Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Robson X Faria"'
Autor:
André L A Souza, Robson X Faria, Kátia S Calabrese, Daiane J Hardoim, Noemi Taniwaki, Luiz A Alves, Salvatore G De Simone
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157673 (2016)
Tropical diseases caused by parasitic infections continue to cause socioeconomic distress worldwide. Among these, Chagas disease has become a great concern because of globalization. Caused by Trypanosoma cruzi, there is an increasing need to discover
Externí odkaz:
https://doaj.org/article/b593f780cac047239f7290d1f183f7db
Autor:
Hercules R Freitas, Gabriel Ferraz, Gustavo C Ferreira, Victor T Ribeiro-Resende, Luciana B Chiarini, José Luiz M do Nascimento, Karen Renata H Matos Oliveira, Tiago de Lima Pereira, Leonardo G B Ferreira, Regina C Kubrusly, Robson X Faria, Anderson Manoel Herculano, Ricardo A de Melo Reis
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153677 (2016)
Neuroglia interactions are essential for the nervous system and in the retina Müller cells interact with most of the neurons in a symbiotic manner. Glutathione (GSH) is a low-molecular weight compound that undertakes major antioxidant roles in neuro
Externí odkaz:
https://doaj.org/article/9f8fdaeb1e2846b984ce0a93ff95fa88
Autor:
Rafaelle Vinturelle, Taissa da Silva Cabral, Pamella C.O. de Oliveira, Juliana P. Salles, Juliana V. Faria, Guilherme P. Teixeira, Robson X. Faria, Márcia C.C. Veloso, Gilberto A. Romeiro, Evelyze Folly das Chagas
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101704- (2024)
The Terminalia catappa L. tree is an ornamental and shade tree producter of a large amount of biological waste sent to landfills. Therefore, this plant constitutes so-called municipal solid wood waste (MSWW), which causes undesirable impacts on the e
Externí odkaz:
https://doaj.org/article/ddd358ed79324af1ae42d06de37f02ef
Autor:
Luis F. Quejada, Andrea X. Hernandez, Luis C. Chitiva, Claudia P. Bravo-Chaucanés, Yerly Vargas-Casanova, Robson X. Faria, Geison M. Costa, Claudia M. Parra-Giraldo
Publikováno v:
Journal of Fungi, Vol 10, Iss 7, p 464 (2024)
Invasive fungal disease causes high morbidity and mortality among immunocompromised patients. Resistance to conventional antifungal drugs and the toxicity associated with high doses highlight the need for effective antifungal therapies. In this study
Externí odkaz:
https://doaj.org/article/dc29c57a8df44a9498923482e2866188
Autor:
Bettina Quintanilha Magalhães, Francisco P. Machado, Paola S. Sanches, Bárbara Lima, Deborah Quintanilha Falcão, Natalia von Ranke, Murilo Lamim Bello, Carlos Rangel Rodrigues, Marcelo Guerra Santos, Leandro Rocha, Robson X. Faria
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 911 (2022)
P2X7R is a purinergic receptor with broad expression throughout the body, especially in immune system cells. P2X7R activation causes inflammatory mediators to release, including interleukin-1β (IL-1β), the processing and release of which are critic
Externí odkaz:
https://doaj.org/article/264f9bfb90d14c8980322768121d2270
Autor:
Juliana P S, Dos Santos, Ruan Carlos B, Ribeiro, Juliana V, Faria, Murilo L, Bello, Carolina G S, Lima, Fernanda P, Pauli, Amanda A, Borges, David R, Rocha, Matheus G, Moraes, Luana S M, Forezi, Vitor F, Ferreira, Robson X, Faria, Fernando de C, da Silva
Publikováno v:
Journal of bioenergetics and biomembranes. 54(5-6)
The P2X7 receptor (P2X7R) is an ion channel that promotes the passage of ions through the membrane through brief stimulation once activated by ATP, its endogenous opener. However, prolonged stimulation with ATP, which occurs in pathological processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::659a5d3144030c9382cea82f2f629710
https://pubmed.ncbi.nlm.nih.gov/36070071
https://pubmed.ncbi.nlm.nih.gov/36070071
Autor:
Robson X. Faria, P. A. F. Pacheco
Publikováno v:
Biomedical Journal of Scientific & Technical Research. 30
Chagas disease, also attributed to American trypanosomiasis, is an anthropozoonosis caused by the parasite Trypanosoma cruzi and transmitted by insect triatomine vectors...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5091a66db2ee994395b6aaa95ef31916
https://doi.org/10.26717/bjstr.2020.30.005026
https://doi.org/10.26717/bjstr.2020.30.005026
Autor:
Robson X. Faria, Vinícius R. Campos, Raíssa Maria Dos Santos Galvão, Murilo L. Bello, Vitor F. Ferreira, Fernanda P. Pauli, Thais de B. da Silva, Luana da S. M. Forezi, Kathya N.K. Ji, Ana F.M. Faria, Jackson A. L. C. Resende, Fernando de C. da Silva
Publikováno v:
Bioorganic Chemistry. 116:105250
1,2,3-triazole heterocycles stand out in medicinal chemistry for having great structural diversity and bioactivities. In this study, two series of triazoles were synthesized. One was obtained by the 1,3-dipolar cycloaddition reaction between ethyl cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e089f1f346680e8cd1971f0b716b9840
https://doi.org/10.1016/j.bioorg.2021.105250
https://doi.org/10.1016/j.bioorg.2021.105250
Autor:
Daniel T. G. Gonzaga, Felipe H. Oliveira, N. L. von Ranke, G. Q. Pinho, Juliana P. Salles, Murilo L. Bello, Carlos R. Rodrigues, Helena C. Castro, Hellen V. C. M. de Souza, Caroline R. C. Reis, Rennan P. P. Leme, João C. M. Mafra, Luiz C. S. Pinheiro, Lucas V. B. Hoelz, Nubia Boechat, Robson X. Faria
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 7 (2019)
Frontiers in Chemistry, Vol 7 (2019)
Twenty new 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole analogs were synthetized to develop P2X7 receptor (P2X7R) inhibitors. P2X7R inhibition in vitro was evaluated in mouse peritoneal macrophages, HEK-293 cells transfected with hP2X7R (dye uptake assay),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a374e0d5c1697e3a638c62ad372a0b0
https://doi.org/10.3389/fchem.2019.00261
https://doi.org/10.3389/fchem.2019.00261
Autor:
Magda F, Serra, Josiane S, Neves, Gina C, Couto, Amanda C, Cotias, Camila R, Pão, Priscilla C, Olsen, Katharinne I Moraes, de Carvalho, Edna A, Anjos-Valotta, Robson X, Faria, Jorge C S, Costa, Renato S B, Cordeiro, Patricia M R, Silva, Marco A, Martins
Publikováno v:
Anesthesiology. 124(1)
Inhaled lidocaine antagonized bronchospasm in animal models and patients, but adverse effects limited its efficacy. This study evaluated the antibronchospasm potential of the analog JM25-1, exploring in vitro mechanisms and translation to an animal m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1173a511828e676cc8a6c465fc2a2734
https://pubmed.ncbi.nlm.nih.gov/26669988
https://pubmed.ncbi.nlm.nih.gov/26669988