Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Robyn Emmins"'
Autor:
Thomas Jostock, Chris Campbell, Karin Anderson, Ren Liu, Yuan Zhu, Juhi Ojha, Zhimei Du, Rolf Koehler, Robyn Emmins, Howard Clarke, Louise Almond, Paul Wu, Christina S. Alves, John Thrift, Michael W. Laird, David E. Shaw, Taymar Hartman, Jennitte Stevens
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 74:264-274
The bioprocessing industry uses recombinant mammalian cell lines to generate therapeutic biologic drugs. To ensure consistent product quality of the therapeutic proteins, it is imperative to have a controlled production process. Regulatory agencies a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a669404104723d3fb09a0ccb5078f2
https://doi.org/10.5731/pdajpst.2018.009316
https://doi.org/10.5731/pdajpst.2018.009316
Autor:
Amie M. Lundquist, Duncan McVey, Zhimei Du, Jennifer Di-Carlo, Nan-Xin Qian, Matthew Reeser, Jared Spidel, Yuan Zhu, Sarah Amelia Milne, Tony Gill, Karin Anderson, John A. Follit, Michael W. Laird, Anke Mayer-Bartschmid, John Gill, Hervé Broly, Andrew J. Racher, Christian Bender, Jerry Carson, Alison Porter, Sampath R. Kumar, Qingxiang Wei, Robyn Emmins, David E. Shaw, Ankita Khatri, Frank Lee, Marilyne Failly, Ivan Carubelli, Kyle Zingaro, Christine Demaria, Christina S. Alves
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 72:438-450
Monoclonality of mammalian cell lines used for production of biologics is a regulatory expectation and one of the attributes assessed as part of a larger process to ensure consistent quality of the biologic. Historically, monoclonality has been demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f42f4cdb9204212a17ff3b925af7ffa
https://doi.org/10.5731/pdajpst.2018.008789
https://doi.org/10.5731/pdajpst.2018.008789
Publikováno v:
Molecular Microbiology. 106:304-318
Bacterial cell division involves the dynamic assembly of a diverse set of proteins that coordinate the invagination of the cell membrane and synthesis of cell wall material to create the new cell poles of the separated daughter cells. Penicillin-bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7efdcda4223d64f319a32a1fcb79f8c
https://doi.org/10.1111/mmi.13765
https://doi.org/10.1111/mmi.13765
Publikováno v:
Molecular Microbiology
Summary Bacterial cell division involves the dynamic assembly of a diverse set of proteins that coordinate the invagination of the cell membrane and synthesis of cell wall material to create the new cell poles of the separated daughter cells. Penicil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aef01184ca0ef42a4b4b4ef5a2a264e1
https://pubmed.ncbi.nlm.nih.gov/28792086
https://pubmed.ncbi.nlm.nih.gov/28792086
Autor:
Richard J. Lewis, Jon Marles-Wright, Nadja Heinz, Jeff Errington, Shu Ishikawa, Yoshikazu Kawai, Nhat Khai Bui, Masayoshi Kuwano, Naotake Ogasawara, Richard A. Daniel, Robert M. Cleverley, Robyn Emmins, Christopher N Hoyland, Waldemar Vollmer
Publikováno v:
The EMBO Journal. 30:4931-4941
Teichoic acids and acidic capsular polysaccharides are major anionic cell wall polymers (APs) in many bacteria, with various critical cell functions, including maintenance of cell shape and structural integrity, charge and cation homeostasis, and mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::857dd699e0663d464cf200410470c547
https://doi.org/10.1038/emboj.2011.358
https://doi.org/10.1038/emboj.2011.358
Autor:
Hendrik Szurmant, James A. Hoch, Tatsuya Fukushima, Isako Furihata, Richard A. Daniel, Robyn Emmins
Publikováno v:
Molecular Microbiology. 79:503-522
The YycG sensor histidine kinase co-ordinates cell wall remodelling with cell division in Gram-positive bacteria by controlling the transcription of genes for autolysins and their inhibitors. Bacillus subtilis YycG senses cell division and is enzymat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b43f7163b06b1a736ebb7d50bc8a2574
https://doi.org/10.1111/j.1365-2958.2010.07464.x
https://doi.org/10.1111/j.1365-2958.2010.07464.x
Autor:
Jeff Errington, David H. Edwards, Richard A. Daniel, Robyn Emmins, Leendert W. Hamoen, Dennis Claessen
Publikováno v:
Molecular Microbiology. 68:1029-1046
The characteristic shape of bacterial cells is mainly determined by the cell wall, the synthesis of which is orchestrated by penicillin-binding proteins (PBPs). Rod-shaped bacteria have two distinct modes of cell wall synthesis, involved in cell elon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5410adc8a8aa02e68317f46926a7b251
https://doi.org/10.1111/j.1365-2958.2008.06210.x
https://doi.org/10.1111/j.1365-2958.2008.06210.x
Autor:
John Tonkyn, Alan Peter Lewis, Joanna Cordy, Y. Chen, Andrew I. Bayliffe, Aili L. Lazaar, William Powley, Mary Birchler, Philippe Bareille, Peter J. Morley, Robyn Emmins, Tracey J. Wright, Robert Wilson
Publikováno v:
Clinical and experimental immunology. 182(2)
Summary During clinical trials of a tumour necrosis factor (TNF)-R1 domain antibody (dAb™) antagonist (GSK1995057), infusion reactions consistent with cytokine release were observed in healthy subjects with high levels of a novel, pre-existing huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ca85a6b1dc4a6a9cac6dd540008463
https://pubmed.ncbi.nlm.nih.gov/26178412
https://pubmed.ncbi.nlm.nih.gov/26178412