SARS-CoV-2 uses CD4 to infect T helper lymphocytes

Autor: Natalia S Brunetti, Gustavo G Davanzo, Diogo de Moraes, Allan JR Ferrari, Gabriela F Souza, Stéfanie Primon Muraro, Thiago L Knittel, Vinicius O Boldrini, Lauar B Monteiro, João Victor Virgílio-da-Silva, Gerson S Profeta, Natália S Wassano, Luana Nunes Santos, Victor C Carregari, Artur HS Dias, Flavio P Veras, Lucas A Tavares, Julia Forato, Icaro MS Castro, Lícia C Silva-Costa, André C Palma, Eli Mansour, Raisa G Ulaf, Ana F Bernardes, Thyago A Nunes, Luciana C Ribeiro, Marcus V Agrela, Maria Luiza Moretti, Lucas I Buscaratti, Fernanda Crunfli, Raissa G Ludwig, Jaqueline A Gerhardt, Natália Munhoz-Alves, Ana Maria Marques, Renata Sesti-Costa, Mariene R Amorim, Daniel A Toledo-Teixeira, Pierina Lorencini Parise, Matheus Cavalheiro Martini, Karina Bispos-dos-Santos, Camila L Simeoni, Fabiana Granja, Virgínia C Silvestrini, Eduardo B de Oliveira, Vitor M Faca, Murilo Carvalho, Bianca G Castelucci, Alexandre B Pereira, Laís D Coimbra, Marieli MG Dias, Patricia B Rodrigues, Arilson Bernardo SP Gomes, Fabricio B Pereira, Leonilda MB Santos, Louis-Marie Bloyet, Spencer Stumpf, Marjorie C Pontelli, Sean Whelan, Andrei C Sposito, Robson F Carvalho, André S Vieira, Marco AR Vinolo, André Damasio, Licio Velloso, Ana Carolina M Figueira, Luis LP da Silva, Thiago Mattar Cunha, Helder I Nakaya, Henrique Marques-Souza, Rafael E Marques, Daniel Martins-de-Souza, Munir S Skaf, Jose Luiz Proenca-Modena, Pedro MM Moraes-Vieira, Marcelo A Mori, Alessandro S Farias

Publikováno v: eLife, Vol 12 (2023)

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent of a major global outbreak of respiratory tract disease known as Coronavirus Disease 2019 (COVID-19). SARS-CoV-2 infects mainly lungs and may cause several immune-related c

Externí odkaz: https://doaj.org/article/99a35dd8fb984baea7fc8271d68472e7

MicroRNA-499 expression distinctively correlates to target genes sox6 and rod1 profiles to resolve the skeletal muscle phenotype in Nile tilapia.

Autor: Pedro G Nachtigall, Marcos C Dias, Robson F Carvalho, Cesar Martins, Danillo Pinhal

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0119804 (2015)

A class of small non-coding RNAs, the microRNAs (miRNAs), has been shown to be essential for the regulation of specific cell pathways, including skeletal muscle development, maintenance and homeostasis in vertebrates. However, the relative contributi

Externí odkaz: https://doaj.org/article/69bbd8a36b0043d29ce586c0e317437e

Decreased miR-497-5p Suppresses IL-6 Induced Atrophy in Muscle Cells

Autor: Paula P. Freire, Sarah S. Cury, Letícia O. Lopes, Geysson J. Fernandez, Jianming Liu, Leonardo Nazario de Moraes, Grasieli de Oliveira, Jakeline S. Oliveira, Diogo de Moraes, Otavio Cabral-Marques, Maeli Dal-Pai-Silva, Xiaoyun Hu, Da-Zhi Wang, Robson F. Carvalho

Publikováno v: Cells, Vol 10, Iss 12, p 3527 (2021)

Interleukin-6 (IL-6) is a pro-inflammatory cytokine associated with skeletal muscle wasting in cancer cachexia. The control of gene expression by microRNAs (miRNAs) in muscle wasting involves the regulation of thousands of target transcripts. However

Externí odkaz: https://doaj.org/article/271ea18b0cf04791ab9a7a2d13ce4e9a

SARS-CoV-2 infection induces the production of autoantibodies in severe COVID-19 patients in an age-dependent manner

Autor: Dennyson Leandro M Fonseca, Igor Salerno Filgueiras, Alexandre HC Marques, Elroy Vojdani, Gilad Halpert, Yuri Ostrinski, Gabriela Crispim Baiocchi, Desirée Rodrigues Plaça, Paula P. Freire, Shahab Zaki Pour, Guido Moll, Rusan Catar, Yael Bublil Lavi, Jonathan I. Silverberg, Jason Zimmerman, Gustavo Cabral de Miranda, Robson F Carvalho, Taj Ali Khan, Harald Heidecke, Rodrigo JS Dalmolin, Andre Ducati Luchessi, Hans D. Ochs, Lena F. Schimke, Howard Amital, Gabriela Riemekasten, Israel Zyskind, Avi Z Rosenberg, Aristo Vojdani, Yehuda Shoenfeld, Otavio Cabral-Marques

Age is a significant risk factor for the coronavirus disease 2019 (COVID-19) outcomes due to immunosenescence and certain age-dependent medical conditions (e.g., obesity, cardiovascular disorder, diabetes, chronic respiratory disease). However, despi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90cd94b9df69136e678edcba69145175
https://doi.org/10.1101/2022.12.04.22282902

Additional file 1 of Integrative microRNAome analysis of skeletal muscle of Colossoma macropomum (tambaqui), Piaractus mesopotamicus (pacu), and the hybrid tambacu, based on next-generation sequencing data

Autor: Fantinatti, Bruno E. A., Perez, Erika S., Zanella, Bruna T. T., Jéssica S. Valente, Tassiana G. De Paula, Mareco, Edson A., Robson F. Carvalho, Piazza, Silvano, Denti, Michela A., Dal-Pai-Silva, Maeli

Additional file 1. Read number information. Read number throughout filtering process. Data showing the decrease number of reads according to filtering steps performed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d406385d2796da8e8fe9fb6b1ef943