Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Robina M, Meyer"'
Autor:
Lukas Berger, Robina M. Meyer, Sebastian Nehring, Joerg Nerkamp, Wolfgang Friess, Stefan Scheler
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 160:134-142
Monoclonal antibodies (mAbs) are valuable tools both in therapy and in diagnostic. Their tendency to aggregate is a serious concern. Since a mAb drug substance (DS) is composed of different variants, it is important for manufacturers to know the beha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11207a6dc4a754201069c4fbe2410c9f
https://doi.org/10.1016/j.ejpb.2021.01.006
https://doi.org/10.1016/j.ejpb.2021.01.006
Autor:
Robina M, Meyer, Sofya, Aleshkevich, Lukas, Berger, Joerg, Nerkamp, Stefan, Scheler, Wolfgang, Friess
Publikováno v:
International Journal of Pharmaceutics. 621:121760
Biopharmaceutical products are subject to in depth analysis to ensure and improve their safety and efficacy. As part of this effort the stability and aggregation mechanisms of the therapeutic protein is characterized over the whole life cycle. The st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37853cb81e97de020afce507a4ef1ac
https://doi.org/10.1016/j.ijpharm.2022.121760
https://doi.org/10.1016/j.ijpharm.2022.121760
Autor:
Lukas Berger, Wolfgang Friess, Stefan Scheler, Robina M. Meyer, Sebastian Nehring, Joerg Nerkamp
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 158
Biopharmaceutical products contain conformational and chemical variants, that are typically well characterized regarding identity and activity. However, little is known about their self-interaction propensity and tendency to unfold, which are critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02d956edb76b44a1801829296c9372b
https://pubmed.ncbi.nlm.nih.gov/33221370
https://pubmed.ncbi.nlm.nih.gov/33221370