Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Robyn S, Klein"'
Autor:
Matthew D. Cain, N. Rubin Klein, Xiaoping Jiang, Hamid Salimi, Qingping Wu, Mark J. Miller, William B. Klimstra, Robyn S. Klein
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Venezuelan Equine Encephalitis virus (VEEV) may enter the central nervous system (CNS) within olfactory sensory neurons (OSN) that originate in the nasal cavity after intranasal exposure. While it is known that VEEV has evolved se
Externí odkaz:
https://doaj.org/article/05a07a3010704277b2efd1dcf91ec07d
Autor:
Artem Arutyunov, Violeta Durán-Laforet, Shenjian Ai, Loris Ferrari, Robert Murphy, Dorothy P. Schafer, Robyn S. Klein
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 808 (2024)
Microglia, the resident macrophages of the central nervous system, exhibit altered gene expression in response to various neurological conditions. This study investigates the relationship between West Nile Virus infection and microglial senescence, f
Externí odkaz:
https://doaj.org/article/f3f5f49756aa49bab2010450111a43fe
Autor:
Natasha M. Kafai, Hana Janova, Matthew D. Cain, Yael Alippe, Stefanie Muraro, Alan Sariol, Michelle Elam-Noll, Robyn S. Klein, Michael S. Diamond
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112946- (2023)
Summary: Venezuelan equine encephalitis virus (VEEV) is an encephalitic alphavirus responsible for epidemics of neurological disease across the Americas. Low-density lipoprotein receptor class A domain-containing 3 (LDLRAD3) is a recently reported en
Externí odkaz:
https://doaj.org/article/128a62baae2949b18c6c14e4e103cc19
Autor:
Sarah F. Rosen, Allison L. Soung, Wei Yang, Shenjian Ai, Marlene Kanmogne, Veronica A. Davé, Maxim Artyomov, Jeffrey A. Magee, Robyn S. Klein
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-20 (2022)
Abstract Background Emerging RNA viruses that target the central nervous system (CNS) lead to cognitive sequelae in survivors. Studies in humans and mice infected with West Nile virus (WNV), a re-emerging RNA virus associated with learning and memory
Externí odkaz:
https://doaj.org/article/b19782874e6d4d1aaba5a5d169da01ed
Autor:
Heather E. Whitson, Carol Colton, Joseph El Khoury, David Gate, Alison Goate, Michael T. Heneka, Rima Kaddurah-Daouk, Robyn S. Klein, Mari L. Shinohara, Sangram Sisodia, Serena S. Spudich, Beth Stevens, Rudolph Tanzi, Jenny P. Ting, Gwenn Garden, Alison Aiello, Ornit Chiba-Falek, Joseph Heitman, Kim G. Johnson, Micah Luftig, Ashley Moseman, Jonathan Rawls, Ronald Swanstrom, Niccolo Terrando
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 22, Iss , Pp 100462- (2022)
Neuroinflammation has been recognized as a component of Alzheimer's Disease (AD) pathology since the original descriptions by Alois Alzheimer and a role for infections in AD pathogenesis has long been hypothesized. More recently, this hypothesis has
Externí odkaz:
https://doaj.org/article/122264f3ba1c453b82785df1ba723c52
Autor:
Abigail Vanderheiden, Jeronay Thomas, Allison L. Soung, Meredith E. Davis-Gardner, Katharine Floyd, Fengzhi Jin, David A. Cowan, Kathryn Pellegrini, Adrian Creanga, Amarendra Pegu, Alexandrine Derrien-Colemyn, Pei-Yong Shi, Arash Grakoui, Robyn S. Klein, Steven E. Bosinger, Jacob E. Kohlmeier, Vineet D. Menachery, Mehul S. Suthar
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
Externí odkaz:
https://doaj.org/article/12d5b5bafec94e74979569fbd9832892
Autor:
Joshua B. Rubin, Joseph S. Lagas, Lauren Broestl, Jasmin Sponagel, Nathan Rockwell, Gina Rhee, Sarah F. Rosen, Si Chen, Robyn S. Klein, Princess Imoukhuede, Jingqin Luo
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-29 (2020)
Abstract We now know that cancer is many different diseases, with great variation even within a single histological subtype. With the current emphasis on developing personalized approaches to cancer treatment, it is astonishing that we have not yet s
Externí odkaz:
https://doaj.org/article/d1b971deab4047cd9d3542e6cd12a617
Autor:
Robyn S. Klein
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Many mosquito-borne viruses (arboviruses) are endemic in Africa, contributing to systemic and neurological infections in various geographical locations on the continent. While most arboviral infections do not lead to neuroinvasive diseases of the cen
Externí odkaz:
https://doaj.org/article/fd258b1efc9e42348d810f325d1e3b84
Autor:
Abigail Vanderheiden, Jeronay Thomas, Allison L. Soung, Meredith E. Davis-Gardner, Katharine Floyd, Fengzhi Jin, David A. Cowan, Kathryn Pellegrini, Adrian Creanga, Amarendra Pegu, Alexandrine Derrien-Colemyn, Pei-Yong Shi, Arash Grakoui, Robyn S. Klein, Steven E. Bosinger, Jacob E. Kohlmeier, Vineet D. Menachery, Mehul S. Suthar
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a historic pandemic of respiratory disease (coronavirus disease 2019 [COVID-19]), and current evidence suggests that severe disease is associated with dysregulated immun
Externí odkaz:
https://doaj.org/article/338d7fe83d2f443ab2dd478f383e3881
Autor:
Sindhu Manivasagam, Robyn S. Klein
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Type III interferons (IFNs) or the lambda IFNs (IFNLs or IFN-λs) are antimicrobial cytokines that play key roles in immune host defense at endothelial and epithelial barriers. IFNLs signal via their heterodimeric receptor, comprised of two subunits,
Externí odkaz:
https://doaj.org/article/30974b42fe614b708565ecd69cff0406