Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Robinson, John E"'
Autor:
Robinson, John E.
Publikováno v:
Full text available from Digital Dissertations.
Dissertations (Ed. D.)--Rowan University, 2009.
Typescript. "UMI Number: 3379866"--T.p. verso. Includes bibliographical references.
Typescript. "UMI Number: 3379866"--T.p. verso. Includes bibliographical references.
Externí odkaz:
http://proquest.umi.com/login?COPT=REJTPUcyODcrNTQ4NyszYjEwJklOVD0wJlZFUj0y&clientId=11223
Autor:
Fathi, Amir T., Arowojolu, Omotayo, Swinnen, Ian, Sato, Takashi, Rajkhowa, Trivikram, Small, Donald, Marmsater, Fredrik, Robinson, John E., Gross, Stefan David, Martinson, Matthew, Allen, Shelley, Kallan, Nicholas C., Levis, Mark
Publikováno v:
In Leukemia Research February 2012 36(2):224-231
Autor:
Jackson, Leila J., Pheneger, Jed A., Pheneger, Tracy J., Davis, Gregg, Wright, A. Dale, Robinson, John E., Allen, Shelley, Munson, Mark C., Carter, Laura L.
Publikováno v:
In Cellular Immunology 2012 272(2):200-213
Autor:
Robinson, John E., Marx, Lori O.
Publikováno v:
The American Journal of Nursing, 1985 Feb 01. 85(2), 158-161.
Externí odkaz:
https://www.jstor.org/stable/3463838
Autor:
Piscopio, Anthony D, Robinson, John E
Publikováno v:
In Current Opinion in Chemical Biology 2004 8(3):245-254
Publikováno v:
In Tetrahedron Letters 1999 40(16):3105-3108
Autor:
A. Dale Wright, Laura L. Carter, Mark C. Munson, Robinson John E, Shelley Allen, Leila J. Jackson, T. Gregg Davis, Tracy Pheneger, Pheneger Jed
Publikováno v:
Cellular Immunology. 272:200-213
PIM kinases are a family of three serine/threonine kinases expressed following T cell activation. Using potent selective small molecule antagonists of PIM-1/3 kinases, we demonstrate a potential role for these enzymes in naïve and effector CD4+ T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e0da34574e73330b0f19aadeeb9bb2
https://doi.org/10.1016/j.cellimm.2011.10.011
https://doi.org/10.1016/j.cellimm.2011.10.011
Autor:
John Bruin, William Hamilton, Emma Kinghorn, Kenneth S. Cameron, Paul Westwood, Jiaqiang Cai, Kathryn Everett, Clive Long, Maureen Dempster, Chris Claxton, Xavier Fradera, D. Jonathan Bennett, Robinson John E, Simone Belshaw, Philip Jones, Wullie Arbuckle, Mark Baugh, Iain Martin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:932-935
Based on the theoretical understanding of the in vivo lysosomotropism, by adjusting the pka of basic nitrogen containing cathepsin S inhibitors, a set of compounds with pka 6–8 were identified to have excellent cell based Lip10 activity, yet avoidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476635684754e9aff8bc8031c6950b59
https://doi.org/10.1016/j.bmcl.2010.12.065
https://doi.org/10.1016/j.bmcl.2010.12.065
Autor:
Hortense Deronzier, Cecile Dorleans, John Waller, Laurent Saniere, Andre Fouquet, Fiona Elizabeth Andrews, Mark Baugh, J.C.M. Uitdehaag, George McGarry, Phil Jones, Ann Mitchell, Emma Kinghorn, Eric Nicolai, Wilson Caulfield, Zoran Rankovic, Dominique Potin, Mario van Zeeland, Wullie Arbuckle, Jennifer Kerr, Jiaqiang Cai, Mark Wheaton Anderson, Iain Martin, Maureen Dempster, Ashvin Mistry, François Chevallier, William Finlay, Clive Long, Robinson John E, Xavier Fradera, Paul Westwood, Iain Cumming
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:6237-6241
Several structure-guided optimisation strategies were explored in order to improve the hERG selectivity profile of cathepsin K inhibitor 1 , whilst maintaining its otherwise excellent in vitro and in vivo profile. Ultimately, attenuation of c log P a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcfb747e700da9944dc50d293047fcc
https://doi.org/10.1016/j.bmcl.2010.08.101
https://doi.org/10.1016/j.bmcl.2010.08.101
Autor:
D. Jonathan Bennett, Kenneth S. Cameron, John Bruin, Mario van Zeeland, Xavier Fradera, J.C.M. Uitdehaag, Emma Kinghorn, Jiaqiang Cai, Maureen Dempster, Paul Westwood, Lucy Popplestone, Mark Baugh, Robinson John E, William Hamilton, Clive Long
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:4507-4510
Using computer aided modelling studies, a new extended P2/S2 interaction was identified. This extended region can accommodate a variety of functional groups, such as aryls and basic amines. It was discovered that the N3 nitrogen of the pyrimidine-2-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a4ef389f50e29987f14e5b21317077
https://doi.org/10.1016/j.bmcl.2010.06.043
https://doi.org/10.1016/j.bmcl.2010.06.043