Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Robin X Luo"'
Autor:
Rhonda Kimmel, Sheryl M. Petersen, Sharon T. Thomas, Robin X Luo, Gerald B. Pier, Binyam Bezabeh, Zengzu Lai, John R. Schreiber
Publikováno v:
Vaccine. 23:3264-3271
Pseudomonas aeruginosa is a serious human pathogen in a variety of patient groups including those with burns, hospitalized in intensive care, cystic fibrosis and neutropenia. Since there is no vaccine available, passive antibody prophylaxis against p
Autor:
Robin X. Luo, Anjali Dahiya, J. William Harbour, H.Steven Zhang, Douglas C. Dean, Antonio Postigo, Mark Gavin, Duanduan Ma
Publikováno v:
Cell. 101:79-89
We present evidence that Rb forms a repressor containing histone deacetylase (HDAC) and the hSWI/SNF nucleosome remodeling complex, which inhibits transcription of genes for cyclins E and A and arrests cells in the G1 phase of the cell cycle. Phospho
Autor:
Douglas C. Dean, Robin X. Luo
Publikováno v:
JNCI Journal of the National Cancer Institute. 91:1288-1294
Extensive studies in the past few years have begun to demonstrate that chromosome structure plays a critical role in transcriptional regulation. Two highly conserved mechanisms for altering chromosome structure have been identified: 1) post-translati
Autor:
Kevin N. B. Chow, Robin X. Luo, Steven J. Weintraub, Song He, Steven H. Zhang, Douglas C. Dean
Publikováno v:
Nature. 375:812-816
The retinoblastoma tumour-suppressor protein (Rb) belongs to a family that share a motif known as the pocket. The pocket was originally identified as the region of Rb required for binding to oncoproteins from DNA tumour viruses, which disrupt the bin
Autor:
Robert W. Maitta, Liise Anne Pirofski, Qing Chang, Bradley Witover, Robin X. Luo, Kausik Datta, Krishanthi Subramaniam
The features of protective murine antibodies to the Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM) have been rigorously investigated; however, the characteristics of protective human antibodies to GXM have not been defined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57cc9ad94b840576289abfe74a19af7
https://europepmc.org/articles/PMC470673/
https://europepmc.org/articles/PMC470673/
Oncoproteins from DNA tumor viruses such as adenovirus E1a, simian virus 40 T antigen, and human papillomavirus E7 contain an LXCXE sequence, which they use to bind the retinoblastoma protein (Rb) and inhibit its function. Cellular proteins such as h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305d360c87b8914cbe9d395dd20d68bd
https://europepmc.org/articles/PMC86207/
https://europepmc.org/articles/PMC86207/
Publikováno v:
Cell. 98(6)
We present evidence that phosphorylation of the C-terminal region of Rb by Cdk4/6 initiates successive intramolecular interactions between the C-terminal region and the central pocket. The initial interaction displaces histone deacetylase from the po
Publikováno v:
Cell. 92(4)
Previously, we found that Rb can actively repress transcription of cell cycle genes by binding and inactivating transcription factors at the promoter. Here, we demonstrate that Rb can also repress transcription of endogenous cell cycle genes containi
Autor:
Binyam Bezabeh, Elodie Foulquier, Véronique Garambois, Martine Pugnière, Marc Ychou, André Pèlegrin, Fabienne Glaussel, Robin X Luo
Publikováno v:
BMC Cancer
BMC Cancer, BioMed Central, 2004, 4, pp.75. ⟨10.1186/1471-2407-4-75⟩
BMC Cancer, Vol 4, Iss 1, p 75 (2004)
BMC Cancer, 2004, 4, pp.75. ⟨10.1186/1471-2407-4-75⟩
BMC Cancer, BioMed Central, 2004, 4, pp.75. ⟨10.1186/1471-2407-4-75⟩
BMC Cancer, Vol 4, Iss 1, p 75 (2004)
BMC Cancer, 2004, 4, pp.75. ⟨10.1186/1471-2407-4-75⟩
Background Human monoclonal antibodies (MAbs) are needed for colon cancer radioimmunotherapy (RIT) to allow for repeated injections. Carcinoembryonic antigen (CEA) being the reference antigen for immunotargeting of these tumors, we developed human an
Autor:
Douglas C. Dean, Duanduan Ma, Antonio Postigo, Mark Gavin, William Harbour, Steve Zhang, Robin X. Luo, Anjali Dahiya
Publikováno v:
Nature Genetics. 27:55-55
Control of exit from G1 and S phases of the cell cycle by histone deacetylase–Rb-hSWI/SNF and Rb-hSWI/SNF repressor complexes