Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Roc Reguant"'
Autor:
David Westergaard, Frederik Hytting Jørgensen, Jens Waaben, Alexander Wolfgang Jung, Mette Lademann, Thomas Folkmann Hansen, Jolien Cremers, Sisse Rye Ostrowski, Ole Birger Vesterager Pedersen, Danish Blood Donor Study Genomic Consortium, Roc Reguant, Isabella Friis Jørgensen, Tom Fitzgerald, Ewan Birney, Karina Banasik, Laust Mortensen, Søren Brunak
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Quantifying the contribution of genetics and environmental effects on disease initiation and progression, as well as the shared genetics of different diseases, is vital for the understanding of the disease etiology of multimorbidities. In th
Externí odkaz:
https://doaj.org/article/ede04cf429bf4046846437288035cd46
Autor:
Robert Dunne, Roc Reguant, Priya Ramarao-Milne, Piotr Szul, Letitia M.F. Sng, Mischa Lundberg, Natalie A. Twine, Denis C. Bauer
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4354-4360 (2023)
Random forests (RFs) are a widely used modelling tool capable of feature selection via a variable importance measure (VIM), however, a threshold is needed to control for false positives. In the absence of a good understanding of the characteristics o
Externí odkaz:
https://doaj.org/article/6ec28ccb8ba54d329a8d116c6276dab5
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Diabetic retinopathy (DR) is a leading cause of blindness and affects millions of people throughout the world. Early detection and timely checkups are key to reduce the risk of blindness. Automated grading of DR is a cost-effective way to en
Externí odkaz:
https://doaj.org/article/9fba7cc53af54f118f3f3f3889663b8b
Autor:
Troels Siggaard, Roc Reguant, Isabella F. Jørgensen, Amalie D. Haue, Mette Lademann, Alejandro Aguayo-Orozco, Jessica X. Hjaltelin, Anders Boeck Jensen, Karina Banasik, Søren Brunak
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The Danish health system has been collecting health-related data on the entire Danish population for years. Here the authors present the Danish Disease Trajectory Browser (DTB), which allows users to explore population-wide disease progression patter
Externí odkaz:
https://doaj.org/article/96ba881d42094af2a13b48b13192c77c
Autor:
Roc Reguant, Yevgeniy Antipin, Rob Sheridan, Christian Dallago, Drew Diamantoukos, Augustin Luna, Chris Sander, Nicholas Paul Gauthier
Publikováno v:
F1000Research, Vol 9 (2020)
AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and
Externí odkaz:
https://doaj.org/article/0b1f07fc91814428a93556b311023fdf
Autor:
Roc Reguant, Davide Placido, Benjamin Skov Kaas-Hansen, Søren Brunak, Hans-Christian Thorsen-Meyer
Frequent assessment of the severity of illness for hospitalized patients is essential in clinical settings to prevent outcomes such as in-hospital mortality and unplanned ICU admission. Classical severity scores have been developed typically using re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c1d7ac6700b9a684509b24f05a27cec
https://doi.org/10.1101/2022.08.30.22279381
https://doi.org/10.1101/2022.08.30.22279381
Autor:
Robert Dunne, Roc Reguant, Priya Ramarao-Milne, Piotr Szul, Letitia Sng, Mischa Lundberg, Natalie A. Twine, Denis C. Bauer
BackgroundRandom Forests (RF) are a widely used modelling tool, enabling feature-selection via a variable importance measure. For this, a threshold is required that separates label-associated features from false positives. In the absence of a good un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::254434587ac50da256d588826efd8ae0
https://doi.org/10.1101/2022.04.06.487300
https://doi.org/10.1101/2022.04.06.487300
Autor:
Roc Reguant, Jessica X. Hjaltelin, Alejandro Aguayo-Orozco, Karina Banasik, Isabella Friis Jørgensen, Mette Lademann, Anders Boeck Jensen, Søren Brunak, Amalie Dahl Haue, Troels Siggaard
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Siggaard, T, Reguant, R, Jørgensen, I F, Haue, A D, Lademann, M, Aguayo-Orozco, A, Hjaltelin, J X, Jensen, A B, Banasik, K & Brunak, S 2020, ' Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients ', Nature Communications, vol. 11, no. 1, 4952 . https://doi.org/10.1038/s41467-020-18682-4
Nature Communications
Siggaard, T, Reguant, R, Jørgensen, I F, Haue, A D, Lademann, M, Aguayo-Orozco, A, Hjaltelin, J X, Jensen, A B, Banasik, K & Brunak, S 2020, ' Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients ', Nature Communications, vol. 11, no. 1, 4952 . https://doi.org/10.1038/s41467-020-18682-4
We present the Danish Disease Trajectory Browser (DTB), a tool for exploring almost 25 years of data from the Danish National Patient Register. In the dataset comprising 7.2 million patients and 122 million admissions, users can identify diagnosis pa
Autor:
Roc Reguant, Rune Kjærsgaard Andersen, Isabella Friis Jørgensen, Gregor B.E. Jemec, Søren Brunak
Publikováno v:
JAMA Dermatol
IMPORTANCE: Hidradenitis suppurativa (HS) is a chronic skin disease characterized by recurrent inflamed nodular lesions and is associated with multiple comorbidities; previous studies have been of cross-sectional design, and the temporal association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1064f08d383a2870d001f1284506a8
https://europepmc.org/articles/PMC7240635/
https://europepmc.org/articles/PMC7240635/
Autor:
Rob Sheridan, Augustin Luna, Drew Diamantoukos, Chris Sander, Nicholas P. Gauthier, Yevgeniy Antipin, Roc Reguant, Christian Dallago
Publikováno v:
F1000Research
AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and