Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Robyn J, Eisert"'
Autor:
Katherine J. Susa, Gary A. Bradshaw, Robyn J. Eisert, Charlotte M. Schilling, Marian Kalocsay, Stephen C. Blacklow, Andrew C. Kruse
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114332- (2024)
Summary: The B cell receptor (BCR) signals together with a multi-component co-receptor complex to initiate B cell activation in response to antigen binding. Here, we take advantage of peroxidase-catalyzed proximity labeling combined with quantitative
Externí odkaz:
https://doaj.org/article/1216f0b2527b47618886cbc540d72911
Autor:
Marian Kalocsay, Matthew J. Berberich, Robert A. Everley, Maulik K. Nariya, Mirra Chung, Benjamin Gaudio, Chiara Victor, Gary A. Bradshaw, Robyn J. Eisert, Marc Hafner, Peter K. Sorger, Caitlin E. Mills, Kartik Subramanian
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-9 (2023)
Abstract We performed quantitative proteomics on 60 human-derived breast cancer cell line models to a depth of ~13,000 proteins. The resulting high-throughput datasets were assessed for quality and reproducibility. We used the datasets to identify an
Externí odkaz:
https://doaj.org/article/d36f69bd2a254d5687bc8e7f98e95fc1
Autor:
Arianne Papa, Sergey I. Zakharov, Alexander N. Katchman, Jared S. Kushner, Bi-xing Chen, Lin Yang, Guoxia Liu, Alejandro Sanchez Jimenez, Robyn J. Eisert, Gary A. Bradshaw, Wen Dun, Shah R. Ali, Aaron Rodriques, Karen Zhou, Veli Topkara, Mu Yang, John P. Morrow, Emily J. Tsai, Arthur Karlin, Elaine Wan, Marian Kalocsay, Geoffrey S. Pitt, Henry M. Colecraft, Manu Ben-Johny, Steven O. Marx
Publikováno v:
Nature Cardiovascular Research. 1:1022-1038
Fight-or-flight responses involve β-adrenergic-induced increases in heart rate and contractile force. In the present study, we uncover the primary mechanism underlying the heart’s innate contractile reserve. We show that four protein kinase A (PKA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d29a7152c7195aa5159ea1ac39befef0
https://doi.org/10.1038/s44161-022-00157-y
https://doi.org/10.1038/s44161-022-00157-y
Autor:
Arianne, Papa, Sergey I, Zakharov, Alexander N, Katchman, Jared S, Kushner, Bi-Xing, Chen, Lin, Yang, Guoxia, Liu, Alejandro Sanchez, Jimenez, Robyn J, Eisert, Gary A, Bradshaw, Wen, Dun, Shah R, Ali, Aaron, Rodriques, Karen, Zhou, Veli, Topkara, Mu, Yang, John P, Morrow, Emily J, Tsai, Arthur, Karlin, Elaine, Wan, Marian, Kalocsay, Geoffrey S, Pitt, Henry M, Colecraft, Manu, Ben-Johny, Steven O, Marx
Publikováno v:
Nature cardiovascular research. 1(11)
Fight-or-flight responses involve β-adrenergic-induced increases in heart rate and contractile force. In the present study, we uncover the primary mechanism underlying the heart's innate contractile reserve. We show that four protein kinase A (PKA)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::098eb2ff6d51588c62d0ba69760229f2
https://pubmed.ncbi.nlm.nih.gov/36424916
https://pubmed.ncbi.nlm.nih.gov/36424916
Autor:
Katherine J. Susa, Gary A. Bradshaw, Robyn J. Eisert, Charlotte M. Schilling, Marian Kalocsay, Stephen C. Blacklow, Andrew C. Kruse
Publikováno v:
bioRxiv
The B cell receptor (BCR) signals together with a multi-component co-receptor complex to initiate B cell activation in response to antigen binding. This process underlies nearly every aspect of proper B cell function. Here, we take advantage of perox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5a064b846c12788cfc0066f0189f6a
https://doi.org/10.1101/2023.03.17.533227
https://doi.org/10.1101/2023.03.17.533227
Autor:
Alexandre P. Martin, Gary A. Bradshaw, Robyn J. Eisert, Emily D. Egan, Lena Tveriakhina, Julia M. Rogers, Andrew N. Dates, Gustavo Scanavachi, Jon C. Aster, Tom Kirchhausen, Marian Kalocsay, Stephen C. Blacklow
Notch signaling relies on ligand-induced proteolysis to liberate a nuclear effector that drives cell fate decisions. The location and timing of individual steps required for proteolysis and movement of Notch from membrane to nucleus, however, remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72eec61f8f702d2a049806bff5c2a4d9
https://doi.org/10.1101/2022.12.21.521435
https://doi.org/10.1101/2022.12.21.521435
Autor:
Jared S. Kushner, Guoxia Liu, Robyn J. Eisert, Gary A. Bradshaw, Geoffrey S. Pitt, J. Travis Hinson, Marian Kalocsay, Steven O. Marx
Publikováno v:
Circ Res
Rapidly changing and transient protein-protein interactions regulate dynamic cellular processes in the cardiovascular system. Traditional methods, including affinity purification and mass spectrometry, have revealed many macromolecular complexes in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7245fa1fdfa59e05fa18065a89ee20
https://europepmc.org/articles/PMC8852690/
https://europepmc.org/articles/PMC8852690/
Autor:
Marian Kalocsay, Zoltan Maliga, Ajit J. Nirmal, Robyn J. Eisert, Gary A. Bradshaw, Isaac H Solomon, Yu-An Chen, Roxanne J. Pelletier, Connor A. Jacobson, Julian Mintseris, Robert F. Padera, Amanda J. Martinot, Dan H. Barouch, Sandro Santagata, Peter K. Sorger
Normal tissue physiology and repair depends on communication with the immune system. Understanding this communication at the molecular level in intact tissue requires new methods. The consequences of SARS-CoV-2 infection, which can result in acute re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d415d4c86c19eb36c81cb97395a73fa
https://doi.org/10.1101/2020.10.14.339952
https://doi.org/10.1101/2020.10.14.339952
Autor:
Alissa J. Kamens, Joshua A. Kritzer, Robyn J. Eisert, Kaley M. Mientkiewicz, Charles R. Mace, Jenna A. Walz
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:1206-1211
Recycling of receptors from the endosomal recycling compartment to the plasma membrane is a critical cellular process, and recycling is particularly important for maintaining invasiveness in solid tumors. In this work, we continue our efforts to inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b098501152311dc9282220f0e51ac2b
https://doi.org/10.1016/j.bmc.2017.09.007
https://doi.org/10.1016/j.bmc.2017.09.007
Publikováno v:
Biochemistry. 54:2314-2322
Methylated lysine 9 on the histone 3 (H3) tail recruits heterochromatin protein 1 from Drosophila (dHP1) via its chromodomain and results in gene silencing. The dHP1 chromodomain binds H3 K9Me3 with an aromatic cage surrounding the trimethyllysine. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c67292fdfbd208f694151d433040b0
https://doi.org/10.1021/acs.biochem.5b00024
https://doi.org/10.1021/acs.biochem.5b00024