Maternal caloric restriction implemented during the preconceptional and pregnancy period alters hypothalamic and hippocampal endocannabinoid levels at birth and induces overweight and increased adiposity at adulthood in male rat offspring

Autor: MARÍA TERESA RAMÍREZ-LÓPEZ, Mariam Vazquez, Laura Bindila, Ermelinda Lomazzo, Clementine Hofmann, Noemi Blanco, Francisco Alen, MARIA ANTÓN, Juan Decara, Rocío Arco, Daniel Ouro, LAURA ORIO, JUAN SUAREZ, Beat Lutz, Raquel Gomez de Heras, FERNANDO RODRIGUEZ DE FONSECA

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 10 (2016)

Exposure to inadequate nutritional conditions in critical windows of development has been associated to disturbances on metabolism and behavior in the offspring later in life. The role of the endocannabinoid system, a known regulator of energy expend

Externí odkaz: https://doaj.org/article/6b49d00fc8794584855728b968b01db1

Abrupt cessation of reboxetine along alcohol deprivation results in alcohol intake escalation after reinstatement of drinking

Autor: Antonio Ballesta, Raquel Gómez de Heras, Evelyn Vadas, Fernando Rodríguez de Fonseca, Juan Decara, Antonia Serrano, Juan Suárez, Francisco Alén, Mayte Ramírez-López, Antonio Vargas, Laura Orio, Francisco Javier Pavón, Rocío Arco

Publikováno v: Addiction biologyREFERENCES. 26(3)

Major depression (MD) is a frequent comorbidity in alcohol use disorder (AUD) patients. Antidepressant prescription is often limited by poor clinical outcomes or unwanted side effects in comorbid AUD-MD patients. Recent studies suggest that abrupt ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6974ee8ba0ef52ae2eba94c2752d372
https://pubmed.ncbi.nlm.nih.gov/32815666

Bupropion, a possible antidepressant without negative effects on alcohol relapse

Autor: Francisco Alén, Mayte Ramírez-López, María Antón, Fernando Rodríguez de Fonseca, Antonia Serrano, Pablo Romero-Sanchiz, Raquel Gómez de Heras, Antonio Vargas, Laura Orio, Raquel Nogueira-Arjona, Juan Suárez, Francisco Javier Pavón, Rocío Arco, Antonio Ballesta

Publikováno v: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 29(6)

Rationale the role that antidepressants play on alcohol consumption is not well understood. Previous studies have reported that treatment with a Selective Serotonin Reuptake Inhibitor (SSRIs) increases alcohol consumption in an animal model of relaps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4569cc903b2c24fd0b09c9c0d68476
https://pubmed.ncbi.nlm.nih.gov/31064683

Long-Term Effects of Prenatal Exposure to Undernutrition on Cannabinoid Receptor-Related Behaviors: Sex and Tissue-Specific Alterations in the mRNA Expression of Cannabinoid Receptors and Lipid Metabolic Regulators

Autor: Fernando Rodríguez de Fonseca, Francisco Alén, Patricia Rivera, Mariam Vázquez, Rocío Arco, María Teresa Ramírez-López, Juan Decara, Rosario Noemi Blanco, Juan Suárez, Raquel Gómez de Heras

Publikováno v: Frontiers in Behavioral Neuroscience

Maternal malnutrition causes long-lasting alterations in feeding behavior and energy homeostasis in offspring. It is still unknown whether both, the endocannabinoid (eCB) machinery and the lipid metabolism are implicated in long-term adaptive respons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00caf101ce967bd5a39e56e997fa7234
https://www.frontiersin.org/articles/10.3389/fnbeh.2016.00241/pdf

Chronic IL-6 Administration Desensitizes IL-6 Response in Liver, Causes Hyperleptinemia and Aggravates Steatosis in Diet-Induced-Obese Mice

Autor: Antonia Serrano, Samir Badran, Dolores Bautista, Ana Luisa Gavito, Juan Suárez, Elena Baixeras, Juan Decara, Patricia Rivera, Fernando Rodríguez-de-Fonseca, Antonio Luis Cuesta, Francisco Javier Pavón, Rocío Arco

Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0157956 (2016)
Gavito, A L, Bautista, D, Suarez, J, Badran, S, Arco, R, Pavón, F J, Serrano, A, Rivera, P, Decara, J, Cuesta-Muñoz, A L, Rodríguez-de-Fonseca, F & Baixeras, E 2016, ' Chronic IL-6 Administration Desensitizes IL-6 Response in Liver, Causes Hyperleptinemia and Aggravates Steatosis in Diet-Induced-Obese Mice ', P L o S One, vol. 11, no. 6, e0157956 . https://doi.org/10.1371/journal.pone.0157956
PLoS ONE

Journal Article; High-fat diet-induced obesity (DIO) is associated with fatty liver and elevated IL-6 circulating levels. IL-6 administration in rodents has yielded contradictory results regarding its effects on steatosis progression. In some models

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae8d68727b8cd3ed6aa576b2bdeb8bb
http://europepmc.org/articles/PMC4917096?pdf=render