Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Robyn Rosenfeld"'
Autor:
Andrea Jurisicova, Yonit Tsatskis, Rod Bremner, John R. B. Perry, Kyunga Kim, Brian Ciruna, Daniel Potter, Dorothea Godt, Wade H. Dunham, Yu Sun, Michael I. Robson, Shu Wu, Robyn Rosenfeld, Julie A. Brill, Karen Krchma, Tim Schedl, Anne-Claude Gingras, Joel Pearson, Curtis W. Boswell, Helen McNeill, Kyunghee Choi, Laurence Pelletier, Didier Hodzic, Jin Meng, Lacramioara Fabian, Yi Qu, Ariz Mohammad, Eric C. Schirmer, João Gonçalves, Jun Wu, Xian Wang
Publikováno v:
Science Advances
Tsatskis, Y, Rosenfeld, R, Pearson, J D, Boswell, C, Qu, Y, Kim, K, Fabian, L, Mohammed, A, Wang, X, Robson, M, Krchma, K, Wu, J, Gonçalves, J, Hodzic, D, Wu, S, Potter, D, Pelletier, L, Dunham, W H, Gingras, A-C, Sun, Y, Meng, J, Godt, D, Schedl, T, Ciruna, B, Choi, K, Perry, J R B, Bremner, R, Schirmer, E C, Brill, J A, Jurisicova, A & McNeill, H 2020, ' The NEMP family supports metazoan fertility and nuclear envelope stiffness ', Science Advances, vol. 6, eabb4591 . https://doi.org/10.1126/sciadv.abb4591
Tsatskis, Y, Rosenfeld, R, Pearson, J D, Boswell, C, Qu, Y, Kim, K, Fabian, L, Mohammed, A, Wang, X, Robson, M, Krchma, K, Wu, J, Gonçalves, J, Hodzic, D, Wu, S, Potter, D, Pelletier, L, Dunham, W H, Gingras, A-C, Sun, Y, Meng, J, Godt, D, Schedl, T, Ciruna, B, Choi, K, Perry, J R B, Bremner, R, Schirmer, E C, Brill, J A, Jurisicova, A & McNeill, H 2020, ' The NEMP family supports metazoan fertility and nuclear envelope stiffness ', Science Advances, vol. 6, eabb4591 . https://doi.org/10.1126/sciadv.abb4591
Loss of Nemp leads to softening of the germline nuclear envelope and loss of fertility.
Human genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in NEMP1 (nuclear envelope membrane protein 1) with early menopause;
Human genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in NEMP1 (nuclear envelope membrane protein 1) with early menopause;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::526b5f096f3c9b8dfa6e5d0b8a6b78dd
Publikováno v:
Mechanisms of Development. 126(8-9):605-610
The Drosophila HOX transcription factor, Sex combs reduced (SCR), is required for determining labial and the first thoracic segmental identity. A Protein Phosphatase 2A holoenzyme assembled with the PP2A-B′ regulatory subunit is proposed to specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacf81b20e38baedbd891685d9494dc9
Autor:
Nancy Amin, Ankush Garg, Robyn Rosenfeld, Caroline Badouel, Laura Gardano, Thierry Le Bihan, Helen McNeill
Publikováno v:
Developmental Cell. 16(3):411-420
SummaryThe Hippo kinase pathway plays a central role in growth regulation and tumor suppression from flies to man. The Hippo/Mst kinase phosphorylates and activates the NDR family kinase Warts/Lats, which phosphorylates and inhibits the transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a661a2c4a5715f8741333210b8207e7