Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Robyn Washington Parks"'
Autor:
Maria Omsland, Cynthia Pise-Masison, Dai Fujikawa, Veronica Galli, Claudio Fenizia, Robyn Washington Parks, Bjørn Tore Gjertsen, Genoveffa Franchini, Vibeke Andresen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract The human T-cell leukemia virus type 1 (HTLV-1) is highly dependent on cell-to-cell interaction for transmission and productive infection. Cell-to-cell interactions through the virological synapse, biofilm-like structures and cellular condui
Externí odkaz:
https://doaj.org/article/e30af1feb123481aae23ed45050ec7e4
Autor:
Cynthia A Pise-Masison, Maria Fernanda de Castro-Amarante, Yoshimi Enose-Akahata, R Cody Buchmann, Claudio Fenizia, Robyn Washington Parks, Dustin Edwards, Martina Fiocchi, Luiz Carlos Alcantara, Izabela Bialuk, Jhanelle Graham, Jean-Claude Walser, Katherine McKinnon, Bernardo Galvão-Castro, Antoine Gessain, David Venzon, Steven Jacobson, Genoveffa Franchini
Publikováno v:
PLoS Pathogens, Vol 10, Iss 11, p e1004454 (2014)
HTLV-1 orf-I is linked to immune evasion, viral replication and persistence. Examining the orf-I sequence of 160 HTLV-1-infected individuals; we found polymorphism of orf-I that alters the relative amounts of p12 and its cleavage product p8. Three gr
Externí odkaz:
https://doaj.org/article/9e17af555d12428aa1e12ae0692fa84e
Autor:
Anna Gutowska, Sarkis Sarkis, Mohammad Arif Rahman, Katherine C. Goldfarbmuren, Ramona Moles, Massimiliano Bissa, Melvin Doster, Robyn Washington-Parks, Katherine McKinnon, Isabela Silva de Castro, Luca Schifanella, Genoveffa Franchini, Cynthia A. Pise-Masison
Publikováno v:
Pathogens, Vol 13, Iss 4, p 292 (2024)
The transient depletion of monocytes alone prior to exposure of macaques to HTLV-1 enhances both HTLV-1WT (wild type) and HTLV-1p12KO (Orf-1 knockout) infectivity, but seroconversion to either virus is not sustained over time, suggesting a progressiv
Externí odkaz:
https://doaj.org/article/244978497a084b2aa6b766b25236667b
Autor:
Anna Gutowska, Katherine McKinnon, Sarkis Sarkis, Melvin N. Doster, Massimiliano Bissa, Ramona Moles, James D. Stamos, Mohammad Arif Rahman, Robyn Washington-Parks, David Davis, Robert Yarchoan, Genoveffa Franchini, Cynthia A. Pise-Masison
Publikováno v:
Frontiers in medicine. 9
Human T cell leukemia virus type 1 (HTLV-1) persists in the host despite a vigorous immune response that includes cytotoxic T cells (CTL) and natural killer (NK) cells, suggesting the virus has developed effective mechanisms to counteract host immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b47070a90c5121b8476f4933dda3ca
https://pubmed.ncbi.nlm.nih.gov/35602479
https://pubmed.ncbi.nlm.nih.gov/35602479
Autor:
Ramona Moles, Sarkis Sarkis, Veronica Galli, Maria Omsland, Maria Artesi, Massimiliano Bissa, Katherine McKinnon, Sophia Brown, Vincent Hahaut, Robyn Washington-Parks, Joshua Welsh, David J. Venzon, Anna Gutowska, Melvin N. Doster, Matthew W. Breed, Kristin E. Killoran, Joshua Kramer, Jennifer Jones, Marcin Moniuszko, Anne Van den Broeke, Cynthia A. Pise-Masison, Genoveffa Franchini
Publikováno v:
PLoS pathogens. 18(4)
We investigated the impact of monocytes, NK cells, and CD8+ T-cells in primary HTLV-1 infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type (HTLV-1WT) or to the HTLV-1p12KO mutant unable to infect replete animals due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f7c1aeb961669a46dc52fd90b58580
https://pubmed.ncbi.nlm.nih.gov/35377924
https://pubmed.ncbi.nlm.nih.gov/35377924
Autor:
Josh Kramer, Xiaoying Shen, Karin Loré, Melvin N. Doster, Sanjay Phogat, David C. Montefiori, Monica Vaccari, David Venzon, Hung V. Trinh, Luca Schifanella, Dallas R. Brown, Frank Liang, Mangala Rao, Ranajit Pal, Michelle Metrinko, Georgia D. Tomaras, Matthew Breed, Giacomo Gorini, Massimiliano Bissa, Susan W. Barnett, Veronica Galli, Galit Alter, William Magnanelli, Genoveffa Franchini, Ruth M. Ruprecht, Namal P.M. Liyanage, Celia C. LaBranche, Robyn Washington-Parks
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008121 (2019)
PLoS Pathogens, Vol 16, Iss 4, p e1008531 (2020)
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 4, p e1008531 (2020)
PLoS Pathogens
The ALVAC-HIV clade B/AE and equivalent SIV-based/gp120 + Alum vaccines successfully decreased the risk of virus acquisition in humans and macaques. Here, we tested the efficacy of HIV clade B/C ALVAC/gp120 vaccine candidates + MF59 or different dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c4859929514a6d7ae3c330ff895349
https://doaj.org/article/ddf108f6beda493a8ef6fa3116999955
https://doaj.org/article/ddf108f6beda493a8ef6fa3116999955
Autor:
Maria Fernanda de Castro-Amarante, Maria Omsland, Giovanna S Brunetto, Katherine McKinnon, Breanna Caruso, Robyn Washington Parks, Raya Massoud, Genoveffa Franchini, Steven Jacobson, Veronica Galli, Vibeke Andresen, Cynthia A. Pise-Masison, David Venzon
Publikováno v:
Journal of Virology. 90:2195-2207
Because the viral DNA burden correlates with disease development, we investigated the contribution of monocyte subsets (classical, intermediate, and nonclassical monocytes) to the total viral burden in 22 human T cell leukemia virus type 1 (HTLV-1)-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e1df26978b0a60502010f767237d21
https://doi.org/10.1128/jvi.02735-15
https://doi.org/10.1128/jvi.02735-15
Autor:
Genoveffa Franchini, Melvin N. Doster, Sampa Santra, Rafick Pierre Sekaly, Slim Fourati, David C. Montefiori, Robyn Washington-Parks, Namal P.M. Liyanage, Richard Green, Robert E. Palermo, Michael Gale, Monica Vaccari, Mangala Rao, Deborah H. Fuller, Celia C. LaBranche, Giacomo Gorini, Hung V. Trinh, Mohammad Arif Rahman, Xiaoying Shen, David Venzon, Dallas R. Brown, Isabela Silva de Castro, Luca Schifanella, Michael B. Agy, Lynn Law, Ranajit Pal, Fredrik Barrenäs, Jean Chang, Veronica Galli, Massimiliano Bissa, Georgia D. Tomaras, Shari Gordon
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 3, p e1008377 (2020)
PLoS Pathogens, Vol 16, Iss 3, p e1008377 (2020)
The recombinant Canarypox ALVAC-HIV/gp120/alum vaccine regimen was the first to significantly decrease the risk of HIV acquisition in humans, with equal effectiveness in both males and females. Similarly, an equivalent SIV-based ALVAC vaccine regimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828c037a81c823bb9d41fecb2386bbc0
https://doi.org/10.1371/journal.ppat.1008377
https://doi.org/10.1371/journal.ppat.1008377
Autor:
Cynthia A. Pise-Masison, Dustin Edwards, Genoveffa Franchini, Robyn Washington Parks, Risaku Fukumoto, Luiz Carlos Junior Alcantara, Bernardo Galvão-Castro, Maria Fernanda de Castro-Amarante
Publikováno v:
Journal of Virology. 88:2319-2322
The orf-I gene of human T-cell leukemia type 1 (HTLV-1) encodes p8 and p12 and has a conserved cysteine at position 39. p8 and p12 form disulfide-linked dimers, and only the monomeric forms of p8 and p12 are palmitoylated. Mutation of cysteine 39 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af74631311baa2b133c76bb9f3ec56af
https://doi.org/10.1128/jvi.03444-13
https://doi.org/10.1128/jvi.03444-13
Autor:
Valentina Cecchinato, Jean-Michel Heraud, Gary Landucci, Stephen Whitney, Vibeke Andresen, Ruth H. Florese, Janos Nacsa, Izabela Bialuk, Thorsten Demberg, Marjorie Robert Guroff, Robyn Washington Parks, Donald N. Forthal, David Venzon, Shari N. Gordon, Genoveffa Franchini, Valerio W. Valeri, David C. Montefiori
Publikováno v:
Vaccine
Vaccine, Elsevier, 2011, 30 (1), pp.78-94. ⟨10.1016/j.vaccine.2011.10.040⟩
Vaccine, Elsevier, 2011, 30 (1), pp.78-94. ⟨10.1016/j.vaccine.2011.10.040⟩
International audience; The role of antibodies directed against the hyper variable envelope region V1 of human immunode-ficiency virus type 1 (HIV-1), has not been thoroughly studied. We show that a vaccine able to elicit strain-specific non-neutrali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90877bb81f0c5465649c2d6e2a8789b4
https://doi.org/10.1016/j.vaccine.2011.10.040
https://doi.org/10.1016/j.vaccine.2011.10.040