Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Robyn A. Lindner"'
Autor:
Robyn Ann Lindner
Publikováno v:
The Medical journal of Australia. 208(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4630faa4e92915e3f64548a397e5a5b
https://pubmed.ncbi.nlm.nih.gov/29438640
https://pubmed.ncbi.nlm.nih.gov/29438640
Publikováno v:
The Medical journal of Australia. 206(9)
Cognitive biases in decision making may make it difficult for clinicians to reconcile evidence of overuse with highly ingrained prior beliefs and intuition. Such biases can predispose clinicians towards low value care and may limit the impact of rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05165e59cda8f9ff1dad3f92b1ef02e
https://pubmed.ncbi.nlm.nih.gov/28490292
https://pubmed.ncbi.nlm.nih.gov/28490292
Autor:
Christopher M. Dobson, Christina Redfield, Robyn A. Lindner, Denis Canet, Charles E. Lyon, Helena Hernández, John A. Carver
The unfolding of the apo and holo forms of bovine alpha-lactalbumin (alpha-LA) upon reduction by dithiothreitol (DTT) in the presence of the small heat-shock protein alpha-crystallin, a molecular chaperone, has been monitored by visible and UV absorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9116e477db88879141bf79e8f8c368de
https://ora.ox.ac.uk/objects/uuid:b53fb0e9-bb90-4a9a-9029-0f612b87274b
https://ora.ox.ac.uk/objects/uuid:b53fb0e9-bb90-4a9a-9029-0f612b87274b
Autor:
John A. Carver, Elizabeth Vierling, Andrew Baldwin, Glyn L. Devlin, Agata Rekas, Justin L. P. Benesch, Eman Basha, Florian Stengel, Carol V. Robinson, J. Andrew Aquilina, Joseph Horwitz, Robyn A. Lindner
SummaryThe function of ScHSP26 is thermally controlled: the heat shock that causes the destabilization of target proteins leads to its activation as a molecular chaperone. We investigate the structural and dynamical properties of ScHSP26 oligomers th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32dc96a60ea2b110db0fe0314992410
https://ora.ox.ac.uk/objects/uuid:194c62c3-2d41-4e1f-8956-a003b3448fcd
https://ora.ox.ac.uk/objects/uuid:194c62c3-2d41-4e1f-8956-a003b3448fcd
Autor:
Lucille T. Sebastian, Michael Hsu, Andrew John Sloane, Peter T. P. Bye, Jenny L. Harry, Susanne K. Pedersen, Robyn A. Lindner, Sindhu S. Prasad, Ron P. Weinberger, Michael D. Robinson
Publikováno v:
Molecular & Cellular Proteomics. 4:1052-1060
Circulating antibodies can be used to probe protein arrays of body fluids, prepared by two-dimensional gel electrophoresis, for antigenic biomarker detection. However, detected proteins, particularly low abundance antigens, often remain unidentifiabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e120cdb4d79e4ebe8f45c7c821cd50c4
https://doi.org/10.1074/mcp.m400175-mcp200
https://doi.org/10.1074/mcp.m400175-mcp200
Autor:
Roy A. Quinlan, John A. Carver, Joseph Horwitz, J. Andrew Aquilina, Carol V. Robinson, Ming Der Perng, Mark J. Walker, Agata Rekas, Robyn A. Lindner, Teresa M. Treweek
Publikováno v:
FEBS Journal. 272:711-724
alpha-Crystallin is the principal lens protein which, in addition to its structural role, also acts as a molecular chaperone, to prevent aggregation and precipitation of other lens proteins. One of its two subunits, alphaB-crystallin, is also express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4b65586cf3397d848c00b2f1dfe9d2b
https://doi.org/10.1111/j.1742-4658.2004.04507.x
https://doi.org/10.1111/j.1742-4658.2004.04507.x
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 24:949-954
Objective—The involvement of transition metals in atherosclerosis is controversial. Some epidemiological studies have reported a relationship between iron (Fe) and cardiovascular disease, whereas others have not. Experimental studies have reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3974f2546fb4395512ded5c7529bd6b
https://doi.org/10.1161/01.atv.0000124892.90999.cb
https://doi.org/10.1161/01.atv.0000124892.90999.cb
Publikováno v:
Biochemical Journal. 354:79-87
In vivo, α-crystallin and other small heat-shock proteins (sHsps) act as molecular chaperones to prevent the precipitation of ‘substrate’ proteins under stress conditions through the formation of a soluble sHsp–substrate complex. Using a range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b7c3a3b974890880eb960ad97eaffc1
https://doi.org/10.1042/bj3540079
https://doi.org/10.1042/bj3540079
Autor:
John A. Carver, Monika Ehrnsperger, Joachim Behlke, Johannes Buchner, Alexey Kotlyarov, Matthias Gaestel, Gudrun Lutsch, Gennaro Esposito, Robyn A. Lindner
Publikováno v:
European Journal of Biochemistry. 267:1923-1932
Under conditions of cellular stress, small heat shock proteins (sHsps), e.g. Hsp25, stabilize unfolding proteins and prevent their precipitation from solution. 1H NMR spectroscopy has shown that mammalian sHsps possess short, polar and highly flexibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1898e2903c55a88f63e06928daba76
https://doi.org/10.1046/j.1432-1327.2000.01188.x
https://doi.org/10.1046/j.1432-1327.2000.01188.x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1476:265-278
In humans, the crystallin proteins of the ocular lens become yellow-coloured and fluorescent with ageing. With the development of senile nuclear cataract, the crystallins become brown and additional fluorophores are formed. The mechanism underlying c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523bda1e6233c39f7d642c3eaa685f9f
https://doi.org/10.1016/s0167-4838(99)00234-4
https://doi.org/10.1016/s0167-4838(99)00234-4