Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Robyn D. Gartrell"'
Autor:
Masih Tazhibi, Nicholas McQuillan, Hong-Jian Wei, Matthew Gallitto, Ethan Bendau, Andrea Webster Carrion, Xander Berg, Danae Kokossis, Xu Zhang, Zhiguo Zhang, Chia-Ing Jan, Akiva Mintz, Robyn D. Gartrell, Hasan R. Syed, Adriana Fonseca, Jovana Pavisic, Luca Szalontay, Elisa E. Konofagou, Stergios Zacharoulis, Cheng-Chia Wu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Diffuse midline glioma (DMG) is a pediatric tumor with dismal prognosis. Systemic strategies have been unsuccessful and radiotherapy (RT) remains the standard-of-care. A central impediment to treatment is the blood–brain barrier
Externí odkaz:
https://doaj.org/article/159f8aa414984404a35643a5ecfeb319
Autor:
Kris Ann P. Schultz, Murali Chintagumpala, Jin Piao, Kenneth S. Chen, Rachana Shah, Robyn D. Gartrell, Emily Christison-Lagay, Farzana Pashnakar, Jesse L. Berry, Allison F. O’Neill, Lauren M. Vasta, Ashley Flynn, Sarah G. Mitchell, Brittani KN. Seynnaeve, Jeremy Rosenblum, Samara L. Potter, Junne Kamihara, Carlos Rodriguez-Galindo, Douglas S. Hawkins, Theodore W. Laetsch
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100024- (2023)
While all childhood cancers are rare, tumors that are particularly infrequent or underrepresented within pediatrics are studied under the umbrella of the Children’s Oncology Group Rare Tumor committee, divided into the Retinoblastoma and Infrequent
Externí odkaz:
https://doaj.org/article/1d78ae7efc7f48d693fb7d9771fddd5b
Autor:
Shuobo Boboila, Shunpei Okochi, Debarshi Banerjee, Sunjay Barton, Cherease Street, Ariela L. Zenilman, Qi Wang, Robyn D. Gartrell, Yvonne M. Saenger, David Welch, Cheng-Chia Wu, Angela Kadenhe-Chiweshe, Darrell J. Yamashiro, Eileen P. Connolly
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17399- (2023)
Purpose: The mortality in patients with MYCN-amplified high-risk neuroblastoma remains greater than 50% despite advances in multimodal therapy. Novel therapies are urgently needed that requires preclinical evaluation in appropriate mice models. Combi
Externí odkaz:
https://doaj.org/article/fa27762c9bb44152888c6166e7048148
Autor:
Robyn D. Gartrell, Thomas Enzler, Pan S. Kim, Benjamin T. Fullerton, Ladan Fazlollahi, Andrew X. Chen, Hanna E. Minns, Subha Perni, Stuart P. Weisberg, Emanuelle M. Rizk, Samuel Wang, Eun Jeong Oh, Xinzheng V. Guo, Codruta Chiuzan, Gulam A. Manji, Susan E. Bates, John Chabot, Beth Schrope, Michael Kluger, Jean Emond, Raul Rabadán, Donna Farber, Helen E. Remotti, David P. Horowitz, Yvonne M. Saenger
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Patients with pancreatic ductal adenocarcinoma (PDAC) have a grim prognosis despite complete surgical resection and intense systemic therapies. While immunotherapies have been beneficial with many different types of solid tumors, they have almost uni
Externí odkaz:
https://doaj.org/article/0131345f4fd04318adad2908f6c64b94
Autor:
Andrew X. Chen, Robyn D. Gartrell, Junfei Zhao, Pavan S. Upadhyayula, Wenting Zhao, Jinzhou Yuan, Hanna E. Minns, Athanassios Dovas, Jeffrey N. Bruce, Anna Lasorella, Antonio Iavarone, Peter Canoll, Peter A. Sims, Raul Rabadan
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Background Macrophages are the most common infiltrating immune cells in gliomas and play a wide variety of pro-tumor and anti-tumor roles. However, the different subpopulations of macrophages and their effects on the tumor microenvironment r
Externí odkaz:
https://doaj.org/article/d861900a897a459a945d33e79ba44a01
Autor:
Michael R. Moore, Isabel D. Friesner, Emanuelle M. Rizk, Benjamin T. Fullerton, Manas Mondal, Megan H. Trager, Karen Mendelson, Ijeuru Chikeka, Tahsin Kurc, Rajarsi Gupta, Bethany R. Rohr, Eric J. Robinson, Balazs Acs, Rui Chang, Harriet Kluger, Bret Taback, Larisa J. Geskin, Basil Horst, Kevin Gardner, George Niedt, Julide T. Celebi, Robyn D. Gartrell-Corrado, Jane Messina, Tammie Ferringer, David L. Rimm, Joel Saltz, Jing Wang, Rami Vanguri, Yvonne M. Saenger
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Accurate prognostic biomarkers in early-stage melanoma are urgently needed to stratify patients for clinical trials of adjuvant therapy. We applied a previously developed open source deep learning algorithm to detect tumor-infiltrating lymph
Externí odkaz:
https://doaj.org/article/8d415bf272d94264979172564903d21c
Autor:
Balazs Acs, Fahad Shabbir Ahmed, Swati Gupta, Pok Fai Wong, Robyn D. Gartrell, Jaya Sarin Pradhan, Emanuelle M. Rizk, Bonnie Gould Rothberg, Yvonne M. Saenger, David L. Rimm
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Histology data exists for many cancer samples and the ability to automatically image this data may provide prognostic information. Here, the authors generated an algorithm to measure tumour infiltrating lymphocytes in melanoma histology specimens and
Externí odkaz:
https://doaj.org/article/aa7ab2f3684448649179b824d976a4d8
Autor:
Jared M. Newton, Aurelie Hanoteau, Hsuan-Chen Liu, Angelina Gaspero, Falguni Parikh, Robyn D. Gartrell-Corrado, Thomas D. Hart, Damya Laoui, Jo A. Van Ginderachter, Neeraja Dharmaraj, William C. Spanos, Yvonne Saenger, Simon Young, Andrew G. Sikora
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-21 (2019)
Abstract Background Immune checkpoint inhibitors (ICIs) for solid tumors, including those targeting programmed cell death 1 (PD-1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), have shown impressive clinical efficacy, however, most patien
Externí odkaz:
https://doaj.org/article/5865ba33af83434c8d59aa844ab92960
Autor:
Aurelie Hanoteau, Jared M. Newton, Rosemarie Krupar, Chen Huang, Hsuan-Chen Liu, Angelina Gaspero, Robyn D. Gartrell, Yvonne M. Saenger, Thomas D. Hart, Saskia J. Santegoets, Damya Laoui, Chad Spanos, Falguni Parikh, Padmini Jayaraman, Bing Zhang, Sjoerd H. Van der Burg, Jo A. Van Ginderachter, Cornelis J. M. Melief, Andrew G. Sikora
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-19 (2019)
Abstract Background Chemoradiotherapy (CRT) remains one of the most common cancer treatment modalities, and recent data suggest that CRT is maximally effective when there is generation of an anti-tumoral immune response. However, CRT has also been sh
Externí odkaz:
https://doaj.org/article/529ee5858b424de6b4b551d4e3d1d450
Autor:
Mara De Martino, Oscar Padilla, Camille Daviaud, Cheng-Chia Wu, Robyn D. Gartrell, Claire Vanpouille-Box
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) is among the most aggressive of brain tumors and confers a dismal prognosis despite advances in surgical technique, radiation delivery methods, chemotherapy, and tumor-treating fields. While immunotherapy (IT) has improved the care
Externí odkaz:
https://doaj.org/article/25d1ae30496342289d91bb44be7019f2