Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Robyn P. Araujo"'
Publikováno v:
Royal Society Open Science, Vol 11, Iss 10 (2024)
Tight homeostatic control of cholesterol concentration within the complex tissue microenvironment of the retina is the hallmark of a healthy eye. By contrast, dysregulation of biochemical mechanisms governing retinal cholesterol homeostasis likely co
Externí odkaz:
https://doaj.org/article/9cb18b3b05c6455fa9e14b65e09f4cd8
Autor:
Jessica A. Roman, Michael Y. Girgis, Rocìo S. Prisby, Robyn P. Araujo, Paul Russo, Esra Oktay, Alessandra Luchini, Lance A. Liotta, Remi Veneziano, Amanda Haymond
Publikováno v:
Advanced NanoBiomed Research, Vol 4, Iss 7, Pp n/a-n/a (2024)
Despite success in the treatment of some blood cancers and melanoma, positive response to immunotherapies remains disappointingly low in the treatment of solid tumors. The context of the molecular crosstalk within the tumor microenvironment can resul
Externí odkaz:
https://doaj.org/article/6aed4962c00144eaa3fb102bb2d0c299
Autor:
Robyn P. Araujo, Lance A. Liotta
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract At the molecular level, the evolution of life is driven by the generation and diversification of adaptation mechanisms. A universal description of adaptation-capable chemical reaction network (CRN) structures has remained elusive until now,
Externí odkaz:
https://doaj.org/article/f91b100a05bd4bc6bc99e856853b127d
Autor:
Robyn P. Araujo, Lance A. Liotta
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/15d98b9c8a094077b5f6c54e9fcfd92f
Autor:
Ronél Scheepers, Robyn P. Araujo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Although cholesterol is essential for cellular viability and proliferation, it is highly toxic in excess. The concentration of cellular cholesterol must therefore be maintained within tight tolerances, and is thought to be subject to a stringent form
Externí odkaz:
https://doaj.org/article/1492342e420b4975ae7e0b2d847f7eeb
Autor:
Marissa Howard, James Erickson, Zachary Cuba, Shawn Kim, Weidong Zhou, Purva Gade, Rachel Carter, Kelsey Mitchell, Heather Branscome, Daivik Siddhi, Fatimah Alanazi, Yuriy Kim, Robyn P. Araujo, Amanda Haymond, Alessandra Luchini, Fatah Kashanchi, Lance A. Liotta
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 7, Pp n/a-n/a (2022)
Abstract We characterized the in vivo interstitial fluid (IF) content of extracellular vesicles (EVs) using the GFP‐4T1 syngeneic murine cancer model to study EVs in‐transit to the draining lymph node. GFP labelling confirmed the IF EV tumour cel
Externí odkaz:
https://doaj.org/article/e005fbbe87c040998042b508de07e1d0
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
A model needs to make verifiable predictions to have any scientific value. In opinion dynamics, the study of how individuals exchange opinions with one another, there are many theoretical models which attempt to model opinion exchange, one of which i
Externí odkaz:
https://doaj.org/article/1a84e339a206472eba0b97280e0b338c
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
In opinion dynamics, as in general usage, polarisation is subjective. To understand polarisation, we need to develop more precise methods to measure the agreement in society. This paper presents four mathematical measures of polarisation derived from
Externí odkaz:
https://doaj.org/article/1f1c945843cb496c9fa385a621c7b70c
Autor:
Robyn P. Araujo, Lance A. Liotta
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Robust perfect adaptation (RPA), the ability of a system to return to its pre-stimulus state in the presence of a new signal, enables organisms to respond to further changes in stimuli. Here, the authors identify the modular structure of the full set
Externí odkaz:
https://doaj.org/article/2b66dcdf8fc54ecab0e4b89aab8403ee
Autor:
Lance A. Liotta, Lee J. Helman, Kartik Krishnan, Maria Tsokos, Stephen Qualman, Donald J. Johann, Gabriel S. Eichler, Xiaolin Wan, Choh Yeung, Brieanne Midura, Robyn P. Araujo, Virginia Espina, Emanuel F. Petricoin
Mapping of protein signaling networks within tumors can identify new targets for therapy and provide a means to stratify patients for individualized therapy. Despite advances in combination chemotherapy, the overall survival for childhood rhabdomyosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7763f55c06c450d6ff81c39545b59da
https://doi.org/10.1158/0008-5472.c.6495654
https://doi.org/10.1158/0008-5472.c.6495654