective-advantage-for-the-introduction-of-nglycosylation-sites-during-somatic-hypermutation(8a88ed58-a7c4-4881-acd2-16fcf236fe10).html
Autor:
Rochelle D, Vergroesen, Linda M, Slot, Lise, Hafkenscheid, Marvyn T, Koning, Hans U, Scherer, René E M, Toes
Publikováno v:
Annals of the rheumatic diseases. 77(10)