Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rochelle Cunningham"'
Autor:
Olga Kovbasnjuk, Nicholas A. Frost, Edward J. Weinman, Rochelle Cunningham, Boyoung Cha, Deborah Steplock, Mark Donowitz, Shirish Shenolikar, Thomas A. Blanpied
Publikováno v:
American Journal of Physiology-Renal Physiology. 297:F1560-F1565
Renal sodium-dependent phosphate transporter 2a (Npt2a) binds to a number of PDZ adaptor proteins including sodium-hydrogen exchanger regulatory factor-1 (NHERF-1), which regulates its retention in the apical membrane of renal proximal tubule cells a
Autor:
Shirish Shenolikar, Rochelle Cunningham, Edward J. Weinman, Deborah Steplock, Rajatsubhra Biswas, Marc F. Brazie
Publikováno v:
American Journal of Physiology-Renal Physiology. 296:F355-F361
The present experiments were designed to detail factors regulating phosphate transport in cultured mouse proximal tubule cells by determining the response to parathyroid hormone (PTH), dopamine, and second messenger agonists and inhibitors. Both PTH
Autor:
Henry B.P.M. Dijkman, Boris M. Hogema, Rakhilya Murtazina, Shirish Shenolikar, James B. Wade, Hugo R. de Jonge, Eric Brown, Edward J. Weinman, Rochelle Cunningham, Johan van der Vlag, Rajat S. Biswas, Mark Donowitz, Ali Esmaili
Publikováno v:
American Journal of Physiology : Renal Physiology, 294, 4, pp. F1001-7
American Journal of Physiology : Renal Physiology, 294, F1001-7
American Journal of Physiology-Renal Physiology, 294(4), F1001-F1007. American Physiological Society
American Journal of Physiology : Renal Physiology, 294, F1001-7
American Journal of Physiology-Renal Physiology, 294(4), F1001-F1007. American Physiological Society
Urine electrolyte, mineral, and protein excretion in NHERF- 2 and NHERF-1 null mice. Am J Physiol Renal Physiol 294: F1001-F1007, 2008. First published February 6, 2008; doi:10.1152/ajprenal.00504.2007. -The adaptor proteins sodium/hydrogen exchanger
Autor:
James B. Wade, Fengying Wang, Rochelle Cunningham, Rajat S. Biswas, Deborah Steplock, Shirish Shenolikar, Hitoshi Endou, Naohiko Anzai, Srilatha Kanumuru, Xiaofei E, Edward J. Weinman, Marc F. Brazie
Publikováno v:
Journal of the American Society of Nephrology. 18:1419-1425
Sodium-hydrogen exchanger regulatory factor-1-deficient (NHERF-1(-/-)) mice demonstrate increases in the urinary excretion of phosphate, calcium, and uric acid associated with interstitial deposition of calcium in the papilla of the kidney. These stu
Autor:
Edward J. Weinman, Rajat S. Biswas, Deborah Steplock, Fengying Wang, Shirish Shenolikar, Xiaofei E, Rochelle Cunningham
Publikováno v:
American Journal of Physiology-Renal Physiology. 291:F896-F901
Sodium-dependent phosphate transport in NHERF-1−/−proximal tubule cells does not increase when grown in a low phosphate media and is resistant to the normal inhibitory effects of parathyroid hormone (PTH). The current experiments employ adenoviru
Autor:
Fengying Wang, Shirish Shenolikar, Rochelle Cunningham, Edward J. Weinman, Deborah Steplock, Nicholas Stoycheff, Viresh Mohanlal
Publikováno v:
American Journal of Physiology-Renal Physiology. 290:F838-F843
NHERF-1 binds numerous renal protein targets, including the proximal tubule transporters Na+/H+ exchanger 3 (NHE3) and Na+-phosphate cotransporter 2a (Npt2a). Young NHERF-1−/− male mice display defective targeting of Npt2a to apical membranes in
Publikováno v:
The Journal of Physiology. 567:27-32
Adaptor proteins containing PDZ interactive domains have been recently identified to regulate the trafficking and activity of ion transporters and channels in epithelial tissue. In the renal proximal tubule, three PDZ adaptor proteins, namely NHERF-1
Autor:
Rene C. Drachenberg, Emilio Ramos, Amr S. Khaled, Charles B. Cangro, David K. Klassen, Matthew R. Weir, Rawinder Wali, Jeffrey C. Fink, Rochelle Cunningham, Cinthia B. Drachenberg, Stephen T. Bartlett, John C. Papadimitriou
Publikováno v:
American Journal of Transplantation. 1:373-381
The morphological features of polyoma virus disease (PVDz) in 571 concurrent urine and biopsy samples from 413 patients are described. In 54 patients PV was found in both biopsy and urine samples. Histologically, PV presented as: (a) mild, viral cyto
Publikováno v:
Advances in chronic kidney disease. 18(2)
Renal phosphate transport is mediated by the abundance and activity of the sodium-dependent phosphate transporters, Npt2a, Npt2c, and PiT-2, present within the apical brush border membrane of the proximal tubule. Recent studies have demonstrated diff
Autor:
Rochelle Cunningham, Deborah Steplock, Rajatsubhra Biswas, Shirish Shenolikar, Edward J. Weinman
Publikováno v:
Urological research. 38(4)
Eukaryotic cells coordinate specific responses to hormones and growth factors by spatial and temporal organization of “signaling components.” Through the formation of multiprotein complexes, cells are able to generate “signaling components” t