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pro vyhledávání: '"Robin Willenbring"'
Autor:
Robin Willenbring, Isaraphorn Pratumchai, Kristi Marquardt, Kerri A. Mowen, John R. Teijaro, Linda A. Sherman
Publikováno v:
The Journal of Immunology. 200:183.1-183.1
The PTPN22 alternative allele, PTPN22 1858T, is present in 5–10% of the North American population and is considered the highest autoimmune, non-HLA, risk allele. Extensive work has been done to better understand this allele in the context of autoim
Autor:
Robin Willenbring, Megan L Settell, Courtney Sarah Malo, Emma N Goddery, Michael J Hansen, Kevin D Pavelko, Larry R Pease, Aaron J Johnson
Publikováno v:
The Journal of Immunology. 198:78.10-78.10
The generation of an effective antiviral CD8 T cell response is required to protect C57BL/6 mice from Theiler’s murine encephalomyelitis virus (TMEV) induced demyelinating syndrome. Our group previously defined the VP2 121-130 peptide presented in
Publikováno v:
The Journal of Immunology. 196:188.25-188.25
Neuroinflammation is a putative mechanism of pathogen associated blood brain barrier (BBB) disruption. However, mechanisms of immune mediated vascular permeability remain an active topic of research. Our lab has defined a role for CD8 T cells and per
Autor:
Robin Willenbring, Holly Johnson, Fang Jin, Whitney Manhart, Stephanie LaFrance, Istvan Pirko, Aaron Johnson
Publikováno v:
The Journal of Immunology. 194:149.7-149.7
Despite numerous neurological disorders characterized by central nervous system (CNS) vascular permeability, the immune factors leading to pathology associated with blood-brain barrier (BBB) disruption remains poorly understood. To address this, we d
Publikováno v:
The Journal of Immunology. 188:67.4-67.4
Mast cells are involved in a range of physiologies and pathologies including allergic disease, defense against pathogens, and neutralization of venoms. Recently, these cells have been shown to play significant roles in inflammatory pain. Acute inflam