Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Robin W. Carrell"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The angiotensin peptides that control blood pressure are released from the non-inhibitory plasma serpin, angiotensinogen, on cleavage of its extended N-terminal tail by the specific aspartyl-protease, renin. Angiotensinogen had previously been assume
Externí odkaz:
https://doaj.org/article/570e02e5ab6c45ba9c3a284a94f7cc56
Autor:
Lina Ma, Jiawei Wu, Ying Zheng, Zimei Shu, Zhenquan Wei, Yinbiao Sun, Robin W. Carrell, Aiwu Zhou
Publikováno v:
Biomolecules, Vol 10, Iss 6, p 828 (2020)
Kallistatin, also known as SERPINA4, has been implicated in the regulation of blood pressure and angiogenesis, due to its specific inhibition of tissue kallikrein 1 (KLK1) and/or by its heparin binding ability. The binding of heparin on kallistatin h
Externí odkaz:
https://doaj.org/article/af328761971248dfa36d6c1323fe9532
Autor:
Fiona Broughton Pipkin, Robin W. Carrell, David A. Barrett, Yahui Yan, Lina A. Dahabiyeh, David Tooth, Randy J. Read
Publikováno v:
Analytical and Bioanalytical Chemistry
Angiotensinogen (AGT) is a critical protein in the renin-angiotensin-aldosterone system and may have an important role in the pathogenesis of pre-eclampsia. The disulphide linkage between cysteines 18 and 138 has a key role in the redox switch of AGT
Autor:
Ying Zheng, Jiawei Wu, Yinbiao Sun, Lina Ma, Zimei Shu, Robin W. Carrell, Zhenquan Wei, Aiwu Zhou
Publikováno v:
Biomolecules
Biomolecules, Vol 10, Iss 828, p 828 (2020)
Volume 10
Issue 6
Biomolecules, Vol 10, Iss 828, p 828 (2020)
Volume 10
Issue 6
Kallistatin, also known as SERPINA4, has been implicated in the regulation of blood pressure and angiogenesis, due to its specific inhibition of tissue kallikrein 1 (KLK1) and/or by its heparin binding ability. The binding of heparin on kallistatin h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc721c67e24003e677e9b792f24ce13
https://www.repository.cam.ac.uk/handle/1810/305886
https://www.repository.cam.ac.uk/handle/1810/305886
Autor:
Robin W. Carrell
Publikováno v:
Journal of Clinical Epidemiology. 127:223-224
Publikováno v:
Henley, D, Lightman, S & Carrell, R 2016, ' Cortisol and CBG : Getting cortisol to the right place at the right time ', Pharmacology and Therapeutics, vol. 166, pp. 128-135 . https://doi.org/10.1016/j.pharmthera.2016.06.020
Cortisol is transported in the blood by corticosteroid-binding globulin (CBG), a non-inhibitory member of the serpin family of serine protease inhibitors. Recent structural advances reveal how CBG acts as a releasing-agent as well as a carrier of cor
Autor:
Robin W. Carrell, Fei Zhang, Xin Huang, Aiwu Zhou, Yugang Wang, Zhenquan Wei, Ying Zheng, Guo-Qiang Chen, Randy J. Read
Publikováno v:
The Journal of Biological Chemistry
The Z mutation (E342K) of α1-antitrypsin (α1-AT), carried by 4% of Northern Europeans, predisposes to early onset of emphysema due to decreased functional α1-AT in the lung and to liver cirrhosis due to accumulation of polymers in hepatocytes. How
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context: Recent studies of corticosteroid-binding globulin (CBG) indicate that it does not merely transport cortisol passively but also actively regulates its release in the circulation. We show how CBG binding affinity can vary to give changes in fr
Autor:
Ronald Trubuhovich, Garth J. S. Cooper, Kevin Hicks, Norman Barlev, Peter Nobbs, M. A. H. ('Tony') Baird, Josie Sandercock, Linda Bryder, Valerie Smith, Iain Chalmers, Derek A. Dow, Paul Patten, Helen Overton, Elizabeth Overton, Robin W. Carrell, Amanda Burls, Colin Mantell, Marc J. N. C. Keirse
Publikováno v:
American Journal of Public Health
A letter to the editor in response to the article "The rationalization of unethical research: revisionist accounts of the Tuskegee Syphilis Study and the New Zealand 'Unfortunate Experiment'" by C. Paul and B. Brookes which was published in the 2015
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bcd59e5c3eca88ac74eba70f8e001c
https://openaccess.city.ac.uk/id/eprint/17363/8/Baird_201515358-final.pdf
https://openaccess.city.ac.uk/id/eprint/17363/8/Baird_201515358-final.pdf