Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Robyn M Sutherland"'
Autor:
Zhijun Jiao, Sammy Bedoui, Jamie L Brady, Anne Walter, Michael Chopin, Emma M Carrington, Robyn M Sutherland, Stephen L Nutt, Yuxia Zhang, Hyun-Ja Ko, Li Wu, Andrew M Lew, Yifan Zhan
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91126 (2014)
Migratory CD103+ and lymphoid-resident CD8+ dendritic cells (DCs) share many attributes, such as dependence on the same transcription factors, cross-presenting ability and expression of certain surface molecules, such that it has been proposed they b
Externí odkaz:
https://doaj.org/article/aabaed0501c94059a10dc4bff8f8bac0
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48977 (2012)
Pancreas stem cells are a potential source of insulin-producing β cells for the therapy of diabetes. In adult tissues the 'side population' (SP) of cells that effluxes the DNA binding dye Hoechst 33342 through ATP-binding cassette transporters has s
Externí odkaz:
https://doaj.org/article/e62cd71d4c8a4a65b42ec1df942cf25f
Autor:
Robyn M. Sutherland, Sarah L. Londrigan, Jamie L. Brady, Emma M. Carrington, Julia M. Marchingo, Susanne Heinzel, Philip D. Hodgkin, Kate L. Graham, Thomas W. Kay, Yifan Zhan, Andrew M. Lew
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Professional antigen presenting cells (APC) are the major activator of T cells that then hone to sites of inflammation. Using islet cell grafts, here the authors show that parenchymal cells can present antigen to activate CD8+T cells at inflammatory
Externí odkaz:
https://doaj.org/article/ddf258470896415aaf2e07fd3e6bba40
Autor:
Jai Rautela, Peter E. Czabotar, Tobias Kratina, Christine R. Keenan, Yifan Zhan, Huon L. Wong, Nicholas D. Huntington, Manuela S Hancock, Christine A White, Emma M. Carrington, Ahmad Wardak, Vanessa L. Bryant, Wesley Wong, Rhys S. Allan, Guillaume Lessene, Yuyan Yang, Damian B D'Silva, Robyn L Schenk, Andrew M. Lew, Jacinta Hansen, Nadia Iannarella, Marco J Herold, Cynthia Louis, Robyn M. Sutherland, Ian P. Wicks, Duong Nhu
Publikováno v:
Blood Adv
Neutrophils help to clear pathogens and cellular debris, but can also cause collateral damage within inflamed tissues. Prolonged neutrophil residency within an inflammatory niche can exacerbate tissue pathology. Using both genetic and pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdaa032d6d3dbd2b6325707daeeec77
https://europepmc.org/articles/PMC8238482/
https://europepmc.org/articles/PMC8238482/
Autor:
Ingela B Vikstrom, Suzanne Cory, Philippe Bouillet, Natasha S Anstee, Nicholas D. Huntington, Andreas Strasser, Emma M. Carrington, David C.S. Huang, Yifan Zhan, Jian-Guo Zhang, Jamie L. Brady, David M. Tarlinton, Marco J Herold, Andrew M. Lew, Robyn M. Sutherland, Robyn L Schenk, Rebecca B. Delconte, David J. Segal
Publikováno v:
Cell Death & Differentiation. 24:878-888
Survival of various immune cell populations has been proposed to preferentially rely on a particular anti-apoptotic BCL-2 family member, for example, naive T cells require BCL-2, while regulatory T cells require MCL-1. Here we examined the survival r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e94b63628169635bea156c7a83fa0b
https://doi.org/10.1038/cdd.2017.30
https://doi.org/10.1038/cdd.2017.30
Publikováno v:
Immunology & Cell Biology. 95:244-251
Dendritic cells (DCs) are professional antigen-presenting cells that consist of functionally and phenotypically heterogeneous populations. Monocyte-derived DCs (moDCs) are a DC subset that have been attracting increasing interest owing to their poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6119073f9d5af27a5c5362a01f05c6a0
https://doi.org/10.1038/icb.2016.104
https://doi.org/10.1038/icb.2016.104
Autor:
Nicholas D. Huntington, Rebecca B. Delconte, Robyn M. Sutherland, Yifan Zhan, David M. Tarlinton, Andrew M. Lew, Kevin V. Chow
Publikováno v:
The Journal of Immunology. 197:2000-2008
Although the mechanisms governing the innate recognition of pathogen-associated molecular patterns have been well defined, how allogeneic cellular stimuli evoke innate responses remains less so. In this article, we report that upon i.v. transfer (to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b3a73d95795a1e9f5208c338d7e713
https://doi.org/10.4049/jimmunol.1600181
https://doi.org/10.4049/jimmunol.1600181
Publikováno v:
The Journal of Immunology. 196:624-636
Monocyte-derived dendritic cells (moDCs) dramatically increase in numbers upon infection and inflammation; accordingly, we found that this also occurs during allogeneic responses. Despite their prominence, how emergent moDCs and resident conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a452810924900e53a75b732312753bf6
https://doi.org/10.4049/jimmunol.1501202
https://doi.org/10.4049/jimmunol.1501202
Autor:
Erinna F. Lee, W. Douglas Fairlie, David M. Tarlinton, Stephanie Grabow, Eleonora Ottina, Philippe Bouillet, Priscilla Soo, Cody C. Allison, Andreas Strasser, Yifan Zhan, Ingela B Vikstrom, Andrew M. Lew, Jamie L. Brady, Marco J Herold, David Vremec, David C.S. Huang, Jian-Guo Zhang, Emma M. Carrington, Marc Pellegrini, Robyn M. Sutherland
Publikováno v:
Proceedings of the National Academy of Sciences. 112:4044-4049
Dendritic cells (DCs) are heterogeneous, comprising subsets with functional specializations that play distinct roles in immunity as well as immunopathology. We investigated the molecular control of cell survival of two main DC subsets: plasmacytoid D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23670bd1a2fb03d9d4f63ee4532d5cec
https://doi.org/10.1073/pnas.1417620112
https://doi.org/10.1073/pnas.1417620112
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Islet transplantation can cure type 1 diabetes but is limited by lack of donor organs and early graft dysfunction, such that many patients require multiple transplants to achieve insulin independence. Monocyte-derived dendritic cells (moDCs) arise du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23013898a024258d8de1fbe6249db9f4
https://europepmc.org/articles/PMC5657768/
https://europepmc.org/articles/PMC5657768/