Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Robyn G. C. Macrae"'
Autor:
Thomas L. Williams, Robyn G. C. Macrae, Rhoda E. Kuc, Alastair J. H. Brown, Janet J. Maguire, Anthony P. Davenport
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionThe apelin receptor binds two distinct endogenous peptides, apelin and ELA, which act in an autocrine/paracrine manner to regulate the human cardiovascular system. As a class A GPCR, targeting the apelin receptor is an attractive therapeu
Externí odkaz:
https://doaj.org/article/bf7d26bd0e894f9489e39b0a341afeaa
Autor:
Thomas L. Williams, Gregory Strachan, Robyn G. C. Macrae, Rhoda E. Kuc, Duuamene Nyimanu, Anna L. Paterson, Sanjay Sinha, Janet J. Maguire, Anthony P. Davenport
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract ACE2 is a membrane protein that regulates the cardiovascular system. Additionally, ACE2 acts as a receptor for host cell infection by human coronaviruses, including SARS-CoV-2 that emerged as the cause of the on-going COVID-19 pandemic and h
Externí odkaz:
https://doaj.org/article/4c7d25172fb64bbb8805217fa8c59d59
Autor:
Thomas L. Williams, Maria T. Colzani, Robyn G. C. Macrae, Emma L. Robinson, Stuart Bloor, Edward J. D. Greenwood, Jun Ru Zhan, Gregory Strachan, Rhoda E. Kuc, Duuamene Nyimanu, Janet J. Maguire, Paul J. Lehner, Sanjay Sinha, Anthony P. Davenport
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Williams et al. confirm that human embryonic stem cell-derived cardiomyocytes express the protein machinery critical for SARS-CoV-2 infection and are susceptible to SARS-CoV-2 spike protein pseudotyped virus infection. They further use this platform
Externí odkaz:
https://doaj.org/article/38772e0bff5a4477befd0ea1c3205005