Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Robyn M. Murphy"'
Autor:
Erin M. Lloyd, Rachael C. Crew, Vanessa R. Haynes, Robert B. White, Peter J. Mark, Connie Jackaman, John M. Papadimitriou, Gavin J. Pinniger, Robyn M. Murphy, Matthew J. Watt, Miranda D. Grounds
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Background Dysferlinopathies are a clinically heterogeneous group of muscular dystrophies caused by gene mutations resulting in deficiency of the membrane-associated protein dysferlin. They manifest post-growth and are characterised by muscl
Externí odkaz:
https://doaj.org/article/0c448a32f56c4df5ba7907509802fbfa
Autor:
Tanya R. Cully, Robyn M. Murphy, Llion Roberts, Truls Raastad, Robert G. Fassett, Jeff S. Coombes, Izzy Jayasinghe, Bradley S. Launikonis
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Abstract High-force eccentric exercise results in sustained increases in cytoplasmic Ca2+ levels ([Ca2+]cyto), which can cause damage to the muscle. Here we report that a heavy-load strength training bout greatly alters the structure of the membrane
Externí odkaz:
https://doaj.org/article/ac5dc5c88c904369b9a94eb7648f2c36
Publikováno v:
Sports, Vol 6, Iss 4, p 109 (2018)
An increasing number of studies have shown supplementation with the amino acid taurine to have promise in ameliorating dystrophic symptoms in the mdx mouse model of Duchenne Muscular Dystrophy (DMD). Here we build on this limited body of work by inve
Externí odkaz:
https://doaj.org/article/f538e18ae10645668fe04d2ada416ad0
Autor:
Crystal Seng, Luke Pearce, Aldo Meizoso-Huesca, Daniel P. Singh, Robyn M. Murphy, Cedric R. Lamboley, Bradley S. Launikonis
Publikováno v:
American Journal of Physiology-Cell Physiology. 323:C1285-C1289
Ca2+ is an integral component of the functional and developmental regulation of the mitochondria. In skeletal muscle, Ca2+ is reported to modulate the rate of ATP resynthesis, regulate the expression of peroxisome proliferator-activated receptor-gamm
Autor:
María G. Morales-Scholz, Stefan G. Wette, Jayden R. Stokie, Bianca T. Tepper, Courtney Swinton, David L. Hamilton, Karen M. Dwyer, Robyn M. Murphy, Kirsten F. Howlett, Christopher S. Shaw
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 323:E242-E253
The aim of the present study was to investigate the fiber type-specific abundance of autophagy-related proteins after an overnight fast and following ingestion of a mixed meal in human skeletal muscle. Twelve overweight, healthy young male volunteers
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9405
Calpain-3 (CAPN3) is a muscle-specific member of the calpain family of Ca2+-dependent proteases. It has been reported that CAPN3 can also be autolytically activated by Na+ ions in the absence of Ca2+, although this was only shown under non-physiologi
Autor:
Daniel P. Singh, Luke Pearce, Rocky H. Choi, Aldo Meizoso-Huesca, Stefan G. Wette, John W. Scott, Cedric R. Lamboley, Robyn M. Murphy, Bradley S. Launikonis
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Resting skeletal muscle generates heat for endothermy in mammals but not amphibians, while both use the same Ca 2+ -handling proteins and membrane structures to conduct excitation–contraction coupling apart from having different ryanodine receptor
Autor:
Andrew Garnham, Barnaby P. Frankish, Robyn M. Murphy, Mark Hargreaves, David Stapleton, Marcelo Flores-Opazo
Publikováno v:
Physiological Reports
Previous studies have demonstrated that exercise increases whole body and skeletal muscle insulin sensitivity that is linked with increased GLUT4 at the plasma membrane following insulin stimulation and associated with muscle glycogen depletion. To a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e964c18967eb7d5f3171e38ddadcbc
Autor:
Robyn M. Murphy, Sean L. McGee, Mark Hargreaves, Marcelo Flores-Opazo, Eva Boland, Andrew Garnham
Publikováno v:
Physiological Reports
To examine the effect of acute and chronic exercise on adipose tissue GLUT4 expression, a total of 20 healthy, male subjects performed one of two studies. Ten subjects performed cycle ergometer exercise for 60 min at 73 ± 2% VO 2 peak and abdominal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951f7a3b16faca53448475e12f162bbf
Publikováno v:
PLOS ONE. 18:e0286286